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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">nid</journal-id><journal-title-group><journal-title xml:lang="ru">Нефрология и диализ</journal-title><trans-title-group xml:lang="en"><trans-title>Nephrology and Dialysis</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1680-4422</issn><issn pub-type="epub">2618-9801</issn><publisher><publisher-name>Российское диализное общество</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">nid-3788</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>22.10.99, МОСКВА, II СЪЕЗД НЕФРОЛОГОВ РОССИИ, СИМПОЗИУМ «ПЕРИТОНЕАЛЬНЫЙ ДИАЛИЗ: СОВРЕМЕННОЕ СОСТОЯНИЕ ВОПРОСА»</subject></subj-group></article-categories><title-group><article-title>Перитонеальный диализ в лечении хронической почечной недостаточности: достоинства, эффективность, проблемы длительного применения</article-title><trans-title-group xml:lang="en"><trans-title>The Role Of Peritoneal Dialysis In Renal Replacement Therapy: Advantages, Effectiveness And The Problem Of Long-term Treatment</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Томилина</surname><given-names>Н. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Tomilina</surname><given-names>N. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>НИИ трансплантологии и искусственных органов МЗ РФ, Москва</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2000</year></pub-date><pub-date pub-type="epub"><day>28</day><month>06</month><year>2025</year></pub-date><volume>2</volume><issue>1-2</issue><fpage>76</fpage><lpage>84</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Томилина Н.А., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Томилина Н.А.</copyright-holder><copyright-holder xml:lang="en">Tomilina N.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.nephro.ru/jour/article/view/3788">https://journal.nephro.ru/jour/article/view/3788</self-uri><abstract><p>Перитонеальный диализ (ПД) признается в настоящее время эффективным методом лечения хронической почечной недостаточности (ХПН). Технический прогресс двух последних десятилетий, как и значительное развитие представлений о биологии брюшины, способствовали широкому внедрению этого метода в повседневную клиническую практику. И с тех пор, как в 1976 г. впервые была предложена современная методика постоянного амбулаторного перитонеального диализа (ПАПД), количество больных, получающих это лечение, стремительно растет. Только за последние 17-18 лет оно увеличилось более чем в 30 раз: с 2 905 человек в 1981 г. до 115 000 в 1997 г. При этом особенно значимый прирост приходится на 90-е годы, в начале которых число ПД-пациентов увеличивалось ежегодно на 13-17%. И хотя далее этот темп несколько снизился, тем не менее, и в последние 5 лет количество ПД-больных ежегодно возрастает на 7,5% [<xref ref-type="bibr" rid="cit18">18</xref>].</p></abstract><kwd-group xml:lang="ru"><kwd>перитонеальный диализ</kwd><kwd>эффективность</kwd><kwd>хроническая почечная недостаточность</kwd><kwd>перитонеальный транспорт</kwd><kwd>ультрафильтрация</kwd><kwd>структура и функция перитонеальной мембраны</kwd><kwd>конечные продукты неферментативного гликозилирования</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Зверев Д.В. Роль перитонеального диализа в лечении почечной недостаточности у детей. Нефрология и диализ 1999; 1: 12-20.</mixed-citation><mixed-citation xml:lang="en">Зверев Д.В. Роль перитонеального диализа в лечении почечной недостаточности у детей. 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