nidНефрология и диализNephrology and Dialysis1680-44222618-9801Российское диализное обществоnid-987Research ArticleОБЗОРЫ И ЛЕКЦИИREVIEWS AND LECTURESПанцитопения и гемофагоцитарный синдром после трансплантации почки (Обзор литературы с клиническим наблюдением)Pancytopenia and hemophagocytic syndrome after kidney transplantation (Review of the literature with case report)ПрокопенкоЕ. И.ProkopenkoE. I.renalnephron@gmail.comЩербаковаЕ. О.ScherbakovaE. O.noemail@neicon.ruВатазинА. В.VatazinA. V.noemail@neicon.ruГулимоваС. Ю.GulimovaS. U.noemail@neicon.ruМартынюкА. П.MartynyukA. P.noemail@neicon.ruБанинаВ. Б.BaninaV. B.noemail@neicon.ruГагановЛ. Е.GaganovL. E.noemail@neicon.ruМосковский областной научно-исследовательский клинический институт им. М.Ф. ВладимирскогоRussian Federation2010170620251228289Copyright © Прокопенко Е.И., Щербакова Е.О., Ватазин А.В., Гулимова С.Ю., Мартынюк А.П., Банина В.Б., Гаганов Л.Е., 20252025Прокопенко Е.И., Щербакова Е.О., Ватазин А.В., Гулимова С.Ю., Мартынюк А.П., Банина В.Б., Гаганов Л.Е.Prokopenko E.I., Scherbakova E.O., Vatazin A.V., Gulimova S.U., Martynyuk A.P., Banina V.B., Gaganov L.E.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://journal.nephro.ru/jour/article/view/987

Гемофагоцитарный синдром (ГФС) представляет собой редкий, угрожающий жизни синдром, характеризующийся лихорадкой, спленомегалией, панцитопенией и обнаружением в костном мозге и других тканях феномена гемофагоцитоза. В статье обобщены современные данные о патогенезе, клинической картине и подходах к лечению ГФС. Представлено также клиническое наблюдение фатального ГФС, ассоциированного с инфекциями, у больной с почечным трансплантатом.

Hemophagocytic syndrome (HFS) is a rare life-threatening syndrome that is characterized by fever, splenomegaly, pancytopenia and the presence of hemophagocytosis in bone marrow and other tissues. The review summarizes recent data on pathogenesis, clinical presentation and treatment of HFS. We also present a case of fatal infection-associated HFS in a renal transplant recipient.

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The authors declare that there are no conflicts of interest present.