nidНефрология и диализNephrology and Dialysis1680-44222618-9801Российское диализное обществоnid-3300Research ArticleШКОЛА НЕФРОЛОГАEDUCATIONAL MATERIALSИшемическая болезнь сердца после трансплантации почкиСтюартГ. .StewartG. .A.G.Jardine@clinmed.Gla.Ac.UkДжардинА. Г.JardineA. G.noemail@neicon.ruБригсДж. Д.BriggsJ. D.noemail@neicon.ruПочечный центр, отдел медицины и терапии, западная больница, г. Глазго, ВеликобританияRussian Federation20012806202533381389Copyright © Стюарт Г..., Джардин А.Г., Бригс Д.Д., 20252025Стюарт Г..., Джардин А.Г., Бригс Д.Д.Stewart G..., Jardine A.G., Briggs J.D.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://journal.nephro.ru/jour/article/view/3300

Вступление Ранние сердечно-сосудистые заболевания (ССЗ) в настоящее время являются ведущей причиной смерти больных с пересаженной почкой [1, 2] и, как следствие, одной из основных причин потерь почечных трансплантатов [3]. Из этого следует, что более эффективное лечение ССЗ должно улучшить как выживаемость реципиентов почечного трансплантата (ПТ), так и выживаемость трансплантатов. Однако проблема состоит в том, что существующие методы лечения ССЗ у «не почечных» больных не всегда подходят реципиентам ПТ. Как и в общей популяции, после трансплантации почки ССЗ имеют комплексную природу. Последняя обусловлена процессами ускоренного атеросклероза, ведущего к развитию коронарной болезни сердца, и патологией миокарда (особенно гипертрофией левого желудочка - ГЛЖ), которая, в свою очередь, может быть причиной хронической сердечной недостаточности и внезапной смерти от аритмии. Более того, ССЗ (коронарная болезнь сердца или кардиомиопатия), развиваясь уже на ранних стадиях прогрессирующего почечного заболевания, после трансплантации почки могут стать необратимыми. Вопрос о естественном течении ССЗ у реципиентов ПТ остается предметом изучения. ** Публикуется по согласованию с автором и с разрешения Oxford University Press ** Перевод И.Г. Ким

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The authors declare that there are no conflicts of interest present.