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Том 10 №2 2008 год - Нефрология и диализ

Низкомолекулярный декстран железа и сахарат железа обладают сравнимыми параметрами безопасности при хронических заболеваниях почек


Ауэрбах М. Талиб К.Ал.

Аннотация: Тяжелые побочные реакции, встречавшиеся при применении декстрана железа, были обусловлены препаратами с высокой молекулярной массой. Суждения о том, что сахарат и глюконат железа более безопасны, чем декстран железа, преждевременны. Проанализированы опубликованные сравнения данных о безопасности доступных препаратов парентерального железа. Встречаются неоптимальные схемы применения препаратов железа у пациентов на додиализной стадии хронических заболеваний почек. Мы рекомендуем инфузию общей дозы низкомолекулярного декстрана железа как метод выбора для восполнения железа. Kidney International (2008) 73, 528-530.

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