nidНефрология и диализNephrology and Dialysis1680-44222618-9801Российское диализное обществоnid-3097Research ArticleОБЗОРЫ И ЛЕКЦИИREVIEWS AND LECTURESПроблема сердечно-сосудистых заболеваний при хронической почечной недостаточностиCardiovascular morbidity in patients with chronic renal insufficiencyТомилинаН. А.TomilinaN. A.noemail@neicon.ruВолгинаГ. В.VolginaG. V.noemail@neicon.ruБикбовБ. Т.BikbovB. T.noemail@neicon.ruКимИ. Г.KimI. G.noemail@neicon.ruНИИ трансплантологии и искусственных органов Минздрава РФ, г. МоскваRussian Federation200327062025511524Copyright © Томилина Н.А., Волгина Г.В., Бикбов Б.Т., Ким И.Г., 20252025Томилина Н.А., Волгина Г.В., Бикбов Б.Т., Ким И.Г.Tomilina N.A., Volgina G.V., Bikbov B.T., Kim I.G.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://journal.nephro.ru/jour/article/view/3097

Проблема кардиоваскулярной патологии при хронической почечной недостаточности (ХПН) является одной из наиболее актуальных в современной нефрологии. Это определяется тем, что сердечно-сосудистые заболевания (ССЗ) при терминальной ХПН возникают в среднем в 20-35 раз чаще, чем в общей популяции, и показатели кардиоваскулярной летальности в группах, сопоставимых по полу и возрасту, многократно превышают таковые в общей популяции [18, 23, 24, 51, 77, 86, 88, 117]. Так, у больных в возрасте 25-34 лет они в 120 раз выше, чем в той же возрастной группе в общей популяции. Для возрастной группы 55-64 лет это соотношение составляет 1:15, а для больных старше 85 лет - 1:3 [135]. Только патология сердца составляет в общей структуре смертности диализных больных 47% [150]. По данным Московского регистра больных с ХПН, удельный вес кардиоваскулярной летальности достигал в 1995-2000 гг. 42,3% в группе леченных перитонеальным диализом и 45,5% в популяции гемодиализных больных (рис. 1). После трансплантации почки ССЗ сохраняют свое лидирующее значение в структуре летальности. По данным Ojo и соавт. [113], они составляют 36% среди причин смерти реципиентов с функционирующим трансплантатом. По нашим собственным данным, основанным на 7-летних наблюдениях 314 пациентов, оперированных в 1995-1996 гг., величина этого показателя достигает 41%

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The authors declare that there are no conflicts of interest present.