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Том 5 №4 2003 год - Нефрология и диализ

Ангиотензин II - современное представление о патогенезе нефросклероза (Обзор литературы)


Паунова С.С.

Аннотация: В конце ХХ века исследования различных видов повреждения почечной ткани показали, что применение ингибиторов ангиотензин-превращающего фермента (иАПФ) или антагонистов ангиотензина I (ATI) оказывает влияние на прогрессирование болезней почек, уменьшая протеинурию, инфильтрацию ткани почек воспалительными клетками и соответственно замедляя развитие фиброза [1, 13, 27, 41].

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Ключевые слова: ангиотензин II, нефросклероз, ингибиторы АПФ, ATI-рецепторы, АТII-рецепторы

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