nidНефрология и диализNephrology and Dialysis1680-44222618-9801Российское диализное обществоnid-579Research ArticleОБЗОРЫ И ЛЕКЦИИREVIEWS AND LECTURESОсобенности формирования кардиоренального синдрома при декомпенсации хронической сердечной недостаточности (Обзор литературы)Development of cardiorenal syndrome in decompensated heart failure (Review)ЩекочихинД. Ю.ShchekochikhinD. Y.agishm@list.ruКозловскаяН. Л.KozlovskayaN. L.noemail@neicon.ruКопыловФ. Ю.KopilovF. Y.noemail@neicon.ruПервый Московский Государственный Медицинский Университет им. И.М. СеченоваРоссияSechenov First Moscow State Medical UniversityRussian Federation2013190920241515964Copyright © Щекочихин Д.Ю., Козловская Н.Л., Копылов Ф.Ю., 20242024Щекочихин Д.Ю., Козловская Н.Л., Копылов Ф.Ю.Shchekochikhin D.Y., Kozlovskaya N.L., Kopilov F.Y.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://journal.nephro.ru/jour/article/view/579

Снижение фильтрационной функции почек у больных хронической сердечной недостаточностью (ХСН), как при ее стабильном течении, так и при декомпенсации, является распространенным фактором риска неблагоприятного исхода заболевания. В обзоре освещены эпидемиологические данные, а также патофизиологические механизмы кардио-ренальных взаимоотношений при стабильной и декомпенсированной ХСН. Рассмотрены многообразные причины снижения клубочковой фильтрации при декомпенсации ХСН, в том числе «псевдо-кардиоренальный синдром» в результате ятрогении. Обращено внимание практических врачей на сложности интерпретации ухудшения функции почек и выбора терапевтической тактики у больных тяжелой ХСН при быстром снижении СКФ.

Decreased renal function is a prevalent risk factor for unfavorable prognosis in patients with stable and decopmensated heart failure (HF). This review covers epidemiology data and pathophysiology of cardiorenal interactions in stable and decompensated HF. A variety of worsening renal function mechanisms in decompensated HF has been discussed, including «pseudo-cardiorenal syndrome» due to iatrogenesis. The complexities in understating the rapid decrease of GFR and clinical decision making in patients with advanced decompensated HF have been noted.

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The authors declare that there are no conflicts of interest present.