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Том 12 №3 2010 год - Нефрология и диализ

Катастрофический антифосфолипидный синдром у молодой больной системной красной волчанкой

Козловская Н.Л. Томилина Н.А. Столяревич Е.С. Бирюкова Л.С. Скрябина И.А. Кальянова Е.В. Варясин В.В. Жукова М.Е.

Аннотация: В статье приводятся сведения о КАФС, в том числе основные концепции патогенеза, клинические проявления, морфологические особенности, подходы к диагностике и лечению, подчеркиваются его отличия от классических вариантов АФС – первичного и вторичного при СКВ. Обзор иллюстрирован клиническим наблюдением больной КАФС, развившимся как основное проявление СКВ. На примере представленного случая разбираются некоторые аспекты дифференциальной диагностики КАФС с другими микроангиопатическими синдромами – ГУС/ТТП и ДВС.

Для цитирования: Козловская Н.Л., Томилина Н.А., Столяревич Е.С., Бирюкова Л.С., Скрябина И.А., Кальянова Е.В., Варясин В.В., Жукова М.Е. Катастрофический антифосфолипидный синдром у молодой больной системной красной волчанкой. Нефрология и диализ. 2010. 12(3):208-219. doi:

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Ключевые слова: катастрофический антифосфолипидный синдром (КАФС), системная красная волчанка (СКВ), тромботическая тромбоцитопеническая пурпура, тромботическая микроангиопатия, ДВС-синдром, полиорганная недостаточность, catastrophic antiphospholipid syndrome (CAPS), systemic lupus erythematosus (SLE), thrombotic thrombocytopenic purpura, trombotic microangiopathies, disseminated intravascular coagulation syndrome

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