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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">nid</journal-id><journal-title-group><journal-title xml:lang="ru">Нефрология и диализ</journal-title><trans-title-group xml:lang="en"><trans-title>Nephrology and Dialysis</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1680-4422</issn><issn pub-type="epub">2618-9801</issn><publisher><publisher-name>Российское диализное общество</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">nid-990</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group></article-categories><title-group><article-title>Показатель относительного объема крови у пациентов на программном гемодиализе</article-title><trans-title-group xml:lang="en"><trans-title>Relative Blood Volume in Patients on Program Hemodialysis</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Строков</surname><given-names>А. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Strokov</surname><given-names>A. G.</given-names></name></name-alternatives><email xlink:type="simple">medick@bk.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Терехов</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Terehov</surname><given-names>V. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>ФНЦ трансплантологии и искусственных органов имени академика В.И. Шумакова Минздравсоцразвития РФ</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2010</year></pub-date><pub-date pub-type="epub"><day>17</day><month>06</month><year>2025</year></pub-date><volume>12</volume><issue>2</issue><fpage>101</fpage><lpage>105</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Строков А.Г., Терехов В.А., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Строков А.Г., Терехов В.А.</copyright-holder><copyright-holder xml:lang="en">Strokov A.G., Terehov V.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.nephro.ru/jour/article/view/990">https://journal.nephro.ru/jour/article/view/990</self-uri><abstract><p>Поддержание постоянства внутрисосудистого объема на фоне ультрафильтрации – одна из наиболее действенных мер профилактики артериальной гипотензии в ходе гемодиализа. В настоящее время имеются устройства, позволяющие оценить относительные изменения объема крови за счет ультразвукового или оптического анализа крови на входе в диализатор. Целью настоящего исследования явилось определение достоверности показаний двух подобных приборов и изучение влияния различных режимов гемодиализа на показатель относительного объема крови (ООК). В ходе 30 сеансов гемодиализа у 15 пациентов было отмечено четкое совпадение величин гемоглобина и гематокрита, выдаваемых приборами, с лабораторными данными. Изменения ООК по данным мониторов BVM (Fresenius MC, Германия) и Crit-line (In-Line Diagnostics Corporation, США) были практически идентичными. У пациентов с гипергидратацией были отмечены характерные признаки кривой ООК во время гемодиализа: монотонность ее снижения и незначительное максимальное падение ООК (DООК). Отношение DООК к объему ультрафильтрации (DООК/УФ) у таких пациентов не превышало 2,5% на 1 литр. Профилирование скорости УФ и концентрации иона натрия в диализате у 32 пациентов, которым последовательно проводилось по 6 процедур с различными профилями, не позволило существенно повлиять на величину падения ООК. Артериальная гипотензия чаще развивалась при быстром падении ООК на первом часе гемодиализа (6,72 ± 0,86% против 3,86 ± 1,02%; р &lt; 0,05) и при высоком (более 6%/литр) отношении DООК/УФ.</p></abstract><trans-abstract xml:lang="en"><p>Preservation of the intravascular volume is the first choice measure for the prevention of intradialysis hypotension. At present there are devices that allow a continuous monitoring of relative blood volume (RBV) during haemodialysis (HD). The aims of this research were to check data validity of two devices: BVM (Fresenius MC, Germany) and Crit-Line (In-Line Diagnostics Corporation, USA) and to investigate the influence of different dialysis modes on RBV. The coincidence of reading of two monitors and laboratory values of Hb and Ht were assessed during 30 HD sessions in 15 patients. In patients with hyperhydratation RBV curves were monotone and maximum drops of RBV (DRBV) were minor. In all cases relation DRBV/ultrafiltration volume (UF) did not exceed 2,5%/l. In 32 stable HD patients consecutive uses of 5 different UF and Na+ profiles did not decrease DRBV. Intradialysis hypotension was observed in cases of rapid RBV fall during first hour of HD (6,72 ± 0,86% for HD with hypotension vs 3,86 ± 1,02% in general, р &lt; 0,05) and when DRBV/UF was high (&gt;6%/L).</p></trans-abstract><kwd-group xml:lang="ru"><kwd>относительный объем крови</kwd><kwd>артериальная гипотензия</kwd><kwd>профилирование</kwd><kwd>гемодиализ</kwd><kwd>relative blood volume</kwd><kwd>hypotension</kwd><kwd>profiling</kwd><kwd>haemodialysis</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Schroeder K.L., Sallustio J.E., Ross E.A. Continuous haematocrit monitoring during intradialytic hypotension: precipitous decline in plasma refill rates // Nephrol Dial Transplant. 2004. Vol. 19. P. 652–656.</mixed-citation><mixed-citation xml:lang="en">Schroeder K.L., Sallustio J.E., Ross E.A. 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