nidНефрология и диализNephrology and Dialysis1680-44222618-9801Российское диализное обществоnid-1041Research ArticleОБЗОРЫ И ЛЕКЦИИREVIEWS AND LECTURESАктиваторы рецепторов витамина D и сосудистая кальцификация (Обзор литературы)Vitamin D Receptor Activators and Vascular Calcification ReviewЗемченковА. Ю.ZemchenkovA. Yu.zemchenkov@nephro.ruГерасимчукР. П.GerasimchiukR. P.noemail@neicon.ruСанкт-Петербургская Государственная Медицинская Академия им. И.И. Мечникова; Городская Мариинская больница – Городской нефрологический центр, г. Санкт-ПетербургРоссияMechnikov St.-Petersburg State medical academy; Marrinsky city hospital, City Nephrology center, St.-PetersburgRussian FederationГородская Мариинская больница – Городской нефрологический центр, г. Санкт-ПетербургРоссияMarrinsky city hospital, City Nephrology center, St.-PetersburgRussian Federation200919062025114276291Copyright © Земченков А.Ю., Герасимчук Р.П., 20252025Земченков А.Ю., Герасимчук Р.П.Zemchenkov A.Y., Gerasimchiuk R.P.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://journal.nephro.ru/jour/article/view/1041

В обзоре изложено современное представление о механизмах развития и патогенезе сосудистой кальцификации при хронической болезни почек. Представлена роль витамина D в процессах, связанных с сосудистой кальцификацией. Приведены данные о различии влияния на сосудистую кальцификацию разных активаторов рецепторов витамина D. Рассмотрены другие факторы, оказывающие влияние на сосудистую кальцификацию, а также известные плейотропные эффекты активаторов рецепторов витамина D.

Up-to-date concept of mechanisms and pathogenesis of vascular calcification in chronic kidney disease are reviewed. Current view of the role of vitamin D in processes involved in development of vascular calcification is described. Different effects of vitamin D receptor activators (VDRA) on vascular calcification are presented. The other factors which affect the vascular calcification are described. pleiotropic effects of VDRAs are reviewed.

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The authors declare that there are no conflicts of interest present.