nidНефрология и диализNephrology and Dialysis1680-44222618-9801Российское диализное обществоnid-1523Research ArticleОБЗОРЫ И ЛЕКЦИИREVIEWS AND LECTURESРевматоидный артрит как ведущая причина развития вторичного аа-амилоидоза (обзор литературы)Rheumatoid arthritis in development of secondary aa-amyloidosis (review)СаркисоваИ. А.SarkisovaI. A.noemail@neicon.ruМосковская Медицинская Академия им. И.М. Сеченова, г. МоскваRussian Federation200623062025811526Copyright © Саркисова И.А., 20252025Саркисова И.А.Sarkisova I.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://journal.nephro.ru/jour/article/view/1523

Трудно назвать какое-либо другое заболевание, кроме амилоидоза, в представлениях о котором в последнее время произошли бы такие существенные изменения. Это связано в первую очередь с установленной гетерогенностью белкового состава амилоидных фибрилл, что позволило выделить разные типы амилоида и на этом основании внести уточнения в классификацию амилоидоза и определить дифференцированные подходы к лечению. Благодаря большому вкладу в изучение проблемы амилоидоза специалистов различных направлений - не только интернистов, но и морфологов, биохимиков, генетиков - оказалось возможным понять механизмы развития амилоидоза, расширить круг методов диагностики и мониторирования заболевания. Новые принципы терапии определили необходимость пересмотра критериев выявления отдельных типов амилоидоза, поскольку ранняя диагностика во многом определяет успех лечения.

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The authors declare that there are no conflicts of interest present.