nidНефрология и диализNephrology and Dialysis1680-44222618-9801Российское диализное обществоnid-3262Research ArticleОБЗОРЫ И ЛЕКЦИИREVIEWS AND LECTURESГемодиафильтрация в лечении терминальной стадии почечной недостаточности (Обзор литературы)Hemodiafiltration in the treatment of ESRDРыбаковаО. Б.RybakovaO. B.noemail@neicon.ruДенисовА. Ю.DenisovA. Y.noemail@neicon.ruШилоВ. Ю.ShiloV. Y.noemail@neicon.ruОтделение гемодиализа ЦКБ МЦ УД Президента РФ; ООО «Международные диализные центры», МоскваRussian Federation20012806202534406410Copyright © Рыбакова О.Б., Денисов А.Ю., Шило В.Ю., 20252025Рыбакова О.Б., Денисов А.Ю., Шило В.Ю.Rybakova O.B., Denisov A.Y., Shilo V.Y.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://journal.nephro.ru/jour/article/view/3262

Обзор литературы, посвященной гемодиафильтрации. Рассматривается история вопроса, преимущества ГДФ, виды ГДФ. Обсуждаются основные черты частичного фильтрационного диализа, или диализа с частичной конвекционной добавкой, биофильтрации, безацетатной биофильтрации, ГДФ со стандартными замещающими растворами, High-flux ГДФ, гемодиафильтрация push-pull, ГДФ on-line. Хотя статистически не доказано, что ГДФ улучшает выживаемость больных, она, несомненно, увеличивает выведение средних молекул (β2-микроглобулин), позволяет лучше контролировать анемию при снижении дозы эритропоэтина и способствует большей гемодинамической стабильности пациентов в процессе проведения процедур.

The review of publication about the hemodiafiltration which includes the history of the hemodiafiltration, types of HDF and their advantages is presented. The general features of paired filtration dialysis (PFD), biofiltration, acetate free biofiltration, ready made substituat HDF, high-flux HDF, push-pull HDF, on-line HDF are discussed. Despite the absence of statistical proof of influence of HDF on patients survival rate, HDF increases «middle molecules» removal (β2-M), helps to control the anaemia with lower EPO doses and improves hemodynamic stability in the HDF session.

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The authors declare that there are no conflicts of interest present.