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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">nid</journal-id><journal-title-group><journal-title xml:lang="ru">Нефрология и диализ</journal-title><trans-title-group xml:lang="en"><trans-title>Nephrology and Dialysis</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1680-4422</issn><issn pub-type="epub">2618-9801</issn><publisher><publisher-name>Российское диализное общество</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">nid-534</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group></article-categories><title-group><article-title>Прогностическое значение хронической болезни почек у больных, подвергнутых коррекции клапанных пороков сердца</article-title><trans-title-group xml:lang="en"><trans-title>Prognostic value of the chronic kidney disease in the patients undergoing correction of valve heart disease</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Искендеров</surname><given-names>Б. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Iskenderov</surname><given-names>B. G.</given-names></name></name-alternatives><email xlink:type="simple">iskenderovbg@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сисина</surname><given-names>О. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Sisina</surname><given-names>O. N.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Будаговская</surname><given-names>З. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Budagovskaya</surname><given-names>Z. M.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Пензенский институт усовершенствования врачей</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Penza Institute of Postgraduate Medical Training</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Пензенская городская клиническая больница скорой медицинской помощи, Пенза</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Penza city clinical Emergency Hospital, Penza</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2014</year></pub-date><pub-date pub-type="epub"><day>13</day><month>09</month><year>2024</year></pub-date><volume>16</volume><issue>1</issue><fpage>144</fpage><lpage>150</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Искендеров Б.Г., Сисина О.Н., Будаговская З.М., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Искендеров Б.Г., Сисина О.Н., Будаговская З.М.</copyright-holder><copyright-holder xml:lang="en">Iskenderov B.G., Sisina O.N., Budagovskaya Z.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.nephro.ru/jour/article/view/534">https://journal.nephro.ru/jour/article/view/534</self-uri><abstract><p>Цель исследования: определить ближайший и отдаленный послеоперационный прогноз у больных с хронической болезнью почек (ХБП), подвергнутых протезированию клапанных пороков сердца, в зависимости от развития острого повреждения почек (ОПП). Материал и методы. Обследовано 647 больных (298 мужчин и 349 женщин) в возрасте от 34 до 67 лет (52,7 ± 7,3 года), которым выполнялась коррекция клапанных пороков с использованием искусственного кровообращения. У 306 больных имело место снижение СКФ от 89 до 45 мл/мин/1,73 м2 (1-я группа), а у 341 больного СКФ была выше 90 мл/мин/1,73 м2 (2-я группа). ОПП диагностировали и классифицировали по уровню креатинина сыворотки крови, используя критерии RIFLE. Результаты. В 1-й группе ранние послеоперационные осложнения (инфаркт миокарда, инсульт, острая сердечная недостаточность, пароксизмальные тахиаритмии, сепсис, дыхательный дистресс) диагностировались достоверно чаще, чем во 2-й группе. В ранний период после операции ОПП возникло у 157 больных (51,3%) 1-й группы и у 103 больных (30,2%) 2-й группы (p &lt; 0,001). В 1-й группе гемодиализ проводился чаще (p = 0,003), и госпитальная летальность была выше (p &lt; 0,001), чем во 2-й группе. Через 12 месяцев после операции в 1-й группе у 68,5% больных достоверно увеличилась СКФ по сравнению с исходными значениями, в том числе у 46,5% больных, перенесших ОПП. Смертность амбулаторных больных в 1-й группе составила 5,4%, в том числе у 6,0% больных, перенесших ОПП, и у 4,3% больных без ОПП (p &gt; 0,05), а во 2-й группе - 2,7; 6,3 и 1,3% соответственно (p = 0,03). Заключение. Показано, что при наличии предшествующей ХБП у больных с корригированными клапанными пороками ближайший послеоперационный прогноз ухудшается, но отдаленный прогноз даже в случае развития ОПП, наоборот, улучшается у 46,5% больных.</p></abstract><trans-abstract xml:lang="en"><p>Aim: to determine short- and long-term postoperative prognosis in patients with chronic kidney disease (CKD) undergoing correction of valve heart disease depend on evolvement of acute kidney injury (AKI). Patients and methods. 647 patients (298 men and 349 women) aged from 34 till 67 years (average 52,7 ± 7,3 years) were examined whom the correction of valvular heart disease with cardiopulmonary bypass was performed. In 306 patients GFR decreased from 89 to 45 mL/min/1,73 m2 (1st group), but in 341 patients GFR was greater than 90 mL/min/1,73 m2 (2nd group). AKI was diagnosed and classified according to RIFLE-criteria by the change in serum creatinine (sCr). Results. The incidence of early postoperative complications (myocardial infarction, stroke, acute heart failure, paroxysmal tachiarrhythmias, sepsis, respiratory distress) was significantly higher in the 1st group than in the 2nd group. In the first days after operations AKI has developed in 157 patients (51,3%) in the 1st group and in 103 patients (30,2%) in the 2nd group (p &lt; 0,001). Renal replacement therapy (hemodialysis) was performed more frequently in the 1st group (p = 0,003), and in-hospital mortality was also higher in the 1st group (p &lt; 0,001) than in the 2nd group. Conclusion. It was shown that the presence of CKD in patients undergoing correction of valve heart disease and complicated with AKI has adverse influence on short-term postoperative prognosis and long-term prognosis is even better in 46,5% of them.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>протезирование клапанов сердца</kwd><kwd>острое повреждение почек</kwd><kwd>хроническая болезнь почек</kwd><kwd>heart valve replacement</kwd><kwd>acute kidney injury</kwd><kwd>chronic kidney disease</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Гарсиа-Донаире Ж.А., Руилопе Л.М. Кардио-васкулярно-ренальные связи в кардиоренальном континууме // Нефрология. 2013. Т. 17. № 1. 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