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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">nid</journal-id><journal-title-group><journal-title xml:lang="ru">Нефрология и диализ</journal-title><trans-title-group xml:lang="en"><trans-title>Nephrology and Dialysis</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1680-4422</issn><issn pub-type="epub">2618-9801</issn><publisher><publisher-name>Российское диализное общество</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">nid-3210</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group></article-categories><title-group><article-title>Проблема неподатливости лечению у пациентов на программном гемодиализе</article-title><trans-title-group xml:lang="en"><trans-title>The problem of non-compliance in chronic hemodialysis patients</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шило</surname><given-names>В. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Shilo</surname><given-names>V. Y.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Горин</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Gorin</surname><given-names>A. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Денисов</surname><given-names>А. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Denisov</surname><given-names>A. Y.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Головкина</surname><given-names>Т. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Golovkina</surname><given-names>T. M.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сторожаков</surname><given-names>Г. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Storojakov</surname><given-names>G. I.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>Центр диализа при ГКБ № 20, кафедра госпитальной терапии № 2 РГМУ, г. Москва</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2002</year></pub-date><pub-date pub-type="epub"><day>28</day><month>06</month><year>2025</year></pub-date><volume>4</volume><issue>1</issue><fpage>45</fpage><lpage>48</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Шило В.Ю., Горин А.А., Денисов А.Ю., Головкина Т.М., Сторожаков Г.И., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Шило В.Ю., Горин А.А., Денисов А.Ю., Головкина Т.М., Сторожаков Г.И.</copyright-holder><copyright-holder xml:lang="en">Shilo V.Y., Gorin A.A., Denisov A.Y., Golovkina T.M., Storojakov G.I.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.nephro.ru/jour/article/view/3210">https://journal.nephro.ru/jour/article/view/3210</self-uri><abstract><p>С целью изучения проблемы неподатливости лечению обследовано 276 пациентов, находящихся на программном гемодиализе. Приведена характеристика причин неподатливости лечению в российской популяции гемодиализных пациентов. В результате сравнительного анализа податливых и неподатливых лечению пациентов по таким факторам, как возраст, пол, семейное положение, занятость, диагноз, наличие трансплантации в анамнезе, продолжительность диализа, показатели преддиализного артериального давления (АД), уровень гемоглобина, качество жизни, депрессия, тревога, астения, память, ценностные ориентации, индивидуально-типологические особенности, материальное положение, выявлены достоверные различия между этими группами по возрасту, качеству жизни (по SF-36), уровню преддиализного АД. Выявлено, что выживаемость неподатливых лечению пациентов значительно ниже, чем пациентов, податливых лечению.</p></abstract><trans-abstract xml:lang="en"><p>The purpose of the study was to examine the problem of non-compliance in 276 hemodialysis patients. We analyzed the reasons of non-compliance in Russian dialysis population. We found significant difference between non-compliant and compliant patients in age, quality of life (relying on SF-36) and blood pressure. Mortality risk of non-compliant patients was significantly higher compared with compliant patients.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>неподатливость лечению</kwd><kwd>non-compliance</kwd><kwd>compliance</kwd><kwd>качество жизни</kwd><kwd>гемодиализ</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Leggat J.E. Jr., Orzol S.M., Hulbert, Shearon T.E. et al. Non-compliance in hemodialysis: predictors and survival analysis. Am J Kidney Dis, 1998 Jul, 32: 1, 139-45.</mixed-citation><mixed-citation xml:lang="en">Leggat J.E. Jr., Orzol S.M., Hulbert, Shearon T.E. et al. Non-compliance in hemodialysis: predictors and survival analysis. 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