References

nid

Нефрология и диализ

Nephrology and Dialysis

1680-44222618-9801

Российское диализное общество

nid-1310

Research Article

ОРИГИНАЛЬНЫЕ СТАТЬИ

ORIGINAL ARTICLES

Взаимосвязь артериальной гипертензии и изменений гемодинамики у больных с хронической почечной недостаточностью, получающих лечение перитонеальным диализом

Correlation of arterial hypertension and hemodynamic changes in patients with ESRD, treated by peritoneal dialysis

Новикова

Н. А.

Novikova

N. A.

rgmugt2@mail.ru

Гендлин

Г. Е.

Gendlin

G. E.

noemail@neicon.ru

Эттингер

О. А.

Ettinger

O. A.

noemail@neicon.ru

Сторожаков

Г. И.

Storozhakov

G. I.

noemail@neicon.ru

Томилина

Н. А.

Tomilina

N. A.

noemail@neicon.ru

Андрусев

А. М.

Andrusev

A. M.

noemail@neicon.ru

ГОУ ВПО РГМУ Росздрава, кафедра госпитальной терапии № 2Russian FederationМосковский нефрологический центр, ГКБ № 52, г. МоскваRussian Federation

2008

19062025

1014451

2025

Новикова Н.А., Гендлин Г.Е., Эттингер О.А., Сторожаков Г.И., Томилина Н.А., Андрусев А.М.

Novikova N.A., Gendlin G.E., Ettinger O.A., Storozhakov G.I., Tomilina N.A., Andrusev A.M.

Данная работа распространяется под лицензией Creative Commons Attribution 4.0.

This work is licensed under a Creative Commons Attribution 4.0 License.

https://journal.nephro.ru/jour/article/view/1310

Целями настоящего исследования были определение взаимосвязи между артериальной гипертензией (АГ) и показателями внутрисердечной гемодинамики в условиях изменяющегося интраперитонеального давления при обмене диализирующего раствора и изучение влияния изменений гомеостаза и транспортных характеристик перитонеальной мембраны на степень артериальной гипертензии у больных с терминальной хронической почечной недостаточностью, получающих лечение перитонеальным диализом. Сорока пациентам (23 женщинам и 17 мужчинам) было выполнено суточное мониторирование артериального давления (АД), биохимическое исследование крови и диализата, эхокардиографическое исследование при заполненной и “сухой” брюшной полости, при обмене диализирующего раствора регистрировалось АД на каждой минуте процедуры. Артериальная гипертензия была диагностирована у 95% больных, их которых гипотензивные препараты на момент начала исследования принимали 50%. Была выявлена ассоциация между АГ и снижением функции левого желудочка, усугубляющейся у пациентов с более высокими цифрами АД при наполнении брюшной полости диализирующим раствором. Показано, что целевые значения Kt/V и уровень альбумина крови ³38 г/л являются предикторами достижения лучшего контроля АД.

Our study was aimed to estimate correlation between arterial hypertension (AH) and characteristic of hemodinamic parametres in patients with ESRD, treated by PD, changes of blood pressure and hemodinamics during the exchange of dialysis solution and study the influence of homeostatic and peritoneal status on the degree of AH. 40 patients (23 women and 17 men) underwent 24-hour-long monitoring of BP, serum and dialyzate samples, echocardiography parameters in condition of peritoneal cavity filled with dialysis solution, with full or empty peritoneal cavity and with every minute control of blood pressure. Arterial hypertension was finded in 95% of all patients (50% of them received hypotensive druges). It was revealed association between AH and left ventricular systolic dysfunction, which progressed during filling of peritoneal cavity with dialysis solution in some patients. Better control of AH was associated with normal Kt/V and serum albumin ³38 g/l.

постоянный амбулаторный перитонеальный диализартериальная гипертензияфракция выброса левого желудочкаинтраперитонеальное давление

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The authors declare that there are no conflicts of interest present.