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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">nid</journal-id><journal-title-group><journal-title xml:lang="ru">Нефрология и диализ</journal-title><trans-title-group xml:lang="en"><trans-title>Nephrology and Dialysis</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1680-4422</issn><issn pub-type="epub">2618-9801</issn><publisher><publisher-name>Российское диализное общество</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">nid-1359</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ШКОЛА НЕФРОЛОГА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>EDUCATIONAL MATERIALS</subject></subj-group></article-categories><title-group><article-title>Роль циклоспорина в лечении волчаночного нефрита (Обзор литературы и два наблюдения)</article-title><trans-title-group xml:lang="en"><trans-title>Role of cyclosporin in treatment of lupus nephritis (Review and case report)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Захарова</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Zakharova</surname><given-names>E. V.</given-names></name></name-alternatives><email xlink:type="simple">zakharoval@mtu-net.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>Московская городская клиническая больница имени С.П. Боткина, г. Москва</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2007</year></pub-date><pub-date pub-type="epub"><day>23</day><month>06</month><year>2025</year></pub-date><volume>9</volume><issue>2</issue><fpage>192</fpage><lpage>197</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Захарова Е.В., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Захарова Е.В.</copyright-holder><copyright-holder xml:lang="en">Zakharova E.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.nephro.ru/jour/article/view/1359">https://journal.nephro.ru/jour/article/view/1359</self-uri><abstract><p>Поражение почек является одним из наиболее частых и серьезных проявлений системной красной волчанки (СКВ), преобладающим вариантом является волчаночный нефрит (ВН), который выявляется у 25-50% больных уже к моменту установки диагноза. В целом частота ВН достигает у взрослых пациентов 60-70%, а гистологические изменения обнаруживается у 90% больных</p></abstract><kwd-group xml:lang="ru"><kwd>волчаночный нефрит</kwd><kwd>иммуносупрессивная терапия</kwd><kwd>циклоспорин</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Захарова Е.В. Прогнозирование исходов системной красной волчанки и системных васкулитов с экстраренальными и почечными проявлениями. Дисс…к.м.н. М.: 2005: 94-109.</mixed-citation><mixed-citation xml:lang="en">Захарова Е.В. Прогнозирование исходов системной красной волчанки и системных васкулитов с экстраренальными и почечными проявлениями. Дисс…к.м.н. М.: 2005: 94-109.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Тареева И.Е., Швецов М.Ю., Краснова Т.Н. и др. 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