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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">nid</journal-id><journal-title-group><journal-title xml:lang="ru">Нефрология и диализ</journal-title><trans-title-group xml:lang="en"><trans-title>Nephrology and Dialysis</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1680-4422</issn><issn pub-type="epub">2618-9801</issn><publisher><publisher-name>Российское диализное общество</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">nid-453</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group></article-categories><title-group><article-title>Динамика артериальной гипертензии и выживаемость у пациентов на гемодиализ</article-title><trans-title-group xml:lang="en"><trans-title>Arterial hypertension dynamics and survival in hemodialysis patients</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сабодаш</surname><given-names>А. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Sabodash</surname><given-names>A. B.</given-names></name></name-alternatives><email xlink:type="simple">sabodash@list.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Салихова</surname><given-names>К. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Salikhova</surname><given-names>K. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Земченков</surname><given-names>Г. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Zemchenkov</surname><given-names>G. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Макарова</surname><given-names>О. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Makarova</surname><given-names>O. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Скатерникова</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Skaternikova</surname><given-names>V. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Казанцева</surname><given-names>Н. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Banishevskaya</surname><given-names>A. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Банишевская</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kazantseva</surname><given-names>N. S.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Земченков</surname><given-names>А. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Zemchenkov</surname><given-names>A. Y.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Первый Санкт-Петербургский государственный медицинский университет им. И.П. Павлова; ББраун Авитум Руссланд Клиникс</institution><country>Россия</country></aff><aff xml:lang="en"><institution>I.P.Pavlov First Saint-Petersburg State medical university; B Braun Avitum Russland Clinics</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ББраун Авитум Руссланд Клиникс</institution><country>Россия</country></aff><aff xml:lang="en"><institution>B Braun Avitum Russland Clinics</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Первый Санкт-Петербургский государственный медицинский университет им. И.П. Павлова; Северо-Западный государственный медицинский университет им. И.И. Мечникова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>I.P.Pavlov First Saint-Petersburg State medical university; I.I.Mechnikov North-Western State medical university</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2016</year></pub-date><pub-date pub-type="epub"><day>19</day><month>08</month><year>2024</year></pub-date><volume>18</volume><issue>4</issue><fpage>416</fpage><lpage>430</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Сабодаш А.Б., Салихова К.А., Земченков Г.А., Макарова О.В., Скатерникова В.В., Казанцева Н.С., Банишевская А.В., Земченков А.Ю., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Сабодаш А.Б., Салихова К.А., Земченков Г.А., Макарова О.В., Скатерникова В.В., Казанцева Н.С., Банишевская А.В., Земченков А.Ю.</copyright-holder><copyright-holder xml:lang="en">Sabodash A.B., Salikhova K.A., Zemchenkov G.A., Makarova O.V., Skaternikova V.V., Banishevskaya A.V., Kazantseva N.S., Zemchenkov A.Y.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.nephro.ru/jour/article/view/453">https://journal.nephro.ru/jour/article/view/453</self-uri><abstract><p>Цель: оценить значение уровней артериального давления (АД), измеряемого в разных временных точках «диализной» недели, и его динамику на протяжении исследования для прогноза у гемодиализных пациентов. Пациенты и методы: у 133 пациентов одного диализного центра в трехлетнем проспективном исследовании оценено влияние уровней АД перед сеансом гемодиализа, в ходе, после сеанса, а также в междиализный интервал и динамики этих показателей на выживаемость пациентов. Результаты: АД у большинства пациентов, снижаясь в ходе диализа (на 7,4 мм Hg), продолжает уменьшаться в последующий междиализный день (на 2,2 мм Hg). АД перед сеансом составило 139±19 и 81±12, в целом, соответствуя целевому (&lt;140 и 90 мм Hg) у 59% женщин и 49% мужчин. Двухлетняя выживаемость с момента включения в исследование составила 87,7±3,0%, трехлетняя - 79,4±4,6%. Двухлетняя выживаемость пациентов по Kaplan-Meier не зависела от преддиализного и интрадиализного АД; влияние последиализного АД приближалось к статистической значимости при выделении подгруппы нижнего тертиля АД (р=0,08). Междиализное систолическое АД выше 123 мм Hg (граница нижнего и среднего тертиля) разделяло пациентов по выживаемости (р=0,04); статистически наиболее достоверным различие в выживаемости оказалось при разделении подгрупп по границе в 127 мм Hg (χ² в Log-Rank тесте = 4,77; р=0,029). В ходе исследования зафиксировано достоверное снижение всех параметров АД, но только динамика систолического междиализного АД была связана с лучшей выживаемостью (р=0,019). Заключение: АД в междиализные дни и его динамика в процессе коррекции в большей степени, чем АД на диализе и его динамика влияет на выживаемость пациентов.</p></abstract><trans-abstract xml:lang="en"><p>The aim: to evaluate arterial blood pressure (BP) measurement in different phases of “dialysis” week and its dynamics as a prognostic factor. Patients and method: 133 patients of a dialysis center were assessed in three years prospective study in conjunction with blood pressure measurement before, during, and after dialysis session and in the interdialytic interval as well as its changes during the study. Results: BP in most of patients decreases during dialysis session (by 6.9 mm Hg) and continues to decrease during interdialysis interval (by 2.2 mm Hg). BP before session was 139±19/81±12 mm Hg, being in target range (140/90 mm Hg) in 59% of women and 49% of men. Two year survival (Kaplan-Meier) was not associated with predialysis and intradialysis BP; the difference of survival was close to significance while comparing lower tertile of postdialysis BP with the rest of the group (p=0.08). Interdialysis BP higher than 123 mm Hg (the border between lower and medium tertile) divides patients by survival (p=0.04); this difference was the most significant while dividing by the border of 127 mm Hg (χ² in Log-Rank test = 4.77; р=0.029). During the study all parameters of BP decreased significantly, but only for interdialysis BP the positive dynamics was associated with better survival (p=0.019). Conclusion: The interdialysis BP and its dynamics during correction are significantly associated with survival while the peridialysis BP and its dynamics are not.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>гемодиализ</kwd><kwd>артериальная гипертензия</kwd><kwd>«домашнее» артериальное давление</kwd><kwd>междиализное артериальное давление</kwd><kwd>выживаемость</kwd><kwd>hemodialysis</kwd><kwd>arterial hypertension</kwd><kwd>«home» blood pressure</kwd><kwd>interdialysis blood pressure</kwd><kwd>survival</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Бикбов Б.Т. Томилина Н.А. Факторы риска смерти больных, впервые начинающих лечение гемодиализом (по данным Регистра Российского диализного общества). Нефрология и диализ. 2008. 10(1): 35-43</mixed-citation><mixed-citation xml:lang="en">Бикбов Б.Т. Томилина Н.А. 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Nephrol Dial Transplant. 2015. 30(9): 1443-8.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
