nidНефрология и диализNephrology and Dialysis1680-44222618-9801Российское диализное обществоnid-3727Research ArticleОРИГИНАЛЬНЫЕ СТАТЬИORIGINAL ARTICLESКальцификация клапанов сердца у больных с терминальной хронической почечной недостаточностьюCardiac valve calcification in patients with end stage renal diseaseВолгинаГ. В.VolginaG. V.noemail@neicon.ruПерепеченыхЮ. В.PerepechenyhJ. V.noemail@neicon.ruБикбовБ. Т.BikbovB. T.noemail@neicon.ruКафедра внутренних болезней № 3 МГМСУ (зав. - академик РАМН, проф. Е.И. Соколов)Russian Federation200128062025314652Copyright © Волгина Г.В., Перепеченых Ю.В., Бикбов Б.Т., 20252025Волгина Г.В., Перепеченых Ю.В., Бикбов Б.Т.Volgina G.V., Perepechenyh J.V., Bikbov B.T.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://journal.nephro.ru/jour/article/view/3727

Обследовано 132 пациента с терминальной хронической почечной недостаточностью. Установлено, что у диализных больных с высокой частотой возникает кальцификация клапанов сердца. Предикторами развития кальцификации клапанов являлись возраст больных и длительность преддиализной артериальной гипертензии. Кальцификация митрального клапана была связана с гиперфосфатемией, увеличением произведения концентраций Са*Р и продолжительность гемодиализа. В развитии кальцификации аортального клапана наибольшее значение имели возраст, продолжительность предшествующей артериальной гипертензии и сохраняющаяся систолическая артериальная гипертензия, но не абсолютный уровень АД. Кальцификация митрального клапана и обоих клапанов сердца наиболее часто сочетаются с нарушениями сердечного ритма, а кальцификация аортального клапана с кальцификацией периферических сосудов и ишемической болезнью сердца.

132 patients with end stage of renal disease were enrolled in the study. We reveal a high prevalence of cardiac valve calcification among this population. Predictive factors for cardiac valve calcification were age and duration of predialysis systemic hypertension. Mitral valve calcification was associated with hyperphosphatemia, high calcium*phosphate product and duration of haemodialysis treatment. Aortic valve calcification correlated with age, maintenance of systemic hypertension but did not correlated with the level of blood pressure. Calcification of aortic valve was combined with calcification of arteries and coronary artery disease, whereas presence of mitral valve and both valves calcification was frequently combined with rhythm disturbances.

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The authors declare that there are no conflicts of interest present.