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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">nid</journal-id><journal-title-group><journal-title xml:lang="ru">Нефрология и диализ</journal-title><trans-title-group xml:lang="en"><trans-title>Nephrology and Dialysis</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1680-4422</issn><issn pub-type="epub">2618-9801</issn><publisher><publisher-name>Российское диализное общество</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.28996/2618-9801-2021-4-472-488</article-id><article-id custom-type="elpub" pub-id-type="custom">nid-46</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ И ЛЕКЦИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS AND LECTURES</subject></subj-group></article-categories><title-group><article-title>Проблемы оценки скорости клубочковой фильтрации у подростков и молодых взрослых: описательный обзор литературы и примеры из практики</article-title><trans-title-group xml:lang="en"><trans-title>Problems in the estimation of the glomerular filtration rate in adolescents and young adults: a narrative review and examples from clinical practice</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кулакова</surname><given-names>Е. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Kulakova</surname><given-names>E. N.</given-names></name></name-alternatives><email xlink:type="simple">elena.n.kulakova@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Настаушева</surname><given-names>Т. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Nastausheva</surname><given-names>T. L.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Звягина</surname><given-names>Т. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Zvyagina</surname><given-names>T. G.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Скрыльникова</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Skrylnikova</surname><given-names>M. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шлапакова</surname><given-names>Л. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Shlapakova</surname><given-names>L. N.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мокроусова</surname><given-names>А. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Mokrousova</surname><given-names>A. Yu.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хорошилова</surname><given-names>Ю. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Khoroshilova</surname><given-names>Yu. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО ВГМУ им. Н.Н. Бурденко Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>N.N. Burdenko Voronezh State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>БУЗ ВО Воронежская областная детская клиническая больница №1</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Voronezh Regional Children’s Clinical Hospital №1</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>21</day><month>06</month><year>2024</year></pub-date><volume>23</volume><issue>4</issue><fpage>472</fpage><lpage>488</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Кулакова Е.Н., Настаушева Т.Л., Звягина Т.Г., Скрыльникова М.А., Шлапакова Л.Н., Мокроусова А.Ю., Хорошилова Ю.В., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Кулакова Е.Н., Настаушева Т.Л., Звягина Т.Г., Скрыльникова М.А., Шлапакова Л.Н., Мокроусова А.Ю., Хорошилова Ю.В.</copyright-holder><copyright-holder xml:lang="en">Kulakova E.N., Nastausheva T.L., Zvyagina T.G., Skrylnikova M.A., Shlapakova L.N., Mokrousova A.Y., Khoroshilova Y.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.nephro.ru/jour/article/view/46">https://journal.nephro.ru/jour/article/view/46</self-uri><abstract><p>Формулы для расчета скорости клубочковой фильтрации (СКФ) в педиатрической практике отличаются от тех, которые используются для оценки функции почек у взрослых. В соответствии с «Клиническими практическими рекомендациями KDIGO 2012 по диагностике и лечению хронической болезни почек» для определения СКФ на основе креатинина сыворотки крови рекомендуется использовать формулы CKiD bedside (2009) у детей и CKD-EPI (2009) у взрослых. Эти формулы разрабатывались независимо друг от друга на основе параметров разных баз пациентов, что является причиной значительного несоответствия результатов расчета СКФ у пациентов 17-18 лет при переходе от одной формулы к другой. В последние годы ученые из США и Европы провели научные исследования по разработке и валидации новых формул для расчета СКФ. Необходимо обобщение этой опубликованной научной информации с целью определения путей оптимизации расчета СКФ у пациентов при переходе из педиатрической службы во взрослую службу системы здравоохранения. Для достижения поставленной цели выполнен описательный обзор, в котором обобщены данные всех доступных авторам научных публикаций о проблемах расчета СКФ у подростков и молодых взрослых. В историческом аспекте представлены предлагаемые пути решения этих проблем. Установлено, что на современном этапе отсутствует единый подход для расчета СКФ у этой возрастной группы, так как ни одна из используемых формул не обладает достаточной точностью. Новые формулы, разработанные в последние годы, такие как EKFC и CKiD U25, требуют дальнейших исследований для полноценной внешней валидации. До принятия консенсусных решений обеспечение преемственности расчета СКФ у подростков и молодых взрослых возможно за счет одновременного использования нескольких формул с обязательным указанием в медицинской документации их названий и метода определения креатинина.</p></abstract><trans-abstract xml:lang="en"><p>Formulas for estimation of the glomerular filtration rate (GFR) in pediatric practice differ from those used to assess kidney function in adults. The KDIGO 2012 Clinical Practice Guidelines for the Evaluation and Management of Chronic Kidney Disease recommends using the CKiD bedside (2009) equation for children and the CKD-EPI (2009) equation for adults to estimate GFR based on serum creatinine. These formulas were developed independently using different patient datasets. As such, there is a significant discrepancy in the estimated GFR in patients aged 17-18 years of age obtained using the different equations. In recent years, scientists from the United States and Europe have conducted several studies on the development and validation of new GFR-estimating formulas. An analysis of these published data is needed to identify the optimal GFR estimation approach for patients transitioning from pediatric to adult health care services. For this, a narrative review was carried out. The problems in estimating GFR in adolescents and young adults and the proposed ways of solving them are presented in a historical context. It was found that there is currently no unified approach for estimating GFR in this age group since none of the existing formulas is sufficiently accurate. New formulas developed in recent years, such as EKFC and CKiD U25, require further research for external validation. Before the adoption of consensus decisions, ensuring the continuity of GFR estimation in adolescents and young adults is possible by using several formulas simultaneously with the specification of the formula’s names and the creatinine determination method listed on the medical documentation.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>скорость клубочковой фильтрации</kwd><kwd>креатинин</kwd><kwd>хроническая болезнь почек</kwd><kwd>подростки</kwd><kwd>переход во взрослую службу здравоохранения</kwd></kwd-group><kwd-group xml:lang="en"><kwd>glomerular filtration rate</kwd><kwd>creatinine</kwd><kwd>chronic kidney disease</kwd><kwd>adolescents</kwd><kwd>transition from pediatric to adult health care services</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Kidney disease: Improving Global Outcomes (KDIGO) CKD Work Group. 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