<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">nid</journal-id><journal-title-group><journal-title xml:lang="ru">Нефрология и диализ</journal-title><trans-title-group xml:lang="en"><trans-title>Nephrology and Dialysis</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1680-4422</issn><issn pub-type="epub">2618-9801</issn><publisher><publisher-name>Российское диализное общество</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">nid-3264</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group></article-categories><title-group><article-title>Нефропатия флебогипертензивного генеза и выбор метода лечения при варикоцеле у детей и подростков</article-title><trans-title-group xml:lang="en"><trans-title>Phleborenal hypertension nephropathy and choiсe of a method of treatment of varicocele in children and adolescents</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Страхов</surname><given-names>С. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Strakhov</surname><given-names>S. N.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бурков</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Burkov</surname><given-names>I. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Спиридонов</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Spiridonov</surname><given-names>A. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сапелкин</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Sapelkin</surname><given-names>S. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бондар</surname><given-names>З. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Bondar</surname><given-names>Z. M.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Косырева</surname><given-names>Н. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Kossyreva</surname><given-names>N. B.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Матар</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Matar</surname><given-names>A. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Басилая</surname><given-names>Л. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Bassilaya</surname><given-names>L. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>Отделение урологии и нейроурологии Московского НИИ педиатрии и детской хирургии МЗ РФ; детская городская клиническая больница № 9 им. Г.Н. Сперанского</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2001</year></pub-date><pub-date pub-type="epub"><day>28</day><month>06</month><year>2025</year></pub-date><volume>3</volume><issue>4</issue><fpage>414</fpage><lpage>420</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Страхов С.Н., Бурков И.В., Спиридонов А.А., Сапелкин С.В., Бондар З.М., Косырева Н.Б., Матар А.А., Басилая Л.В., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Страхов С.Н., Бурков И.В., Спиридонов А.А., Сапелкин С.В., Бондар З.М., Косырева Н.Б., Матар А.А., Басилая Л.В.</copyright-holder><copyright-holder xml:lang="en">Strakhov S.N., Burkov I.V., Spiridonov A.A., Sapelkin S.V., Bondar Z.M., Kossyreva N.B., Matar A.A., Bassilaya L.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.nephro.ru/jour/article/view/3264">https://journal.nephro.ru/jour/article/view/3264</self-uri><abstract><p>Цель: диагностика патологических нарушений функции левой почки, изменений гемодинамики и архитектоники левой почечной вены у больных варикоцеле для выявления генеза нефропатии и определения показаний для операций межвенозных анастомозов и окклюзирующих хирургических коррекций. Методы: тензиометрия, флебография, радиоиммунология, спектрометрия, радиометрия, жидкостная хроматография (450 больных варикоцеле 8-17 лет). Гипертензия левой почечной вены: давление от 10/8 (среднее 9) до 30/28 (среднее 28) мм рт. ст. левой почечной вены (195 больных), активация перекисного окисления, гипоксемия и другие нарушения функции почки трактуются как флебореногипертензионная нефропатия. Операции тестикуло-илиакальные венозные анастомозы (двунаправленный и однонаправленный) и ренокавальный анастомоз. Рецидивов нет. Нормотензия левой почечной вены (255 больных), незначительная аортомезентериальная компрессия левой почечной вены или отсутствие компрессии. Операции: эндоваскулярная склеротерапия левой тестикулярной вены (35). Рецидивов нет. После операции Иваниссевича (220) рецидив заболевания был выявлен в катамнезе у 5 детей. Высокий уровень 17-бета-эстрадиола в крови от левого яичка свидетельствует об орхопатии.</p></abstract><trans-abstract xml:lang="en"><p>Analysis were carried 450 patients with varicocele aged 8 to 17 years. The function of left and right kidney were separately evaluated. In 302 patients aortomesenteric compression of the left renal vein was diagnozed, 15 patients had stenosis of the left renal vein, 6 patients had retroaortal compression and 127 - were is not compression of the left renal vein. Of 450 patients 195 hed left-sidad phleborenal hypertension: pressure varied from 10/8 (mean 9) to 30/28 (mean 29) mm Hg. Left and right testicular estradiol levels 45,47 and 25,88 pg/l. The levels of xantinoxydase, of 5-hydroxyeicozotetraenic acid, of oxygen radicals, alkaline phosphatase, pCO2 in the left kidney were higher then those in the right kidney. Left renal venous hypertension, hypoxy, metabolic disturbances and other changes are interpreted as phleborenal nephropaty. Evidence is provided for indications for two-directional proxymal-distal (by A.A. Spiridonov’s procedure) testiculoiliacal (185) and renocaval (10) anastomosis, respectively. There was recidives no. Sclerotherapy - 35; o. Ivanissevich - 220.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>варикоцеле</kwd><kwd>нефропатия</kwd><kwd>флебогипертензия почек</kwd><kwd>стеноз и сдавление левой почечной вены</kwd><kwd>операции окклюзирующие и межсосудистые анастомозы</kwd><kwd>дети и подростки</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Bassi R., Radice F., Bergami G., DeGrazia F., Papa B. Surgical treatment of varicocele. Our experience in the last 10 years. Minerva-Chir. 1996; 51: 533-536.</mixed-citation><mixed-citation xml:lang="en">Bassi R., Radice F., Bergami G., DeGrazia F., Papa B. Surgical treatment of varicocele. Our experience in the last 10 years. Minerva-Chir. 1996; 51: 533-536.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Palmer L.S., Cohen S., Reda E.F., Gill B., Franco I., Kogan S.J., Levitt S.B. Intraoperative spermatic venography reconsidered. J. Urol. 1995; 154: 225-227.</mixed-citation><mixed-citation xml:lang="en">Palmer L.S., Cohen S., Reda E.F., Gill B., Franco I., Kogan S.J., Levitt S.B. Intraoperative spermatic venography reconsidered. J. Urol. 1995; 154: 225-227.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Mazzoni G., Fiocca G., Minucci S., Pieri S., Paolicelli D., Morucci M., Bibbolinо C., De Medici L., Calisti A. Varicocele: a multidisciplinary approach in children and adolescents. J. Urol. 1999; 162: 1755-1758.</mixed-citation><mixed-citation xml:lang="en">Mazzoni G., Fiocca G., Minucci S., Pieri S., Paolicelli D., Morucci M., Bibbolinо C., De Medici L., Calisti A. Varicocele: a multidisciplinary approach in children and adolescents. J. Urol. 1999; 162: 1755-1758.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Ardela-Diaz E., Gutierrez-Duenas J.M., Martin-Pinto F., Dominguez-Vallejo F.G., Cano-Lopez C. The spermatic venography in the treatment of varicocele in children. Cir-Pediatr. 1996; 9: 108-112.</mixed-citation><mixed-citation xml:lang="en">Ardela-Diaz E., Gutierrez-Duenas J.M., Martin-Pinto F., Dominguez-Vallejo F.G., Cano-Lopez C. The spermatic venography in the treatment of varicocele in children. Cir-Pediatr. 1996; 9: 108-112.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Nyirady P., Pirot L., Altorjay A., Pelenyi A., Merksz M., Kiss A., Csontai A. Laparoscopic varicocele operation: a chance to prevent the recurrence. Acta Chir. Hung. 1998; 37: 201-204.</mixed-citation><mixed-citation xml:lang="en">Nyirady P., Pirot L., Altorjay A., Pelenyi A., Merksz M., Kiss A., Csontai A. Laparoscopic varicocele operation: a chance to prevent the recurrence. Acta Chir. Hung. 1998; 37: 201-204.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Fuse H., Okumura A., Sakamoto M., Ohta S., Katayama T. Laparoscopic varicocele ligation. Int. Urol. Nephrol. 1996; 28: 91-97.</mixed-citation><mixed-citation xml:lang="en">Fuse H., Okumura A., Sakamoto M., Ohta S., Katayama T. Laparoscopic varicocele ligation. Int. Urol. Nephrol. 1996; 28: 91-97.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Maione G. The application of microanastomoses in the surgical treatment of varicocele. Minerva Сhir. 1992; 47: 1323-1326.</mixed-citation><mixed-citation xml:lang="en">Maione G. The application of microanastomoses in the surgical treatment of varicocele. Minerva Сhir. 1992; 47: 1323-1326.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Lima M., Domini M., Libri M. The varicocele in pediatric age: 207 cases treated with microsurgical technique. Eur. J. Pediatr. Surg. 1997; 7: 30-33.</mixed-citation><mixed-citation xml:lang="en">Lima M., Domini M., Libri M. The varicocele in pediatric age: 207 cases treated with microsurgical technique. Eur. J. Pediatr. Surg. 1997; 7: 30-33.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Bomalaski M.D., Mills J.I., Argueso L.R., Fujitani R.M., Sago A.L., Josef A.E. Iliac vein compression syndrome: an unusual cause of varicocele. Vasc. Surg. 1993; 18: 1064-1068.</mixed-citation><mixed-citation xml:lang="en">Bomalaski M.D., Mills J.I., Argueso L.R., Fujitani R.M., Sago A.L., Josef A.E. Iliac vein compression syndrome: an unusual cause of varicocele. Vasc. Surg. 1993; 18: 1064-1068.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Спиридонов А.А., Страхов С.Н., Прядко С.И. Хирургическая коррекция регионарной почечной гипертензии (пластика левой почечной вены и тестикуло-илиакальные анастомозы). Ангиология и сосудистая хирургия. 1996; 3: 11-25.</mixed-citation><mixed-citation xml:lang="en">Спиридонов А.А., Страхов С.Н., Прядко С.И. Хирургическая коррекция регионарной почечной гипертензии (пластика левой почечной вены и тестикуло-илиакальные анастомозы). Ангиология и сосудистая хирургия. 1996; 3: 11-25.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Страхов С.Н. Варикозное расширение вен гроздевидного сплетения и семенного канатика (варикоцеле). М.: «Астра-семь», 2001: 3-235.</mixed-citation><mixed-citation xml:lang="en">Страхов С.Н. Варикозное расширение вен гроздевидного сплетения и семенного канатика (варикоцеле). М.: «Астра-семь», 2001: 3-235.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Дан В.Н., Кунцевич Г.И., Страхов С.Н., Коков Л.С., Сапелкин С.В. Роль дуплексного сканирования и рентгеноконтрастной флебографии в диагностике и определении тактики лечения больных с варикоцеле. Ультразвуковая диагностика. 2000; 3: 84-90.</mixed-citation><mixed-citation xml:lang="en">Дан В.Н., Кунцевич Г.И., Страхов С.Н., Коков Л.С., Сапелкин С.В. Роль дуплексного сканирования и рентгеноконтрастной флебографии в диагностике и определении тактики лечения больных с варикоцеле. Ультразвуковая диагностика. 2000; 3: 84-90.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Folkow B., Neil E. Circulation. 1971; Oxford University Press: 392-410.</mixed-citation><mixed-citation xml:lang="en">Folkow B., Neil E. Circulation. 1971; Oxford University Press: 392-410.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Страхов С.Н., Спиридонов А.А., Продеус П.П., Бондар З.М., Косырева Н.Б., Сельверова Н.Б., Прядко С.И. Изменения почечных и яичковых вен при левостороннем варикоцеле и выбор метода операции у детей и подростков. Урология и нефрология. 1998; 4: 13-18.</mixed-citation><mixed-citation xml:lang="en">Страхов С.Н., Спиридонов А.А., Продеус П.П., Бондар З.М., Косырева Н.Б., Сельверова Н.Б., Прядко С.И. Изменения почечных и яичковых вен при левостороннем варикоцеле и выбор метода операции у детей и подростков. Урология и нефрология. 1998; 4: 13-18.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Atikeler K., Yeni E., Semercioz A., Yalcin O., Baydinc C. The value of the gonadotrophin-releasing hormone test as a prognostic factor in infertile patients with varicocele. Br. J. Urol. 1996; 78: 632-634.</mixed-citation><mixed-citation xml:lang="en">Atikeler K., Yeni E., Semercioz A., Yalcin O., Baydinc C. The value of the gonadotrophin-releasing hormone test as a prognostic factor in infertile patients with varicocele. Br. J. Urol. 1996; 78: 632-634.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Gershbein A.B., Horowitz M., Glassberg K.I. The adolescent varicocele I: left testicular hypertrophy following varicocelectomy. J. Urol. 1999; 162: 1447-1449.</mixed-citation><mixed-citation xml:lang="en">Gershbein A.B., Horowitz M., Glassberg K.I. The adolescent varicocele I: left testicular hypertrophy following varicocelectomy. J. Urol. 1999; 162: 1447-1449.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
