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Том 11 №4 2009 год - Нефрология и диализ

Активаторы рецепторов витамина D и сосудистая кальцификация (Обзор литературы)


Земченков А.Ю. Герасимчук Р.П.

Аннотация: В обзоре изложено современное представление о механизмах развития и патогенезе сосудистой кальцификации при хронической болезни почек. Представлена роль витамина D в процессах, связанных с сосудистой кальцификацией. Приведены данные о различии влияния на сосудистую кальцификацию разных активаторов рецепторов витамина D. Рассмотрены другие факторы, оказывающие влияние на сосудистую кальцификацию, а также известные плейотропные эффекты активаторов рецепторов витамина D.

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Ключевые слова: сосудистая кальцификация, минеральные и костные нарушения, хроническая болезнь почек, активаторы рецепторов витамина D, vascular calcification, mineral and bone disorders, chronic kidney disease, VDRA

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