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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">nid</journal-id><journal-title-group><journal-title xml:lang="ru">Нефрология и диализ</journal-title><trans-title-group xml:lang="en"><trans-title>Nephrology and Dialysis</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1680-4422</issn><issn pub-type="epub">2618-9801</issn><publisher><publisher-name>Российское диализное общество</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">nid-1971</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>НАБЛЮДЕНИЯ ИЗ ПРАКТИКИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CASE REPORTS</subject></subj-group></article-categories><title-group><article-title>Трудности дифференциальной диагностики и лечения случая системной красной волчанки с быстропрогрессирующим гломерулонефритом и полиорганной недостаточностью</article-title><trans-title-group xml:lang="en"><trans-title>A case of sle with rapidly progressive glomerulonephritis and multiple organ failure - differential diagnosis and treatment</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Захарова</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Zakharova</surname><given-names>E. V.</given-names></name></name-alternatives><email xlink:type="simple">zakharoval@mtu-net.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Муравьев</surname><given-names>О. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Muravjov</surname><given-names>O. B.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Яковлева</surname><given-names>И. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Jakovleva</surname><given-names>I. I.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ипатьева</surname><given-names>Е. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Ipatjeva</surname><given-names>E. I.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>Московская городская клиническая больница им. С.П. Боткина, Москва</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2004</year></pub-date><pub-date pub-type="epub"><day>27</day><month>06</month><year>2025</year></pub-date><volume>6</volume><issue>3</issue><fpage>266</fpage><lpage>269</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Захарова Е.В., Муравьев О.Б., Яковлева И.И., Ипатьева Е.И., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Захарова Е.В., Муравьев О.Б., Яковлева И.И., Ипатьева Е.И.</copyright-holder><copyright-holder xml:lang="en">Zakharova E.V., Muravjov O.B., Jakovleva I.I., Ipatjeva E.I.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.nephro.ru/jour/article/view/1971">https://journal.nephro.ru/jour/article/view/1971</self-uri><abstract><p>Клинические проявления поражения почек встречаются более чем у половины пациентов с системной красной волчанкой, причем у 30% этих больных наблюдается быстропрогрессирующая почечная недостаточность, в 1-2% случаев встречается ОПН [<xref ref-type="bibr" rid="cit3">3</xref>]. В некоторых случаях заболевание может иметь бурное течение с выраженной гипертензией, отеками, сердечной недостаточностью, энцефалопатией и необратимым нарушением функции почек [<xref ref-type="bibr" rid="cit2">2</xref>]. Выполнение биопсии почки желательно у всех пациентов с волчанкой и признаками поражения почек, поскольку данные биопсии определяют прогноз и влияют на характер проводимого лечения [4, 5].</p></abstract></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Akhtar M., Al Dalaan A., El Ramahi K.M. Pauci-immune necrotizing lupus nephritis: report of two cases. Am J of Kidney Dis 1994; 23: 320-325.</mixed-citation><mixed-citation xml:lang="en">Akhtar M., Al Dalaan A., El Ramahi K.M. Pauci-immune necrotizing lupus nephritis: report of two cases. 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