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Том 5 №2 2003 год - Нефрология и диализ

Ренальный тубулярный ацидоз (Обзор литературы)

Вашурина Т.В. Сергеева Т.В.

Аннотация: Ренальный тубулярный ацидоз (РТА) - группа канальцевых заболеваний почек, которые характеризуются нарушением реабсорбции бикарбоната, секреции водородных ионов или сочетанием обоих дефектов и приводят к метаболическому ацидозу при сохранной клубочковой фильтрации.

Для цитирования: Вашурина Т.В., Сергеева Т.В. Ренальный тубулярный ацидоз (Обзор литературы). Нефрология и диализ. 2003. 5(2):122-127. doi:

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Ключевые слова: РТА I типа, РТА II типа, РТА III типа, РТА IV типа

Список литературы:

1. Alper S.L. Genetic diseases of acid-base transporters. Annu Rev Physiol 2002; 64: 899-923.
2. Alper S.L., Stuart-Tilley A.K., Biemesderfer E.D. et al. Immunolocalization of AE2 anion exchanger in rat kidney. Am J Physiol 1997; 273: F.601-F.614.
3. Arai K., Zachman K., Chrousos G.P. Polymorphisms of amiloride sensitive sodium channel subunits in five sporadic cases of pseudohypoaldosteronism: do they have pathological potential? J Clin Endocrinol Metab 1999; 84: 2434-2437.
4. Baird R.N., Orlowski J., Szabo E.Z. et al. Molecular cloning, genomic organization, and functional expression of Na+/H+ exchanger isoform 5 (NHE 5) from human brain. J Biol Chem 1999; 274: 4377-4382.
5. Battle D., Flores G. Underlying defects in distal renal tubular acidosis. New understandings. Am J Kidney Dis 1996; 27: 896-915.
6. Batlle D.C., Ghanekar H., Jain S. et al. Hereditary distal renal tubular acidosis: New understandings. Annu Rev Med 2001; 52: 471-484.
7. Brenes L.G., Brenes J.M., Hernandez M.M. Familial proximal renal tubular acidosis. A distinct disease entity. Am J Med 1977; 63: 244-252.
8. Cunningham J., Fraher L.J., Clemens T.L. et al. Chronic acidosis with metabolic bone disease. Am J Med 1982; 73: 199-204.
9. DuBose T.D. Hyperkalemic hyperchloremic metabolic acidosis: pathophysiologic insights. Kidney Int 1997; 51: 591-602.
10. Hanukoglu A. Type I pseudohypoaldosteronism includes two clinically and genetically distinct entities with either renal or multiple target organ defects. J Clin Endocrinol Metab 1991; 73: 936-944.
11. Iragashi T., Inatomi J., Sekine T. et al. Mutations in SLC4A4 cause permanent isolated proximal renal tubular acidosis with ocular abnormalities. Nature Genet 1999; 23: 264-266.
12. Iragashi T., Ishii T., Watanabe K. et al. Persistent isolated proximal renal tubular acidosis - a sistemic disease with a distinct clinical entity. Pediatr Nephrol 1994; 8: 70-71.
13. Gordon R.D., Geddes R.A., Pawsey G.K. et al. Hypertension and severe hyperkalemia associated with suppression of renin and aldosterone and completely reversed by dietary sodium restriction. Aust Ann Med 1970; 4: 287-294.
14. Kamel K.S., Briceno L.F., Sanchez M.D. et al. A new classification for renal defects in net acid excretion. Am J Kidney Dis 1997; 29: 136-146.
15. Karet F.E. Inherited renal tubular acidosis. Adv Nephrol 2000; 30: 147-161.
16. Karet F.E., Finberg K.E., Nelson R.D. et al. Mutations in the gene encoding B1 subunit of H+-ATPase cause renal tubular acidosis with sensoneural deafness. Nature Genet 1999; 21: 84-90.
17. Nagai R., Kooh S.W., Balfe J.W. et al. Renal tubular acidosis and osteopetrosis with carbonic anhydrase II deficiency: pathogenesis of impaired acidification. Pediatr Nephrol 1997; 11: 633-636.
18. Nash M.A., Torrado A.D., Greifer I. et al. Renal tubular acidosis in infants and children. J Pediatr 1972; 80: 738-748.
19. Norman M.E., Feldman N.I., Cohn R.M. et al. Urinary citrate excretion in the diagnosis of distal renal tubular acidosis. J Pediatr 1978; 92: 394-400.
20. Rodrigues-Soriano J. New insights into the pathogenesis of renal tubular acidosis - from functional to molecular studies. Pediatr Nephrol 2000; 14: 1121-1136.
21. Rodrigues-Soriano J. Renal Tubular Acidosis: The Clinical Entity. J Am Soc Nephrol 2002; 13: 2160-2170.
22. Rodrigues-Soriano J., Vallo A. Renal tubular acidosis. Pediatr Nephrol 1990; 4: 268-275.
23. Rodriguez-Soriano J., Vallo A., Castillo G. et al. Natural history of primary distal renal tubular acidosis treated since infancy. J Pediatr 1982; 101: 669-676.
24. Romero M.F., Boron W.F. Electrogenic Na+/HCO3- cotransporters: cloning and phisiology. Annu Rev Physiol 1999; 61: 699-723.
25. Rutherford P.A. Expression of Na+/H+ exchanger isoforms in the kidney - implications for renal function and disease. Nephrol Dial Transplant 1996; 11: 1711-1713.
26. Simpson D.P. Citrate excretion: a window on renal metabolism. Am J Physiol 1983; 244: F223-F234.
27. Soleimani M., Burnham C.E. Physiology and molecular aspects of the Na+/HCO3- cotransporters in health and disease processes. Kidney Int 2000; 57: 371-384.
28. Spitzer A., Edelmann C.M., Goldberg L. et al. Short stature, hyperkalemia, and acidosis: a defect in renal transport of potassium. Kidney Int 1973; 3: 251-257.
29. Tanner M.J. Band 3 anion exchanger and its involvement in erythrocyte and kidney disorders. Curr Opin Hematol 2002; 9: 133-139.
30. Tanner M.J. The structure and function of band 3 (AE1): recent developments. Mol Membr Biol 1997; 14: 155-165.
31. Yu H., Freedman B.I., Rich S.S. et al. Human Na+/H+ exchanger genes: identification of polimorphisms by radiation hybrid mapping and analysis of linkage in end stage renal disease. Hypertension 2000; 35: 135-143.