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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">nid</journal-id><journal-title-group><journal-title xml:lang="ru">Нефрология и диализ</journal-title><trans-title-group xml:lang="en"><trans-title>Nephrology and Dialysis</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1680-4422</issn><issn pub-type="epub">2618-9801</issn><publisher><publisher-name>Российское диализное общество</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">nid-824</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ПРАКТИЧЕСКИЕ РЕКОМЕНДАЦИИ</subject></subj-group></article-categories><title-group><article-title>Национальные рекомендации по МКН-ХБП: преемственность, современное состояние и перспективы (вместо предисловия)</article-title><trans-title-group xml:lang="en"><trans-title>National recommendations on ckd-mbd: succession, update and future (as a preface)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Земченков</surname><given-names>А. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Zemchenkov</surname><given-names>A. Yu.</given-names></name></name-alternatives><email xlink:type="simple">zau@mail.wplus.net</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Герасимчук</surname><given-names>Р. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Gerasimchuk</surname><given-names>R. P.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Санкт-Петербургская Государственная Медицинская Академия им. И.И. Мечникова, Городская Мариинская больница – Городской нефрологический центр</institution><country>Россия</country></aff><aff xml:lang="en"><institution>St.-Petersburg State Medical Academy named after I.I. Mechnikov St.-Petersburg State Healthcare Institution «City Mariinsky Hospital»</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2011</year></pub-date><pub-date pub-type="epub"><day>17</day><month>06</month><year>2025</year></pub-date><volume>13</volume><issue>1</issue><fpage>20</fpage><lpage>30</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Земченков А.Ю., Герасимчук Р.П., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Земченков А.Ю., Герасимчук Р.П.</copyright-holder><copyright-holder xml:lang="en">Zemchenkov A.Y., Gerasimchuk R.P.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.nephro.ru/jour/article/view/824">https://journal.nephro.ru/jour/article/view/824</self-uri><abstract><p>Вышедшие в свет в августе 2009 года рекомендации KDIGO по минеральным и костным нарушениям при хронической болезни почек построены на строгих принципах доказательной медицины, но и при отсутствии строгих доказательств могут использоваться как фундаментальная база для принятия решений у конкретных пациентов. Рассмотрение работ 2009–2010 годов, не вошедших в обоснования рекомендаций, или более ранних работ, не прошедших строгий отбор, а также наблюдательных исследований, поможет найти наиболее сбалансированные и целесообразные решения и избегнуть опасных крайностей в условиях, когда четкие рекомендации отсутствуют. Анализ представленных в настоящем обзоре работ, а также собственный клинический опыт позволили рабочей группе Российского Диализного Общества предложить адаптированный для российских условий вариант рекомендаций по МКН-ХБП. Мы надеемся на то, что их положения, регулярно обновляемые на специально созданном сайте www.ckd-mbd.ru, будут полезны практическим врачам.</p></abstract><trans-abstract xml:lang="en"><p>KDIGO Clinical Practice Guidelines for Chronic Kidney Disease-Mineral and Bone Disorder (CKD-MBD) issued in august 2009 were established on the strict principles of the evidence-based medicine, and even in conditions of lack of hard evidences may be used as a fundamental base for clinical decisions in definite patients. Taking in consideration studies not included in the recommendations rationale (issued after 2009 or failed to pass strict selection as well as observational studies) in the lack of strict algorithms may be also useful for making reasonable and balanced decisions. The analysis of the works included in this review and other studies as well as clinical experience allowed the work group of the Russian Dialysis Society to propose variant of ckd-mbd recommendations that is the adopted for Russian practice and dialysis population. We the hope that the guidelines, updated regularly on a specially designed web-site www.ckd-mbd.ru will be useful for practitioners.</p></trans-abstract></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Герасимчук Р.П., Земченков А.Ю., Кондаков С.Б., Медведева Е. Малоинвазивный метод коррекции вторичного гиперпаратиреоза при хронической болезни почек // Врач. 2009. № 11. С. 13–19.</mixed-citation><mixed-citation xml:lang="en">Герасимчук Р.П., Земченков А.Ю., Кондаков С.Б., Медведева Е. Малоинвазивный метод коррекции вторичного гиперпаратиреоза при хронической болезни почек // Врач. 2009. № 11. С. 13–19.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Ермоленко В.М., Родионова С.С., Павлова Е.А. и др. Спектр и лечение ренальной остеодистрофии у больных на постоянном амбулаторном перитонеальном диализе (собственные данные и обзор литературы) // Нефрология и диализ. 2004. Т. 6. № 2. С. 164–169.</mixed-citation><mixed-citation xml:lang="en">Ермоленко В.М., Родионова С.С., Павлова Е.А. и др. Спектр и лечение ренальной остеодистрофии у больных на постоянном амбулаторном перитонеальном диализе (собственные данные и обзор литературы) // Нефрология и диализ. 2004. Т. 6. № 2. С. 164–169.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Земченков А.Ю., Герасимчук Р.П. Сосудистая кальцификация и активаторы рецепторов витамина D. Обзор // Нефрология и диализ. 2009. Т. 11. № 4. С. 276–292.</mixed-citation><mixed-citation xml:lang="en">Земченков А.Ю., Герасимчук Р.П. Сосудистая кальцификация и активаторы рецепторов витамина D. Обзор // Нефрология и диализ. 2009. Т. 11. № 4. С. 276–292.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Земченков А.Ю., Конакова И.Н. Классификация хронической болезни почек: не настало ли время для ее пересмотра // Врач. 2009. № 7. С. 2–7.</mixed-citation><mixed-citation xml:lang="en">Земченков А.Ю., Конакова И.Н. Классификация хронической болезни почек: не настало ли время для ее пересмотра // Врач. 2009. № 7. С. 2–7.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Земченков А.Ю., Томилина Н.А. K/DOQI обращается к истокам хронической почечной недостаточности // Нефрология и диализ. 2004. Т. 6. № 3. С. 204–220.</mixed-citation><mixed-citation xml:lang="en">Земченков А.Ю., Томилина Н.А. K/DOQI обращается к истокам хронической почечной недостаточности // Нефрология и диализ. 2004. Т. 6. № 3. С. 204–220.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Клинические практические рекомендации K/DOQI (2003) по метаболизму кости и патологии скелета при хронических заболеваниях почек. Перевод с английского С.В. Лашутина // Нефрология и диализ. 2009. Приложение. С. 1–202.</mixed-citation><mixed-citation xml:lang="en">Клинические практические рекомендации K/DOQI (2003) по метаболизму кости и патологии скелета при хронических заболеваниях почек. Перевод с английского С.В. Лашутина // Нефрология и диализ. 2009. Приложение. С. 1–202.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Смирнов А.В., Есаян А.М., Каюков И.Г. Хроническая болезнь почек: на пути к единству представлений // Нефрология. 2002. Т. 6. № 4. С. 11–17.</mixed-citation><mixed-citation xml:lang="en">Смирнов А.В., Есаян А.М., Каюков И.Г. Хроническая болезнь почек: на пути к единству представлений // Нефрология. 2002. Т. 6. № 4. С. 11–17.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Arenas M.D., Rebollo P., Malek T. et al. A comparative study of 2 new phosphate binders (sevelamer and lanthanum carbonate) in routine clinical practice // J Nephrol. 2010. Vol. 23. № 6. P. 3683–3692.</mixed-citation><mixed-citation xml:lang="en">Arenas M.D., Rebollo P., Malek T. et al. A comparative study of 2 new phosphate binders (sevelamer and lanthanum carbonate) in routine clinical practice // J Nephrol. 2010. Vol. 23. № 6. P. 3683–3692.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Barreto D.V., Barreto F.C., Carvalho A.B. et al. Association of changes in bone remodeling and coronary calcification in hemodialysis patients: a prospective study // Am J Kidney Dis. 2008. Vol. 52. № 6. P. 1139–1350.</mixed-citation><mixed-citation xml:lang="en">Barreto D.V., Barreto F.C., Carvalho A.B. et al. Association of changes in bone remodeling and coronary calcification in hemodialysis patients: a prospective study // Am J Kidney Dis. 2008. Vol. 52. № 6. P. 1139–1350.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Blayney M.J., Tentori F. Trends and consequences of mineral bone disorder in haemodialysis patients: Lessons from the dialysis outcomes and practice patterns study (DOPPS) // Journal of Renal Care. 2009. Vol. 35. S1. P. 7–13.</mixed-citation><mixed-citation xml:lang="en">Blayney M.J., Tentori F. Trends and consequences of mineral bone disorder in haemodialysis patients: Lessons from the dialysis outcomes and practice patterns study (DOPPS) // Journal of Renal Care. 2009. Vol. 35. S1. P. 7–13.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Block G.A., Spiegel D.M., Ehrlich J. et al. Effects of sevelamer and calcium on coronary artery calcification in patients new to hemodialysis // Kidney Int. 2005. Vol. 68. № 4. P. 1815–1824.</mixed-citation><mixed-citation xml:lang="en">Block G.A., Spiegel D.M., Ehrlich J. et al. Effects of sevelamer and calcium on coronary artery calcification in patients new to hemodialysis // Kidney Int. 2005. Vol. 68. № 4. P. 1815–1824.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Block G.A., Zeig S., Sugihara J. et al. Combined therapy with cinacalcet and low doses of vitamin D sterols in patients with moderate to severe secondary hyperparathyroidism // Nephrol Dial Transplant. 2008. Vol. 23. № 7. P. 2311–2318.</mixed-citation><mixed-citation xml:lang="en">Block G.A., Zeig S., Sugihara J. et al. Combined therapy with cinacalcet and low doses of vitamin D sterols in patients with moderate to severe secondary hyperparathyroidism // Nephrol Dial Transplant. 2008. Vol. 23. № 7. P. 2311–2318.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Block G.A., Zaun D., Smits G. et al. Cinacalcet hydrochloride treatment significantly improves all-cause and cardiovascular survival in a large cohort of hemodialysis patients // Kidney Int. 2010. Vol. 78. № 6. P. 578–589.</mixed-citation><mixed-citation xml:lang="en">Block G.A., Zaun D., Smits G. et al. Cinacalcet hydrochloride treatment significantly improves all-cause and cardiovascular survival in a large cohort of hemodialysis patients // Kidney Int. 2010. Vol. 78. № 6. P. 578–589.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Campbell N., Pepper R.J., Yaqoob M.M. et al. The Use of Aluminium Containing Phosphate Binders in Haemodialysis Patients. ASN Renal week. 2009. Abstract PUB494.</mixed-citation><mixed-citation xml:lang="en">Campbell N., Pepper R.J., Yaqoob M.M. et al. The Use of Aluminium Containing Phosphate Binders in Haemodialysis Patients. ASN Renal week. 2009. Abstract PUB494.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Covic A., Fernandez-Martin J.L., Floege J. et al. Treatment of Secondary Hyperparathyroidism and K-DOQI Guidelines Achievement. COSMOS, a European Observational Study. Abstract F-PO1795 // J Am Soc Nephrol. 2008. Vol. 19. P. 507A.</mixed-citation><mixed-citation xml:lang="en">Covic A., Fernandez-Martin J.L., Floege J. et al. Treatment of Secondary Hyperparathyroidism and K-DOQI Guidelines Achievement. COSMOS, a European Observational Study. Abstract F-PO1795 // J Am Soc Nephrol. 2008. Vol. 19. P. 507A.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Eknoyan G. Chronic kidney disease definition and classification: no need for a rush to judgment // Kidney Int. 2009. Vol. 75. № 10. P. 1015.</mixed-citation><mixed-citation xml:lang="en">Eknoyan G. Chronic kidney disease definition and classification: no need for a rush to judgment // Kidney Int. 2009. Vol. 75. № 10. P. 1015.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Fishbane S., Shapiro W.B., Corry D.B. et al. Cinacalcet HCl and concurrent low-dose vitamin D improves treatment of secondary hyperparathyroidism in dialysis patients compared with vitamin D alone: the ACHIEVE study results // Clin J Am Soc Nephrol. 2008. Vol. 3. № 6. P. 1718–1725.</mixed-citation><mixed-citation xml:lang="en">Fishbane S., Shapiro W.B., Corry D.B. et al. Cinacalcet HCl and concurrent low-dose vitamin D improves treatment of secondary hyperparathyroidism in dialysis patients compared with vitamin D alone: the ACHIEVE study results // Clin J Am Soc Nephrol. 2008. Vol. 3. № 6. P. 1718–1725.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Floege J., Wheeler D., Ireland E. et al. Serum PTH and Mortality Risk in a Large Cohort of European Hemodialysis (HD) Patients: 2-Year ARO Results. Abstract F-PO1746 // J Am Soc Nephrol. 2008. Vol. 19. P. 502A.</mixed-citation><mixed-citation xml:lang="en">Floege J., Wheeler D., Ireland E. et al. Serum PTH and Mortality Risk in a Large Cohort of European Hemodialysis (HD) Patients: 2-Year ARO Results. Abstract F-PO1746 // J Am Soc Nephrol. 2008. Vol. 19. P. 502A.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Foley R.N., Parfrey P.S., Harrnett J.D. et al. Hypocalcemia, Morbidity, and Mortality in End-Stage Renal Disease // Am J Nephrol. 1996. Vol. 16. P. 386–393.</mixed-citation><mixed-citation xml:lang="en">Foley R.N., Parfrey P.S., Harrnett J.D. et al. Hypocalcemia, Morbidity, and Mortality in End-Stage Renal Disease // Am J Nephrol. 1996. Vol. 16. P. 386–393.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Foley R.N., Li S., Liu J. et al. The Fall and Rise of Parathyroidectomy in U.S. Hemodialysis Patients, 1992 to 2002 // J Am Soc Nephrol. Vol. 16. № 1. P. 210–218.</mixed-citation><mixed-citation xml:lang="en">Foley R.N., Li S., Liu J. et al. The Fall and Rise of Parathyroidectomy in U.S. Hemodialysis Patients, 1992 to 2002 // J Am Soc Nephrol. Vol. 16. № 1. P. 210–218.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">de Francisco A.L.M., Leidig M., Covic A.C. et al. Evaluation of calcium acetate/magnesium carbonate as a phosphate binder compared with sevelamer hydrochloride in haemodialysis patients: a controlled randomized study (CALMAG study) assessing efficacy and tolerability // Nephrol Dial Transplant. 2010. Vol. 25. P. 3707–3717.</mixed-citation><mixed-citation xml:lang="en">de Francisco A.L.M., Leidig M., Covic A.C. et al. Evaluation of calcium acetate/magnesium carbonate as a phosphate binder compared with sevelamer hydrochloride in haemodialysis patients: a controlled randomized study (CALMAG study) assessing efficacy and tolerability // Nephrol Dial Transplant. 2010. Vol. 25. P. 3707–3717.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Fukagawa M., Yumita S., Akizawa T. et al. Cinacalcet (KRN1493) effectively decreases the serum intact PTH level with favorable control of the serum phosphorus and calcium levels in Japanese dialysis patients // Nephrol Dial Transplant. 2008. Vol. 23. № 1. P. 328–335.</mixed-citation><mixed-citation xml:lang="en">Fukagawa M., Yumita S., Akizawa T. et al. Cinacalcet (KRN1493) effectively decreases the serum intact PTH level with favorable control of the serum phosphorus and calcium levels in Japanese dialysis patients // Nephrol Dial Transplant. 2008. Vol. 23. № 1. P. 328–335.</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Goldsmith D., Covic A., Fouque D. et al. Endorsement of the Kidney Disease Improving Global Outcomes (KDIGO) Chronic Kidney Disease–Mineral and Bone Disorder (CKD-MBD) Guidelines: a European Renal Best Practice (ERBP) commentary statement // NDT Advance Access published September 9, 2010, doi: 10.1093/ndt/gfq513</mixed-citation><mixed-citation xml:lang="en">Goldsmith D., Covic A., Fouque D. et al. Endorsement of the Kidney Disease Improving Global Outcomes (KDIGO) Chronic Kidney Disease–Mineral and Bone Disorder (CKD-MBD) Guidelines: a European Renal Best Practice (ERBP) commentary statement // NDT Advance Access published September 9, 2010, doi: 10.1093/ndt/gfq513</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Hirai T., Nakashima A., Takasugi N. et al. Response of secondary hyperparathyroidism to cinacalcet depends on parathyroid size // Nephron Clin Pract. 2010. Vol. 114. № 3. P. 187–193.</mixed-citation><mixed-citation xml:lang="en">Hirai T., Nakashima A., Takasugi N. et al. Response of secondary hyperparathyroidism to cinacalcet depends on parathyroid size // Nephron Clin Pract. 2010. Vol. 114. № 3. P. 187–193.</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">http://clinicaltrials.gov/ct2/results?term = NCT00977080: Evaluation of the Effectiveness of Paricalcitol Versus Cinacalcet With Low-Dose Vitamin D</mixed-citation><mixed-citation xml:lang="en">http://clinicaltrials.gov/ct2/results?term = NCT00977080: Evaluation of the Effectiveness of Paricalcitol Versus Cinacalcet With Low-Dose Vitamin D</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">http://clinicaltrials.gov/ct2/show/study/NCT00497146?term = PRIMO&amp;rank = 1</mixed-citation><mixed-citation xml:lang="en">http://clinicaltrials.gov/ct2/show/study/NCT00497146?term = PRIMO&amp;rank = 1</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">http://www.dopps.org/annualreport/html/pb_aub_c_TAB2009.htm</mixed-citation><mixed-citation xml:lang="en">http://www.dopps.org/annualreport/html/pb_aub_c_TAB2009.htm</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Huang C., Cheng K., Lin P. et al. Mortality Risk for Chinese Hemodialysis Patients with Disordered Bone Mineral Metabolism // ASN Renal week. 2009. Abstract F-PO1854.</mixed-citation><mixed-citation xml:lang="en">Huang C., Cheng K., Lin P. et al. Mortality Risk for Chinese Hemodialysis Patients with Disordered Bone Mineral Metabolism // ASN Renal week. 2009. Abstract F-PO1854.</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Ichii M., Ishimurab E., Okuno S. et al. Decreases in Parathyroid Gland Volume after Cinacalcet Treatment in Hemodialysis Patients with Secondary Hyperparathyroidism // Nephron Clin Pract. 2010. Vol. 115. P. 195–202.</mixed-citation><mixed-citation xml:lang="en">Ichii M., Ishimurab E., Okuno S. et al. Decreases in Parathyroid Gland Volume after Cinacalcet Treatment in Hemodialysis Patients with Secondary Hyperparathyroidism // Nephron Clin Pract. 2010. Vol. 115. P. 195–202.</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Jadoul M., Baños A., Zani V.J. et al. The effects of discontinuing cinacalcet at the time of kidney transplantation // NDT Plus. 2010. Vol. 3. № 1. P. 37–41.</mixed-citation><mixed-citation xml:lang="en">Jadoul M., Baños A., Zani V.J. et al. The effects of discontinuing cinacalcet at the time of kidney transplantation // NDT Plus. 2010. Vol. 3. № 1. P. 37–41.</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Kalantar-Zadeh K., Gutekunst L., Mehrotra R. et al. Understanding Sources of Dietary Phosphorus in the Treatment of Patients with Chronic Kidney Disease // Clin J Am Soc Nephrol. 2010. Vol. 5. P. 519–530.</mixed-citation><mixed-citation xml:lang="en">Kalantar-Zadeh K., Gutekunst L., Mehrotra R. et al. Understanding Sources of Dietary Phosphorus in the Treatment of Patients with Chronic Kidney Disease // Clin J Am Soc Nephrol. 2010. Vol. 5. P. 519–530.</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">KDIGO clinical practice guideline for the diagnosis, evaluation, prevention, and treatment of Chronic Kidney Disease-Mineral and Bone Disorder (CKD-MBD) // Kidney Int. Suppl. 2009. Vol. 113. P. 1–130.</mixed-citation><mixed-citation xml:lang="en">KDIGO clinical practice guideline for the diagnosis, evaluation, prevention, and treatment of Chronic Kidney Disease-Mineral and Bone Disorder (CKD-MBD) // Kidney Int. Suppl. 2009. Vol. 113. P. 1–130.</mixed-citation></citation-alternatives></ref><ref id="cit33"><label>33</label><citation-alternatives><mixed-citation xml:lang="ru">Kimata N., Akiba T., Pisoni R.L. et al. Mineral metabolism and haemoglobin concentration among haemodialysis patients in the Dialysis Outcomes and Practice Patterns Study (DOPPS) // Nephrol Dial Transplant. 2005. Vol. 20. P. 927–935.</mixed-citation><mixed-citation xml:lang="en">Kimata N., Akiba T., Pisoni R.L. et al. Mineral metabolism and haemoglobin concentration among haemodialysis patients in the Dialysis Outcomes and Practice Patterns Study (DOPPS) // Nephrol Dial Transplant. 2005. Vol. 20. P. 927–935.</mixed-citation></citation-alternatives></ref><ref id="cit34"><label>34</label><citation-alternatives><mixed-citation xml:lang="ru">Komaba H., Moriwaki K., Kamae I. et al. Towards cost-effective strategies for treatment of chronic kidney disease-mineral and bone disorder in Japan // Ther Apher Dial. 2009. Suppl. 1. P. 28–35.</mixed-citation><mixed-citation xml:lang="en">Komaba H., Moriwaki K., Kamae I. et al. Towards cost-effective strategies for treatment of chronic kidney disease-mineral and bone disorder in Japan // Ther Apher Dial. 2009. Suppl. 1. P. 28–35.</mixed-citation></citation-alternatives></ref><ref id="cit35"><label>35</label><citation-alternatives><mixed-citation xml:lang="ru">Kovesdy C.P., Kuchmak O., Lu J.L. et al. Outcomes Associated With Phosphorus Binders in Men With Non–Dialysis-Dependent CKD // Am J Kidney Dis. Vol. 56. № 5. P. 842–851.</mixed-citation><mixed-citation xml:lang="en">Kovesdy C.P., Kuchmak O., Lu J.L. et al. Outcomes Associated With Phosphorus Binders in Men With Non–Dialysis-Dependent CKD // Am J Kidney Dis. Vol. 56. № 5. P. 842–851.</mixed-citation></citation-alternatives></ref><ref id="cit36"><label>36</label><citation-alternatives><mixed-citation xml:lang="ru">Levey A., Atkins R., Coresh J. et al. Chronic kidney disease as a global public health problem: approaches and initiatives – a position statement from Kidney Disease: Improving Global Outcomes // Kidney Int. 2007. Vol. 72. P. 247–259.</mixed-citation><mixed-citation xml:lang="en">Levey A., Atkins R., Coresh J. et al. Chronic kidney disease as a global public health problem: approaches and initiatives – a position statement from Kidney Disease: Improving Global Outcomes // Kidney Int. 2007. Vol. 72. P. 247–259.</mixed-citation></citation-alternatives></ref><ref id="cit37"><label>37</label><citation-alternatives><mixed-citation xml:lang="ru">Levey A., Eckard K.-U., Tsukamoto Y. et al. Definition and classification of chronic kidney disease: A position statement from Kidney Disease: Improving Global Outcomes (KDIGO)// Kidney Int. 2005. Vol. 67. P. 2089–2100.</mixed-citation><mixed-citation xml:lang="en">Levey A., Eckard K.-U., Tsukamoto Y. et al. Definition and classification of chronic kidney disease: A position statement from Kidney Disease: Improving Global Outcomes (KDIGO)// Kidney Int. 2005. Vol. 67. P. 2089–2100.</mixed-citation></citation-alternatives></ref><ref id="cit38"><label>38</label><citation-alternatives><mixed-citation xml:lang="ru">Malluche H.H., Mawad H., Monier-Faugere M.C. The of bone health in end-stage renal disease: out of the frying pan, into the fire // Nephrol Dial Transplant. 2004. Vol. 19. Suppl. 1. P. 9–13.</mixed-citation><mixed-citation xml:lang="en">Malluche H.H., Mawad H., Monier-Faugere M.C. The of bone health in end-stage renal disease: out of the frying pan, into the fire // Nephrol Dial Transplant. 2004. Vol. 19. Suppl. 1. P. 9–13.</mixed-citation></citation-alternatives></ref><ref id="cit39"><label>39</label><citation-alternatives><mixed-citation xml:lang="ru">Manns B.J., Hodsman A., Zimmerman D.L. et al. Canadian Society of Nephrology Commentary on the 2009 KDIGO Clinical Practice Guideline for the Diagnosis, Evaluation, and Treatment of CKD–Mineral and Bone Disorder (CKD-MBD) // Am J Kidney Dis. 2010. Vol. 55. № 5. P. 800–812.</mixed-citation><mixed-citation xml:lang="en">Manns B.J., Hodsman A., Zimmerman D.L. et al. Canadian Society of Nephrology Commentary on the 2009 KDIGO Clinical Practice Guideline for the Diagnosis, Evaluation, and Treatment of CKD–Mineral and Bone Disorder (CKD-MBD) // Am J Kidney Dis. 2010. Vol. 55. № 5. P. 800–812.</mixed-citation></citation-alternatives></ref><ref id="cit40"><label>40</label><citation-alternatives><mixed-citation xml:lang="ru">Mazzaferro S., Perruzza I., Costantini S. et al. Relative roles of intestinal absorption and dialysis-fluid-related exposure in the accumulation of aluminium in haemodialysis patients // Nephrol. Dial Transplant. 1997. Vol. 12. № 12. P. 2679–2682.</mixed-citation><mixed-citation xml:lang="en">Mazzaferro S., Perruzza I., Costantini S. et al. Relative roles of intestinal absorption and dialysis-fluid-related exposure in the accumulation of aluminium in haemodialysis patients // Nephrol. Dial Transplant. 1997. Vol. 12. № 12. P. 2679–2682.</mixed-citation></citation-alternatives></ref><ref id="cit41"><label>41</label><citation-alternatives><mixed-citation xml:lang="ru">Miller J.E., Kovesdy C.P., Norris K.C. et al. Association of Cumulatively Low or High Serum Calcium Levels with Mortality in Long-Term Hemodialysis Patients // Am J Nephrol. 2010. Vol. 32. № 5. P. 403–413.</mixed-citation><mixed-citation xml:lang="en">Miller J.E., Kovesdy C.P., Norris K.C. et al. Association of Cumulatively Low or High Serum Calcium Levels with Mortality in Long-Term Hemodialysis Patients // Am J Nephrol. 2010. Vol. 32. № 5. P. 403–413.</mixed-citation></citation-alternatives></ref><ref id="cit42"><label>42</label><citation-alternatives><mixed-citation xml:lang="ru">Mittman N., Desiraju B., Meyer K.B. et al. Treatment of secondary hyperparathyroidism in ESRD: a 2-year, single-center crossover study // Kidney Int. 2010. Vol. 78. Suppl. 117. P. 33–36.</mixed-citation><mixed-citation xml:lang="en">Mittman N., Desiraju B., Meyer K.B. et al. Treatment of secondary hyperparathyroidism in ESRD: a 2-year, single-center crossover study // Kidney Int. 2010. Vol. 78. Suppl. 117. P. 33–36.</mixed-citation></citation-alternatives></ref><ref id="cit43"><label>43</label><citation-alternatives><mixed-citation xml:lang="ru">Moe S., Drüeke T, Cunningham J et al. Definition, evaluation, and classification of renal osteodystrophy: A position statement from Kidney Disease: Improving Global Outcomes (KDIGO) // Kidney Int. 2006. Vol. 69. № 11. P. 1945–1953.</mixed-citation><mixed-citation xml:lang="en">Moe S., Drüeke T, Cunningham J et al. Definition, evaluation, and classification of renal osteodystrophy: A position statement from Kidney Disease: Improving Global Outcomes (KDIGO) // Kidney Int. 2006. Vol. 69. № 11. P. 1945–1953.</mixed-citation></citation-alternatives></ref><ref id="cit44"><label>44</label><citation-alternatives><mixed-citation xml:lang="ru">Molina P., Sánchez-Pérez P., Peris A. Two Year Outcomes of a New Treatment Protocol for Controlling Bone Metabolism Parameters in Hemodialysis Patients // ASN Renal week. 2009. Abstract F-PO1854.</mixed-citation><mixed-citation xml:lang="en">Molina P., Sánchez-Pérez P., Peris A. Two Year Outcomes of a New Treatment Protocol for Controlling Bone Metabolism Parameters in Hemodialysis Patients // ASN Renal week. 2009. Abstract F-PO1854.</mixed-citation></citation-alternatives></ref><ref id="cit45"><label>45</label><citation-alternatives><mixed-citation xml:lang="ru">Monier-Faugere M.C., Malluche H.H. Trends in renalosteodystrophy: a survey from 1983 to 1995 in a total of 2248 patients // Nephrol Dial Transplant. 1996. Vol. 11. Suppl. 3. P. 111–120.</mixed-citation><mixed-citation xml:lang="en">Monier-Faugere M.C., Malluche H.H. Trends in renalosteodystrophy: a survey from 1983 to 1995 in a total of 2248 patients // Nephrol Dial Transplant. 1996. Vol. 11. Suppl. 3. P. 111–120.</mixed-citation></citation-alternatives></ref><ref id="cit46"><label>46</label><citation-alternatives><mixed-citation xml:lang="ru">National Kidney Foundation. K/DOQI clinical practice guidelines for bone metabolism and disease in chronic kidney disease // Am J Kidney Dis. 2003. Vol. 42. P. 1–201.</mixed-citation><mixed-citation xml:lang="en">National Kidney Foundation. K/DOQI clinical practice guidelines for bone metabolism and disease in chronic kidney disease // Am J Kidney Dis. 2003. Vol. 42. P. 1–201.</mixed-citation></citation-alternatives></ref><ref id="cit47"><label>47</label><citation-alternatives><mixed-citation xml:lang="ru">Navaneethan S.D., Palmer S.C., Craig J.C. et al. Benefits and harms of phosphate binders in CKD: a systematic review of randomized controlled trials // Am J Kidney Dis. 2009. Vol. 54. № 4. P. 619–637.</mixed-citation><mixed-citation xml:lang="en">Navaneethan S.D., Palmer S.C., Craig J.C. et al. Benefits and harms of phosphate binders in CKD: a systematic review of randomized controlled trials // Am J Kidney Dis. 2009. Vol. 54. № 4. P. 619–637.</mixed-citation></citation-alternatives></ref><ref id="cit48"><label>48</label><citation-alternatives><mixed-citation xml:lang="ru">Nguyen-Yamamoto L., Bolivar I., Strugnell S.A. et al. Comparison of Active Vitamin D Compounds and a Calcimimetic in Mineral Homeostasis // J Am Soc Nephrol. 2010. Vol. 21. P. 1713–1723.</mixed-citation><mixed-citation xml:lang="en">Nguyen-Yamamoto L., Bolivar I., Strugnell S.A. et al. Comparison of Active Vitamin D Compounds and a Calcimimetic in Mineral Homeostasis // J Am Soc Nephrol. 2010. Vol. 21. P. 1713–1723.</mixed-citation></citation-alternatives></ref><ref id="cit49"><label>49</label><citation-alternatives><mixed-citation xml:lang="ru">NKF: KDOQI Clinical Practice Guidelines for Chronic Kidney Disease: Evaluation, Classification and Stratification // Am J Kidney Dis. 2002. Vol. 39. Suppl. 1. P. 1–266.</mixed-citation><mixed-citation xml:lang="en">NKF: KDOQI Clinical Practice Guidelines for Chronic Kidney Disease: Evaluation, Classification and Stratification // Am J Kidney Dis. 2002. Vol. 39. Suppl. 1. P. 1–266.</mixed-citation></citation-alternatives></ref><ref id="cit50"><label>50</label><citation-alternatives><mixed-citation xml:lang="ru">Onoda N., Kurihara S., Sakurai Y. et al. Evaluation of blood supply to the parathyroid glands in secondary hyperparathyroidism compared with histopathology // Nephrol Dial Transplant. 2003. Vol. 18. Suppl. 3. P. 34–37.</mixed-citation><mixed-citation xml:lang="en">Onoda N., Kurihara S., Sakurai Y. et al. Evaluation of blood supply to the parathyroid glands in secondary hyperparathyroidism compared with histopathology // Nephrol Dial Transplant. 2003. Vol. 18. Suppl. 3. P. 34–37.</mixed-citation></citation-alternatives></ref><ref id="cit51"><label>51</label><citation-alternatives><mixed-citation xml:lang="ru">Pisoni R.L., Wikstrom B., Elder S.J. et al. Pruritus in haemodialysis patients: international results from the Dialysis Outcomes and Practice Patterns Study (DOPPS) // Nephrol Dial Transplant. 2006. Vol. 21. № 12. P. 3495–3505.</mixed-citation><mixed-citation xml:lang="en">Pisoni R.L., Wikstrom B., Elder S.J. et al. Pruritus in haemodialysis patients: international results from the Dialysis Outcomes and Practice Patterns Study (DOPPS) // Nephrol Dial Transplant. 2006. Vol. 21. № 12. P. 3495–3505.</mixed-citation></citation-alternatives></ref><ref id="cit52"><label>52</label><citation-alternatives><mixed-citation xml:lang="ru">Qunibi W., Moustafa M., Muenz L.R. et al. A 1-year randomized trial of calcium acetate versus sevelamer on progression of coronary artery calcification in hemodialysis patients with comparable lipid control: the Calcium Acetate Renagel Evaluation-2 (CARE-2) study // Am J Kidney Dis. 2008. Vol. 51. № 6. P. 952–965.</mixed-citation><mixed-citation xml:lang="en">Qunibi W., Moustafa M., Muenz L.R. et al. A 1-year randomized trial of calcium acetate versus sevelamer on progression of coronary artery calcification in hemodialysis patients with comparable lipid control: the Calcium Acetate Renagel Evaluation-2 (CARE-2) study // Am J Kidney Dis. 2008. Vol. 51. № 6. P. 952–965.</mixed-citation></citation-alternatives></ref><ref id="cit53"><label>53</label><citation-alternatives><mixed-citation xml:lang="ru">Raggi P., Chertov G., Block G. et al. A randomized control trail to evaluate effect of cinacalcet plus low dose vitamin D on vascular calcification in hemodialysis patients // Poster at Clinical Meeting of the National Kidney Foundation, Orlando, FL, April 13–17, 2010.</mixed-citation><mixed-citation xml:lang="en">Raggi P., Chertov G., Block G. et al. A randomized control trail to evaluate effect of cinacalcet plus low dose vitamin D on vascular calcification in hemodialysis patients // Poster at Clinical Meeting of the National Kidney Foundation, Orlando, FL, April 13–17, 2010.</mixed-citation></citation-alternatives></ref><ref id="cit54"><label>54</label><citation-alternatives><mixed-citation xml:lang="ru">Recommendations for management of renal osteodystrophy and Clinical Algorithms on renal osteodystrophy // Nephrol Dial Transplant. 2000. Vol. 15. Suppl. 5. P. 2–57.</mixed-citation><mixed-citation xml:lang="en">Recommendations for management of renal osteodystrophy and Clinical Algorithms on renal osteodystrophy // Nephrol Dial Transplant. 2000. Vol. 15. Suppl. 5. P. 2–57.</mixed-citation></citation-alternatives></ref><ref id="cit55"><label>55</label><citation-alternatives><mixed-citation xml:lang="ru">Schumock G.T., Walton S.M., Lee T. Comparative Effectiveness of Paricalcitol versus Cinacalcet for Secondary Hyperparathyroidism in Patients Receiving Hemodialysis // Nephron Clin Pract. 2010. Vol. 117. № 2. P. 151–159.</mixed-citation><mixed-citation xml:lang="en">Schumock G.T., Walton S.M., Lee T. Comparative Effectiveness of Paricalcitol versus Cinacalcet for Secondary Hyperparathyroidism in Patients Receiving Hemodialysis // Nephron Clin Pract. 2010. Vol. 117. № 2. P. 151–159.</mixed-citation></citation-alternatives></ref><ref id="cit56"><label>56</label><citation-alternatives><mixed-citation xml:lang="ru">Shantouf R.S., Budoff M.J., Ahmadi N. et al. Total and Individual Coronary Artery Calcium Scores as Independent Predictors of Mortality in Hemodialysis Patients // Am J Nephrol. 2010. Vol. 31. № 5. P. 419–425.</mixed-citation><mixed-citation xml:lang="en">Shantouf R.S., Budoff M.J., Ahmadi N. et al. Total and Individual Coronary Artery Calcium Scores as Independent Predictors of Mortality in Hemodialysis Patients // Am J Nephrol. 2010. Vol. 31. № 5. P. 419–425.</mixed-citation></citation-alternatives></ref><ref id="cit57"><label>57</label><citation-alternatives><mixed-citation xml:lang="ru">Tentori F., Albert J.M., Young E.W. et al. The survival advantage for haemodialysis patients taking vitamin D is questioned: findings from the Dialysis Outcomes and Practice Patterns Study // Nephrol Dial Transplant. 2009. Vol. 24. P. 963–972.</mixed-citation><mixed-citation xml:lang="en">Tentori F., Albert J.M., Young E.W. et al. The survival advantage for haemodialysis patients taking vitamin D is questioned: findings from the Dialysis Outcomes and Practice Patterns Study // Nephrol Dial Transplant. 2009. Vol. 24. P. 963–972.</mixed-citation></citation-alternatives></ref><ref id="cit58"><label>58</label><citation-alternatives><mixed-citation xml:lang="ru">Tentori F., Blayney M.J., Albert J.M. et al. Mortality risk for dialysis patients with different levels of serum calcium, phosphorus, and PTH: The Dialysis Outcomes and Practice Patterns Study (DOPPS) // Am J Kidney Dis. 2008. Vol. 52. № 3. P. 519–530.</mixed-citation><mixed-citation xml:lang="en">Tentori F., Blayney M.J., Albert J.M. et al. Mortality risk for dialysis patients with different levels of serum calcium, phosphorus, and PTH: The Dialysis Outcomes and Practice Patterns Study (DOPPS) // Am J Kidney Dis. 2008. Vol. 52. № 3. P. 519–530.</mixed-citation></citation-alternatives></ref><ref id="cit59"><label>59</label><citation-alternatives><mixed-citation xml:lang="ru">Tominaga Y., Matsuoka S., Sato T. et al. Clinical features and hyperplastic pattern of parathyroid gland in hemodialysis patients with advanced secondary hyperparathyroidism refractory to maxacalcitol treatment and required parathyroidectomy // Ther Apher Dial. 2007. Vol. 11. P. 266–273.</mixed-citation><mixed-citation xml:lang="en">Tominaga Y., Matsuoka S., Sato T. et al. Clinical features and hyperplastic pattern of parathyroid gland in hemodialysis patients with advanced secondary hyperparathyroidism refractory to maxacalcitol treatment and required parathyroidectomy // Ther Apher Dial. 2007. Vol. 11. P. 266–273.</mixed-citation></citation-alternatives></ref><ref id="cit60"><label>60</label><citation-alternatives><mixed-citation xml:lang="ru">Tominaga Y., Katayama A., Sato T. et al. Re-operation is frequently required when parathyroid glands remain after initial parathyroidectomy for advanced secondary hyperparathyroidism in uraemic patients // Nephrol Dial Transplant. 2003. Vol. 18. Suppl. 3. P. 65–70.</mixed-citation><mixed-citation xml:lang="en">Tominaga Y., Katayama A., Sato T. et al. Re-operation is frequently required when parathyroid glands remain after initial parathyroidectomy for advanced secondary hyperparathyroidism in uraemic patients // Nephrol Dial Transplant. 2003. Vol. 18. Suppl. 3. P. 65–70.</mixed-citation></citation-alternatives></ref><ref id="cit61"><label>61</label><citation-alternatives><mixed-citation xml:lang="ru">Uhlig K., Berns J.S., Kestenbaum B. et al. KDOQI US Commentary on the 2009 KDIGO Clinical Practice Guideline for the Diagnosis, Evaluation, and Treatment of CKD–Mineral and Bone Disorder (CKD-MBD) // Am J Kidney Dis. 2010. Vol. 55. № 5. P. 773–799.</mixed-citation><mixed-citation xml:lang="en">Uhlig K., Berns J.S., Kestenbaum B. et al. KDOQI US Commentary on the 2009 KDIGO Clinical Practice Guideline for the Diagnosis, Evaluation, and Treatment of CKD–Mineral and Bone Disorder (CKD-MBD) // Am J Kidney Dis. 2010. Vol. 55. № 5. P. 773–799.</mixed-citation></citation-alternatives></ref><ref id="cit62"><label>62</label><citation-alternatives><mixed-citation xml:lang="ru">Ureña P., Jacobson S.H., Zitt E. et al. Cinacalcet and achievement of the NKF/K-DOQI recommended target values for bone and mineral metabolism in real-world clinical practice--the ECHO observational study // Nephrol Dial Transplant. 2009. Vol. 24. № 9. P. 2852–2859.</mixed-citation><mixed-citation xml:lang="en">Ureña P., Jacobson S.H., Zitt E. et al. Cinacalcet and achievement of the NKF/K-DOQI recommended target values for bone and mineral metabolism in real-world clinical practice--the ECHO observational study // Nephrol Dial Transplant. 2009. Vol. 24. № 9. P. 2852–2859.</mixed-citation></citation-alternatives></ref><ref id="cit63"><label>63</label><citation-alternatives><mixed-citation xml:lang="ru">Wetmore J.B., Liu S., Krebill R. et al. Effects of Cinacalcet and Concurrent Low-Dose Vitamin D on FGF23 Levels in ESRD // Clin J Am Soc Nephrol. 2010. Vol. 5. № 1. P. 110–116.</mixed-citation><mixed-citation xml:lang="en">Wetmore J.B., Liu S., Krebill R. et al. Effects of Cinacalcet and Concurrent Low-Dose Vitamin D on FGF23 Levels in ESRD // Clin J Am Soc Nephrol. 2010. Vol. 5. № 1. P. 110–116.</mixed-citation></citation-alternatives></ref><ref id="cit64"><label>64</label><citation-alternatives><mixed-citation xml:lang="ru">Winearls C.G., Glassock R.J. Dissecting and refining the staging of chronic kidney disease // Kidney Int. 2009. Vol. 75. № 10. P. 1009–1014.</mixed-citation><mixed-citation xml:lang="en">Winearls C.G., Glassock R.J. Dissecting and refining the staging of chronic kidney disease // Kidney Int. 2009. Vol. 75. № 10. P. 1009–1014.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
