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Том 15 №2 2013 год - Нефрология и диализ

Железо (III) гидроксид олигоизомальтозат: новый препарат для коррекции дефицита железа у больных ХБП (Обзор литературы)


Ермоленко В.М. Филатова Н.Н.

Аннотация: В обзоре рассматриваются дискуссионные вопросы коррекции анемии у больных ХБП с нарушением функции почек. Особое внимание уделено препаратам железа, в частности, новому препарату – железо (III) гидроксид олигоизомальтозат 1000, который уже зарегистрирован в России. Линейная структура и сравнительно небольшая молекулярная масса минимизируют влияние препарата на иммунную систему, а матриксное расположение молекул железа обеспечивает его медленное высвобождение и крайне незначительное присутствие в сыворотке свободного железа, способного вызывать токсические эффекты. Железо (III) гидроксид олигоизомальтозат в дозе ³1000 мг можно вводить внутривенно в течение 15 мин без предварительной инфузии тестовой дозы.

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Ключевые слова: chronic kidney disease, anemia, iron drugs, epoetin, iron (III) hydroxide olygoisomaltozat, chronic kidney disease, anemia, iron drugs, epoetin, iron (III) hydroxide olygoisomaltozat

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