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Том 12 №1 2010 год - Нефрология и диализ

Хроническая болезнь почек у больных с хронической сердечной недостаточностью (Обзор литературы)


Резник Е.В. Гендлин Г.Е. Гущина В.М. Сторожаков Г.И.

Аннотация: У больных с хронической сердечной недостаточностью (ХСН) часто развивается хроническая болезнь почек (ХБП), что оказывает неблагоприятное прогностическое влияние. Основными звеньями патогенеза ХБП при ХСН являются снижение сердечного выброса, активация нейрогуморальных систем, воспаление и оксидативный стресс. Для замедления прогрессирования ХБП пациентам с ХСН необходимы строгий контроль АД и гликемии, назначение ингибиторов ангиотензин-превращающего фермента или антагонистов рецепторов ангиотензина II. Изучается нефропротективное и прогностическое значение блокаторов А1-рецепторов аденозина, антагонистов рецепторов V2 вазопрессина, блокаторов рецепторов к эндотелину, препаратов эритропоэтина.

Для цитирования: Резник Е.В., Гендлин Г.Е., Гущина В.М., Сторожаков Г.И. Хроническая болезнь почек у больных с хронической сердечной недостаточностью (Обзор литературы). Нефрология и диализ. 2010. 12(1):013-024. doi:

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Ключевые слова: кардиоренальный синдром, дисфункция почек, хроническая болезнь почек, микроальбуминурия, хроническая сердечная недостаточность, почечная недостаточность, прогноз, скорость клубочковой фильтрации, cardiorenal syndrome, renal dysfunction, chronic kidney disease, microalbuminuria, chronic heart failure, renal insufficiency, prognosis, glomerular filtration rate

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