<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">nid</journal-id><journal-title-group><journal-title xml:lang="ru">Нефрология и диализ</journal-title><trans-title-group xml:lang="en"><trans-title>Nephrology and Dialysis</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1680-4422</issn><issn pub-type="epub">2618-9801</issn><publisher><publisher-name>Российское диализное общество</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">nid-3742</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>НАБЛЮДЕНИЯ ИЗ ПРАКТИКИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CASE REPORTS</subject></subj-group></article-categories><title-group><article-title>Случай успешного лечения СКВ; дифференциальная диагностика системных проявлений</article-title><trans-title-group xml:lang="en"><trans-title>A case of System Lupus Erythematosus; differential diagnostics of system manifestations</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Михайлова</surname><given-names>Н. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Mikhailova</surname><given-names>N. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Захарова</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Zakharova</surname><given-names>E. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ермоленко</surname><given-names>В. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Ermolenko</surname><given-names>V. M.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>МГКБ им. С.П. Боткина, отделение нефрологии; РМАПО, кафедра нефрологии и гемодиализа</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2001</year></pub-date><pub-date pub-type="epub"><day>28</day><month>06</month><year>2025</year></pub-date><volume>3</volume><issue>1</issue><fpage>106</fpage><lpage>110</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Михайлова Н.А., Захарова Е.В., Ермоленко В.М., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Михайлова Н.А., Захарова Е.В., Ермоленко В.М.</copyright-holder><copyright-holder xml:lang="en">Mikhailova N.A., Zakharova E.V., Ermolenko V.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.nephro.ru/jour/article/view/3742">https://journal.nephro.ru/jour/article/view/3742</self-uri><abstract><p>Представлен случай заболевания СКВ в сочетании с хроническим гепатитом С и вторичным серорезистентным сифилисом, отражающий трудности дифференциальной диагностики системных проявлений этих заболеваний и выбора тактики лечения. Общая продолжительность лечения и наблюдения составила 1,5 года. На фоне проводимой массивной иммуносупрессивной терапии достигнута полная клинико-лабораторная ремиссия СКВ без признаков активизации вирусной и трепонемной инфекций.</p></abstract><kwd-group xml:lang="ru"><kwd>системная красная волчанка</kwd><kwd>хронический гепатит С</kwd><kwd>методы диагностики</kwd><kwd>лечение</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Дворжанский С.И. Клиническая оценка серорезистентности при сифилисе. Русский медицинский журнал. 1998; 6; 15: 977-980.</mixed-citation><mixed-citation xml:lang="en">Дворжанский С.И. Клиническая оценка серорезистентности при сифилисе. Русский медицинский журнал. 1998; 6; 15: 977-980.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Самцов А.В. Клинические проявления первичного и вторичного сифилиса. Русский медицинский журнал. 1998; 6; 15: 972-980.</mixed-citation><mixed-citation xml:lang="en">Самцов А.В. Клинические проявления первичного и вторичного сифилиса. Русский медицинский журнал. 1998; 6; 15: 972-980.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">al Awadhi A., al. Jarallah K., Hasan F. et al. Rheumatic manifestation and immunological abnormalities in patients with chronic hepatitis C. A study in The Middle East. Rev Rhum Engl Ed 1998; 65: 6; 372-377.</mixed-citation><mixed-citation xml:lang="en">al Awadhi A., al. Jarallah K., Hasan F. et al. Rheumatic manifestation and immunological abnormalities in patients with chronic hepatitis C. A study in The Middle East. Rev Rhum Engl Ed 1998; 65: 6; 372-377.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Balikocioglu A., Quaidoo E., Vuletin J.C., Trotman B.W. Hepatitis and glomerulonefritis in secondary syphilis. J Assoc Acad Minor Phys 1991; 2: 2; 72-75.</mixed-citation><mixed-citation xml:lang="en">Balikocioglu A., Quaidoo E., Vuletin J.C., Trotman B.W. Hepatitis and glomerulonefritis in secondary syphilis. J Assoc Acad Minor Phys 1991; 2: 2; 72-75.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Cacoub P., Renou C., Rosenthal E. et al. Extrahepatic manifestations associated with hepatitis C virus infection. A prospective multicenter study of 321 patients. The GERMIVIC. Group d’Etude et de Recherche en Medecine Interne et Maladies Infectieuses sur le Virus de l’Hepatite C. Medicine (Baltimore) 2000 Jan; 79: 1; 47-56.</mixed-citation><mixed-citation xml:lang="en">Cacoub P., Renou C., Rosenthal E. et al. Extrahepatic manifestations associated with hepatitis C virus infection. A prospective multicenter study of 321 patients. The GERMIVIC. Group d’Etude et de Recherche en Medecine Interne et Maladies Infectieuses sur le Virus de l’Hepatite C. Medicine (Baltimore) 2000 Jan; 79: 1; 47-56.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Cacoub P., Poynard T., Ghillani P. et al. Extrahepatic manifestations of chronic hepatitis C. MULTIVIRC Group. Multidepartment Virus C. Arthritis Rheum 1999; 42: 10; 2204-12.</mixed-citation><mixed-citation xml:lang="en">Cacoub P., Poynard T., Ghillani P. et al. Extrahepatic manifestations of chronic hepatitis C. MULTIVIRC Group. Multidepartment Virus C. Arthritis Rheum 1999; 42: 10; 2204-12.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Fayyazi A., Schott P., Hartmann H. et al. Clinical, biochemical, and histological changes in hepatitis C virus infection-associated cryoglobulinemia. Z Gastroenterol 1997; 35: 10; 921-928.</mixed-citation><mixed-citation xml:lang="en">Fayyazi A., Schott P., Hartmann H. et al. Clinical, biochemical, and histological changes in hepatitis C virus infection-associated cryoglobulinemia. Z Gastroenterol 1997; 35: 10; 921-928.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Hruby Z., Kuzniar J., Rabczinski J. et al. The variety of clinical and histopathologic presentations of glomerulonephritis associated with latent syphilis.</mixed-citation><mixed-citation xml:lang="en">Hruby Z., Kuzniar J., Rabczinski J. et al. The variety of clinical and histopathologic presentations of glomerulonephritis associated with latent syphilis.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Ramos Casals M., Trejo O., Garcha Carrasco M. et al. Mixed cryoglobulinemia: new concepts. Lupus 2000; 9: 2; 83-91.</mixed-citation><mixed-citation xml:lang="en">Ramos Casals M., Trejo O., Garcha Carrasco M. et al. Mixed cryoglobulinemia: new concepts. Lupus 2000; 9: 2; 83-91.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
