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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">nid</journal-id><journal-title-group><journal-title xml:lang="ru">Нефрология и диализ</journal-title><trans-title-group xml:lang="en"><trans-title>Nephrology and Dialysis</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1680-4422</issn><issn pub-type="epub">2618-9801</issn><publisher><publisher-name>Российское диализное общество</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">nid-1320</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ И ЛЕКЦИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS AND LECTURES</subject></subj-group></article-categories><title-group><article-title>Аутосомно-доминантная поликистозная болезнь почек: новые патогенетические и терапевтические аспекты</article-title><trans-title-group xml:lang="en"><trans-title>Autosomal dominant polycystic kidney disease (ADPKD): new pathogenetic and therapeutic approach</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ермоленко</surname><given-names>В. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Ermolenko</surname><given-names>V. M.</given-names></name></name-alternatives><email xlink:type="simple">nephrology@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Батэрдэнэ</surname><given-names>С. .</given-names></name><name name-style="western" xml:lang="en"><surname>Baterdene</surname><given-names>S. .</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>Кафедра нефрологии и гемодиализа ГОУ ДПО РМАПО Росздрава, г. Москва</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2008</year></pub-date><pub-date pub-type="epub"><day>19</day><month>06</month><year>2025</year></pub-date><volume>10</volume><issue>2</issue><fpage>111</fpage><lpage>122</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Ермоленко В.М., Батэрдэнэ С..., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Ермоленко В.М., Батэрдэнэ С...</copyright-holder><copyright-holder xml:lang="en">Ermolenko V.M., Baterdene S...</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.nephro.ru/jour/article/view/1320">https://journal.nephro.ru/jour/article/view/1320</self-uri><abstract><p>Еще Гиппократу были известны 4 болезни почек, две из которых с современных позиций классифицируются как мочекаменная и связанная с уретеральной обструкцией, третью не удается идентифицировать, а четвертая, представляет, по-видимому, описание поликистозной болезни почек и рекомендации по ее лечению, включая хирургическое (вскрытие абсцессов], хотя исходы хирургических вмешательств в то время в большинстве случаев были неутешительными. Даже Galen, врачевавший раны у гладиаторов и обладавший определенными хирургическими приемами, в своих трактатах не упоминал о хирургическом лечении болезней почек. Не исключают, что живший в VI веке Aetius, описавший макрогематурию при поднятии тяжести, падении с высоты и т. д., имел в виду больных с кистозным заболеванием почек.</p></abstract><kwd-group xml:lang="ru"><kwd>аутосомно-доминантная поликистозная болезнь почек: новые патогенетические и терапевтические аспекты</kwd><kwd>первичная цилия</kwd><kwd>механизмы цистогенезиса</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Кутырина И.М. Поликистоз почек. “Нефрология” Руководство для врачей. Ред. И. Е. Тареева. М.: Медицина 2000: 437-444.</mixed-citation><mixed-citation xml:lang="en">Кутырина И.М. Поликистоз почек. “Нефрология” Руководство для врачей. Ред. И. Е. Тареева. 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