nidНефрология и диализNephrology and Dialysis1680-44222618-9801Российское диализное обществоnid-550Research ArticleОБЗОРЫ И ЛЕКЦИИREVIEWS AND LECTURESРоль почки в гормональных механизмах гомеостазаThe role of the kidney in hormonal mechanisms of homeostasisБагровЯ. Ю.BagrovY. Y.noemail@neicon.ruМанусоваН. Б.ManusovaN. B.manucova.nat@yandex.ruФГБУН «Институт эволюционной физиологии и биохимии им. И.М. Сеченова» РАНРоссияI.M. Sechenov Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Science, St. PetersburgRussian Federation201413092024163322327Copyright © Багров Я.Ю., Манусова Н.Б., 20242024Багров Я.Ю., Манусова Н.Б.Bagrov Y.Y., Manusova N.B.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://journal.nephro.ru/jour/article/view/550

Основная функция почки - поддержание водно-солевого гомеостаза. Гормональные механизмы работы почки позволяют ей участвовать в регуляции многих функций организма. Это достигается согласованностью работы транспортных систем почки и гормональных механизмов (эндокринных, паракринных, аутокринных). В кратком обзоре показано участие почки в некоторых физиологических и патологических процессах, требующих точной координации работы гормональных и транспортных систем, как почки, так и всего организма. Описано своеобразное участие почки через ангиотензин II в развитии плода при беременности. Гибкость и пластичность регуляции водно-солевого обмена при различных формах патологии позволяет относить эти функции почки к категории гомеостаза.

The main function of the kidneys is the maintenance of water-salt homeostasis. Hormonal mechanisms of kidney function allow it to participate in the regulation of many body functions. This is achieved by the consistent work of transport systems of the kidneys, and the hormonal (endocrine, paracrine, autocrine) mechanisms. In a brief overview we show the involvement of the kidneys in some physiological and pathological processes which require precise coordination of hormonal and transport systems of the kidneys and the whole body. The peculiarity of involvement of the kidney through angiotensin II in the development of the fetus during pregnancy is described. Flexibility and plasticity of regulation of water-salt metabolism in various forms of pathology can be attributed to these functions of the kidneys to the category of homeostasis.

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The authors declare that there are no conflicts of interest present.