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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">nid</journal-id><journal-title-group><journal-title xml:lang="ru">Нефрология и диализ</journal-title><trans-title-group xml:lang="en"><trans-title>Nephrology and Dialysis</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1680-4422</issn><issn pub-type="epub">2618-9801</issn><publisher><publisher-name>Российское диализное общество</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">nid-1997</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ И ЛЕКЦИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS AND LECTURES</subject></subj-group></article-categories><title-group><article-title>Ангиотензин II - современное представление о патогенезе нефросклероза (Обзор литературы)</article-title><trans-title-group xml:lang="en"><trans-title>Angiotensin II - current opinion about contribution to renal scar formation</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Паунова</surname><given-names>С. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Paunova</surname><given-names>S. S.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>Российский государственный медицинский университет, г. Москва</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2003</year></pub-date><pub-date pub-type="epub"><day>27</day><month>06</month><year>2025</year></pub-date><volume>5</volume><issue>4</issue><fpage>353</fpage><lpage>356</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Паунова С.С., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Паунова С.С.</copyright-holder><copyright-holder xml:lang="en">Paunova S.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.nephro.ru/jour/article/view/1997">https://journal.nephro.ru/jour/article/view/1997</self-uri><abstract><p>В конце ХХ века исследования различных видов повреждения почечной ткани показали, что применение ингибиторов ангиотензин-превращающего фермента (иАПФ) или антагонистов ангиотензина I (ATI) оказывает влияние на прогрессирование болезней почек, уменьшая протеинурию, инфильтрацию ткани почек воспалительными клетками и соответственно замедляя развитие фиброза [1, 13, 27, 41].</p></abstract><kwd-group xml:lang="ru"><kwd>ангиотензин II</kwd><kwd>нефросклероз</kwd><kwd>ингибиторы АПФ</kwd><kwd>ATI-рецепторы</kwd><kwd>АТII-рецепторы</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Нефрология. 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