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Том 10 №2 2008 год - Нефрология и диализ

Факторы риска гипертрофии миокарда при хронической болезни почек (Обзор литературы)


Бадаева С.В.

Аннотация: Как и сердечно-сосудистая патология в целом, распространенность гипертрофии левого желудочка (ГЛЖ) при хронической болезни почек (ХБП) намного превышает таковую в общей популяции. Если в общей популяции ее частота составляет 20% [83], то при ХБП она возрастает до 25-50% [77]. Более подробный анализ имеющихся на сегодняшний день исследований показывает, что частота ГЛЖ зависит от стадии ХБП. По данным ряда авторов она выявляется у 20% больных при снижении СКФ до 60-50 мл/мин, несколько чаще (31-35%) - при снижении СКФ до 49-25 мл/мин, и значительно чаще (42-45%) при дальнейшем ухудшении функции почек, снижении СКФ до 25-16 мл/мин [77, 102]. К началу диализа ГЛЖ выявляется у 75-85% больных, что соответствует распространенности этой патологии в популяции больных, получающих лечение ПГД и ПАПД [7, 49]. У реципиентов почечного трансплантата ГЛЖ выявляется в 50-70% случаев [61, 65].

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Ключевые слова: гипертрофия миокарда, хроническая болезнь почек, факторы риска

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