nidНефрология и диализNephrology and Dialysis1680-44222618-9801Российское диализное обществоnid-576Research ArticleВСЕМИРНЫЙ ДЕНЬ ПОЧКИ 2013Острое почечное повреждение: предупреждение об опасностиAcute Kidney Injury: Global Health AlertФилипКам ТаоPhilipKam Taonoemail@neicon.ruЭммануэльА БардманнEmmanuelA Burdmannnoemail@neicon.ruРавиндраЛ. МетаRavindraL Mehtanoemail@neicon.ru201319092024151813Copyright © Филип К.Т., Эммануэль А.Б., Равиндра Л.М., 20242024Филип К.Т., Эммануэль А.Б., Равиндра Л.М.Philip K.T., Emmanuel A.B., Ravindra L.M.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://journal.nephro.ru/jour/article/view/576

Перевод с английского Е.В. Захаровой Для комитета по проведению Всемирного дня почки 2013* *Всемирный День Почки (ВДП) – совместная инициатива Международного Общества Нефрологов и Международной Федерации Почечных Фондов Члены комитета по проведению Всемирного Дня Почки: Мигуэль Риела (Бразилия, со-председатель), Джон Фили (Великобритания, со-председатель), Георги Абрахам (Индия), Пауль Биркенс (Нидерланды), Гильермо Гарсия-Гарсия (Мексика), Уильям Каузер (США), Филип К.Т. Ли (Гон Конг), Лука Сегантини (Бельгия), Пол Шэй (Канада), Тимур Эрк (Турция), Сара Мартин (Бельгия) Острое почечное повреждение (ОПП) становится все более распространенной патологией как в развивающихся, так и в развитых странах, и ассоциировано с значительной заболеваемостью и смертностью пациентов. В значительной мере развитие ОПП может быть предупреждено вмешательствами на различных уровнях медицинского обслуживания – индивидуальном, поликлиническом и госпитальном. Эффективные меры должны включать в первую очередь усилия, направленные на осведомленность общества о разрушительном влиянии ОПП на состояние здоровья населения, и выработку рекомендаций по предупреждению, раннему распознаванию и лечению ОПП. Усилия должны быть сконцентрированы на минимизации факторов, вызывающих ОПП, распространении информации о важности регулярного определения уровня сывороточного креатинина у пациентов из групп риска, и мониторирования объема мочи у пациентов, находящихся в критическом состоянии, с тем чтобы осуществлять возможно более раннюю диагностику; роль альтернативных биомаркеров ОПП до настоящего времени не определена. Необходимо создание протоколов для систематического лечения состояний, ведущих к развитию преренального ОПП, и специфических инфекций. Более точные данные о заболеваемости и клинической роли ОПП позволят повысить общественную значимость этой патологии, осведомленность правительственных и общественных организаций, представителей здравоохранения и практикующих врачей, что в конченом итоге позволит предотвращать развитие ОПП. Именно предотвращение является ключевым моментом, необходимым чтобы избежать тяжелых последствий – заболеваемости и смертности, ассоциированных с ОПП.

For the World Kidney Day Steering Committee 2013* *World Kidney Day (WKD) is a joint initiative of the International Society of Nephrology and the International Federations of Kidney Foundations WKD Steering Committee members: Miguel Riella (Brazil, co-chair), John Feehally (UK, co-chair), Timur Erk (Turkey), Paul Beerkens (Netherlands), Guillermo Garcia-Garcia (Mexico), Philip KT Li (Hong Kong), William G Couser (USA), Georgi Abraham (India), Paul Shay (Canada), Luca Segantini (Belgium), Sara Martin (Belgium) Acute kidney injury (AKI) is increasingly prevalent in developing and developed countries and is associated with severe morbidity and mortality. Most etiologies of AKI can be prevented by interventions at the individual, community, regional and in-hospital levels. Effective measures must include community-wide efforts to increase an awareness of the devastating effects of AKI and provide guidance on preventive strategies, as well as early recognition and management. Efforts should be focused on minimizing causes of AKI, increasing awareness of the importance of serial measurements of serum creatinine in high risk patients, and documenting urine volume in acutely ill people to achieve early diagnosis; there is as yet no definitive role for alternative biomarkers. Protocols need to be developed to systematically manage prerenal conditions and specific infections. More accurate data about the true incidence and clinical impact of AKI will help to raise the importance of the disease in the community, increase awareness of AKI by governments, the public, general and family physicians and other health care professionals to help prevent the disease. Prevention is the key to avoid the heavy burden of mortality and morbidity associated with AKI.

ReferencesKDIGO. Clinical Practice Guideline for Acute Kidney Injury // Kidney Int. 2012. Suppl 2. P. 1–138.KDIGO. Clinical Practice Guideline for Acute Kidney Injury // Kidney Int. 2012. Suppl 2. P. 1–138.Ali T., Khan I., Simpson W. et al. Incidence and outcomes in acute kidney injury: a comprehensive population-based study // J Am Soc Nephrol. 2007. Vol. 18. P. 1292–1298.Ali T., Khan I., Simpson W. et al. Incidence and outcomes in acute kidney injury: a comprehensive population-based study // J Am Soc Nephrol. 2007. Vol. 18. P. 1292–1298.Hsu C.Y., McCulloch C.E., Fan D. et al. Community-based incidence of acute renal failure // Kidney Int. 2007. Vol. 72. P. 208–212.Hsu C.Y., McCulloch C.E., Fan D. et al. Community-based incidence of acute renal failure // Kidney Int. 2007. Vol. 72. P. 208–212.Fang Y., Ding X., Zhong Y. et al. Acute kidney injury in a Chinese hospitalized population // Blood Purif. 2010. Vol. 30. P. 120–126.Fang Y., Ding X., Zhong Y. et al. Acute kidney injury in a Chinese hospitalized population // Blood Purif. 2010. Vol. 30. P. 120–126.Lafrance J.P., Miller D.R. Acute kidney injury associates with increased long-term mortality // J Am Soc Nephrol. 2010. Vol. 21. P. 345–352.Lafrance J.P., Miller D.R. Acute kidney injury associates with increased long-term mortality // J Am Soc Nephrol. 2010. Vol. 21. P. 345–352.Uchino S., Kellum J.A., Bellomo R. et al. Acute renal failure in critically ill patients: a multinational, multicenter study // JAMA. 2005. Vol. 294. P. 813–818.Uchino S., Kellum J.A., Bellomo R. et al. Acute renal failure in critically ill patients: a multinational, multicenter study // JAMA. 2005. Vol. 294. P. 813–818.Murugan R., Kellum J.A. Acute kidney injury: what's the prognosis? // Nat Rev Nephrol. 2011. Vol. 7. P. 209–217.Murugan R., Kellum J.A. Acute kidney injury: what's the prognosis? // Nat Rev Nephrol. 2011. Vol. 7. P. 209–217.Coca S.G., Singanamala S., Parikh C.R. Chronic kidney disease after acute kidney injury: a systematic review and meta-analysis // Kidney Int. 2012. Vol. 81. P. 442–448.Coca S.G., Singanamala S., Parikh C.R. Chronic kidney disease after acute kidney injury: a systematic review and meta-analysis // Kidney Int. 2012. Vol. 81. P. 442–448.Santos W.J., Zanetta D.M., Pires A.C. et al. Patients with ischaemic, mixed and nephrotoxic acute tubular necrosis in the intensive care unit – a homogeneous population? // Crit Care. 2006. Vol. 10. R68.Santos W.J., Zanetta D.M., Pires A.C. et al. Patients with ischaemic, mixed and nephrotoxic acute tubular necrosis in the intensive care unit – a homogeneous population? // Crit Care. 2006. Vol. 10. R68.Lombardi R., Yu L., Younes-Ibrahim M. et al. Epidemiology of acute kidney injury in Latin America // Semin Nephrol. 2008. Vol. 28. P. 320–329.Lombardi R., Yu L., Younes-Ibrahim M. et al. Epidemiology of acute kidney injury in Latin America // Semin Nephrol. 2008. Vol. 28. P. 320–329.Naicker S., Aboud O., Gharbi M.B. Epidemiology of acute kidney injury in Africa // Semin Nephrol. 2008. Vol. 28. P. 348–353.Naicker S., Aboud O., Gharbi M.B. Epidemiology of acute kidney injury in Africa // Semin Nephrol. 2008. Vol. 28. P. 348–353.Jha V., Rathi M. Natural medicines causing acute kidney injury // Semin Nephrol. 2008. Vol. 28 (4). P. 416–428.Jha V., Rathi M. Natural medicines causing acute kidney injury // Semin Nephrol. 2008. Vol. 28 (4). P. 416–428.Abdulkader R.C., Barbaro K.C., Barros E.J. et al. Nephrotoxicity of insect and spider venoms in Latin America // Semin Nephrol. 2008. Vol. 28. P. 373–382.Abdulkader R.C., Barbaro K.C., Barros E.J. et al. Nephrotoxicity of insect and spider venoms in Latin America // Semin Nephrol. 2008. Vol. 28. P. 373–382.Mehta R.L., Kellum J.A., Shah S.V. et al. Acute Kidney Injury Network: report of an initiative to improve outcomes in acute kidney injury // Crit Care. 2007. Vol. 11. R31.Mehta R.L., Kellum J.A., Shah S.V. et al. Acute Kidney Injury Network: report of an initiative to improve outcomes in acute kidney injury // Crit Care. 2007. Vol. 11. R31.Cruz D.N., Ricci Z., Ronco C. Clinical review: RIFLE and AKIN-time for reappraisal // Crit Care. 2009. Vol. 13. P. 211.Cruz D.N., Ricci Z., Ronco C. Clinical review: RIFLE and AKIN-time for reappraisal // Crit Care. 2009. Vol. 13. P. 211.Bellomo R., Kellum J.A., Ronco C. Acute kidney injury // Lancet. 2012. Vol. 380. P. 756–766.Bellomo R., Kellum J.A., Ronco C. Acute kidney injury // Lancet. 2012. Vol. 380. P. 756–766.Goldstein S.L. Acute kidney injury in children and its potential consequences in adulthood // Blood Purif. 2012. Vol. 33. P. 131–137.Goldstein S.L. Acute kidney injury in children and its potential consequences in adulthood // Blood Purif. 2012. Vol. 33. P. 131–137.Chronopoulos A., Cruz D.N., Ronco C. Hospital-acquired acute kidney injury in the elderly // Nat Rev Nephrol. 2010. Vol. 6. P. 141–149.Chronopoulos A., Cruz D.N., Ronco C. Hospital-acquired acute kidney injury in the elderly // Nat Rev Nephrol. 2010. Vol. 6. P. 141–149.Waikar S.S., Liu K.D., Chertow G.M. Diagnosis, epidemiology and outcomes of acute kidney injury // Clin J Am Soc Nephrol. 2008. Vol. 3. P. 844–861.Waikar S.S., Liu K.D., Chertow G.M. Diagnosis, epidemiology and outcomes of acute kidney injury // Clin J Am Soc Nephrol. 2008. Vol. 3. P. 844–861.Cerda J., Lameire N., Eggers P. et al. Epidemiology of acute kidney injury // Clin J Am Soc Nephrol. 2008. Vol. 3. P. 881–886.Cerda J., Lameire N., Eggers P. et al. Epidemiology of acute kidney injury // Clin J Am Soc Nephrol. 2008. Vol. 3. P. 881–886.Perazella M.A. Drug use and nephrotoxicity in the intensive care unit // Kidney Int 2012. Vol. 81. P. 1172–1178.Perazella M.A. Drug use and nephrotoxicity in the intensive care unit // Kidney Int 2012. Vol. 81. P. 1172–1178.Zarjou A., Agarwal A. Sepsis and acute kidney injury // J Am Soc Nephrol. 2011. Vol. 22. P. 999–1006.Zarjou A., Agarwal A. Sepsis and acute kidney injury // J Am Soc Nephrol. 2011. Vol. 22. P. 999–1006.Solomon R., Dauerman H.L. Contrast-induced acute kidney injury // Circulation. 2010. Vol. 122. P. 2451–2455.Solomon R., Dauerman H.L. Contrast-induced acute kidney injury // Circulation. 2010. Vol. 122. P. 2451–2455.Singbartl K., Kellum J.A. AKI in the ICU: definition, epidemiology, risk stratification, and outcomes // Kidney Int. 2012. Vol. 81. P. 819–825.Singbartl K., Kellum J.A. AKI in the ICU: definition, epidemiology, risk stratification, and outcomes // Kidney Int. 2012. Vol. 81. P. 819–825.NIH, NIDDKD, Bethesda, MD. USRDS 2010 Annual Data Report: Atlas of CKD and ESRD in the United States. 2010.NIH, NIDDKD, Bethesda, MD. USRDS 2010 Annual Data Report: Atlas of CKD and ESRD in the United States. 2010.Gonçalves G.M., Zamboni D.S., Câmara N.O. The role of innate immunity in septic acute kidney injuries // Shock. 2010. Vol. 34. Suppl 1. P. 22–26.Gonçalves G.M., Zamboni D.S., Câmara N.O. The role of innate immunity in septic acute kidney injuries // Shock. 2010. Vol. 34. Suppl 1. P. 22–26.Macedo E., Malhotra R., Bouchard J. et al. Oliguria is an early predictor of higher mortality in critically ill patients // Kidney Int. 2011. Vol. 80. P. 760–767.Macedo E., Malhotra R., Bouchard J. et al. Oliguria is an early predictor of higher mortality in critically ill patients // Kidney Int. 2011. Vol. 80. P. 760–767.MacLeod A. NCEPOD report on acute kidney injury – must do better // Lancet. 2009. Vol. 374. P. 1405–1406.MacLeod A. NCEPOD report on acute kidney injury – must do better // Lancet. 2009. Vol. 374. P. 1405–1406.Prescott A.M., Lewington A., O'Donoghue D. Acute kidney injury: top ten tips // Clin Med. 2012. Vol. 12. P. 328–332.Prescott A.M., Lewington A., O'Donoghue D. Acute kidney injury: top ten tips // Clin Med. 2012. Vol. 12. P. 328–332.Basu R.K., Chawla L.S., Wheeler D.S. et al. Renal angina: an emerging paradigm to identify children at risk for acute kidney injury // Pediatr Nephrol. 2012. Vol. 27. P. 1067–1078.Basu R.K., Chawla L.S., Wheeler D.S. et al. Renal angina: an emerging paradigm to identify children at risk for acute kidney injury // Pediatr Nephrol. 2012. Vol. 27. P. 1067–1078.Mammen C., Al Abbas A., Skippen P. et al. Long-term risk of CKD in children surviving episodes of acute kidney injury in the intensive care unit: a prospective cohort study // Am J Kidney Dis. 2012. Vol. 59. P. 523–530.Mammen C., Al Abbas A., Skippen P. et al. Long-term risk of CKD in children surviving episodes of acute kidney injury in the intensive care unit: a prospective cohort study // Am J Kidney Dis. 2012. Vol. 59. P. 523–530.Vieira J.M.Jr., Castro I., Curvello-Neto A. et al. Effect of acute kidney injury on weaning from mechanical ventilation in critically ill patients // Crit Care Med. 2007. Vol. 35. P. 184–191.Vieira J.M.Jr., Castro I., Curvello-Neto A. et al. Effect of acute kidney injury on weaning from mechanical ventilation in critically ill patients // Crit Care Med. 2007. Vol. 35. P. 184–191.Bouchard J., Soroko S.B., Chertow G.M. et al. Program to Improve Care in Acute Renal Disease (PICARD) Study Group. Fluid accumulation, survival and recovery of kidney function in critically ill patients with acute kidney injury // Kidney Int. 2009. Vol. 76. P. 422–427.Bouchard J., Soroko S.B., Chertow G.M. et al. Program to Improve Care in Acute Renal Disease (PICARD) Study Group. Fluid accumulation, survival and recovery of kidney function in critically ill patients with acute kidney injury // Kidney Int. 2009. Vol. 76. P. 422–427.Fischer M.J., Brimhall B.B., Parikh C.R. Uncomplicated acute renal failure and post-hospital care: a not so uncomplicated illness // Am J Nephrol. 2008. Vol. 28. P. 523–530.Fischer M.J., Brimhall B.B., Parikh C.R. Uncomplicated acute renal failure and post-hospital care: a not so uncomplicated illness // Am J Nephrol. 2008. Vol. 28. P. 523–530.Thakar C.V., Christianson A., Himmelfarb J. et al. Acute kidney injury episodes and chronic kidney disease risk in diabetes mellitus // Clin J Am Soc Nephrol. 2011. Vol. 6. P. 2567–2572.Thakar C.V., Christianson A., Himmelfarb J. et al. Acute kidney injury episodes and chronic kidney disease risk in diabetes mellitus // Clin J Am Soc Nephrol. 2011. Vol. 6. P. 2567–2572.Bydash J.R., Ishani A. Acute kidney injury and chronic kidney disease: a work in progress // Clin J Am Soc Nephrol. 2011. Vol. 6. P. 2555–2557.Bydash J.R., Ishani A. Acute kidney injury and chronic kidney disease: a work in progress // Clin J Am Soc Nephrol. 2011. Vol. 6. P. 2555–2557.Li P.K., Chow K.M., Matsuo S. et al. Asian Chronic Kidney Disease (CKD) Best Practice Recommendations – Positional Statements for Early Detection of CKD from Asian Forum for CKD Initiatives (AFCKDI) // Nephrology. 2011 (Carlton). Vol. 16. P. 633–641.Li P.K., Chow K.M., Matsuo S. et al. Asian Chronic Kidney Disease (CKD) Best Practice Recommendations – Positional Statements for Early Detection of CKD from Asian Forum for CKD Initiatives (AFCKDI) // Nephrology. 2011 (Carlton). Vol. 16. P. 633–641.Fliser D., Laville M., Covic A. et al. A European Renal Best Practice (ERBP) position statement on the Kidney Disease Improving Global Outcomes (KDIGO) Clinical Practice Guidelines on Acute Kidney Injury: Part 1: definitions, conservative management and contrast-induced nephropathy // Nephrol Dial Transplant. 2012 Oct. Vol. 19 [Epub ahead of print].Fliser D., Laville M., Covic A. et al. A European Renal Best Practice (ERBP) position statement on the Kidney Disease Improving Global Outcomes (KDIGO) Clinical Practice Guidelines on Acute Kidney Injury: Part 1: definitions, conservative management and contrast-induced nephropathy // Nephrol Dial Transplant. 2012 Oct. Vol. 19 [Epub ahead of print].Cho A., Lee J.E., Yoon J.Y. et al. Effect of an electronic alert on risk of contrast-induced acute kidney injury in hospitalized patients undergoing computed tomography // Am J Kidney Dis. 2012. Vol. 60. P. 74–81.Cho A., Lee J.E., Yoon J.Y. et al. Effect of an electronic alert on risk of contrast-induced acute kidney injury in hospitalized patients undergoing computed tomography // Am J Kidney Dis. 2012. Vol. 60. P. 74–81.Cox Z.L., Nelsen C.L., Waitman L.R. et al. Effects of clinical decision support on initial dosing and monitoring of tobramycin and amikacin // Am J Health Syst Pharm. 2011. Vol. 68. P. 624–632.Cox Z.L., Nelsen C.L., Waitman L.R. et al. Effects of clinical decision support on initial dosing and monitoring of tobramycin and amikacin // Am J Health Syst Pharm. 2011. Vol. 68. P. 624–632.Colpaert K., Hoste E.A., Steurbaut K. et al. Impact of real-time electronic alerting of acute kidney injury on therapeutic intervention and progression of RIFLE class // Crit Care Med. 2012. Vol. 40. P. 1164–1170.Colpaert K., Hoste E.A., Steurbaut K. et al. Impact of real-time electronic alerting of acute kidney injury on therapeutic intervention and progression of RIFLE class // Crit Care Med. 2012. Vol. 40. P. 1164–1170.Mehta R.L. Biomarker explorations in acute kidney injury: the journey continues // Kidney Int. 2011. Vol. 80. P. 332–334.Mehta R.L. Biomarker explorations in acute kidney injury: the journey continues // Kidney Int. 2011. Vol. 80. P. 332–334.Endre Z.H., Walker R.J., Pickering J.W. et al. Early intervention with erythropoietin does not affect the outcome of acute kidney injury (the EARLYARF trial) // Kidney Int. 2010. Vol. 77. P. 1020–1030.Endre Z.H., Walker R.J., Pickering J.W. et al. Early intervention with erythropoietin does not affect the outcome of acute kidney injury (the EARLYARF trial) // Kidney Int. 2010. Vol. 77. P. 1020–1030.Andrade L., de Francesco Daher E., Seguro A.C. Leptospiral nephropathy // Semin Nephrol. 2008. Vol. 28. P. 383–394.Andrade L., de Francesco Daher E., Seguro A.C. Leptospiral nephropathy // Semin Nephrol. 2008. Vol. 28. P. 383–394.Cerdá J., Bagga A., Kher V., Chakravarthi R.M. The contrasting characteristics of acute kidney injury in developed and developing countries // Nat Clin Pract Nephrol. 2008. Vol. 4. P. 138–153.Cerdá J., Bagga A., Kher V., Chakravarthi R.M. The contrasting characteristics of acute kidney injury in developed and developing countries // Nat Clin Pract Nephrol. 2008. Vol. 4. P. 138–153.Claure-Del Granado R., Macedo E., Chertow G.M. et al. Effluent volume in continuous renal replacement therapy overestimates the delivered dose of dialysis // Clin J Am Soc Nephrol. 2011. Vol. 6. P. 467–475.Claure-Del Granado R., Macedo E., Chertow G.M. et al. Effluent volume in continuous renal replacement therapy overestimates the delivered dose of dialysis // Clin J Am Soc Nephrol. 2011. Vol. 6. P. 467–475.Ponce D., Berbel M.N., Regina de Goes C. et al. High-volume peritoneal dialysis in acute kidney injury: indications and limitations // Clin J Am Soc Nephrol. 2012. Vol. 7. P. 887–894.Ponce D., Berbel M.N., Regina de Goes C. et al. High-volume peritoneal dialysis in acute kidney injury: indications and limitations // Clin J Am Soc Nephrol. 2012. Vol. 7. P. 887–894.Kilonzo K.G., Ghosh S., Temu S.A. et al. Outcome of acute peritoneal dialysis in northern Tanzania // Perit Dial Int. 2012. Vol. 32. P. 261–266.Kilonzo K.G., Ghosh S., Temu S.A. et al. Outcome of acute peritoneal dialysis in northern Tanzania // Perit Dial Int. 2012. Vol. 32. P. 261–266.

The authors declare that there are no conflicts of interest present.