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Применение заместительной почечной терапии в комплексном лечении тяжелого острого панкреатита

Abstract

The aim of the study to analyze retrospectively the efficiency of renal replacement therapy in treatment of severe acute pancreatitis complicated with systemic inflammation and multiorgan dysfunction. The results of treatment of 55 patients (14 F, 41 M) 22 to 72 years old (average 43,5 ± 16,4) treated in intensive care department of Moscow City Hospital No. 52 from 01.01.2000 to 31.12.2006 were analyzed. All patients had multiorgan dysfunction, with 2 to 5 organs (median 4 (3; 4)) involved and receiving renal replacement therapy. Renal replacement therapy can be successfully used in complex treatment of severe acute pancreatitis provided the dialysis dose of at least 35 ml/kg/h. Independent risk factors of lethality in these patients are - severity estimated according to APACHE II SAPS II scales, and dialysis dose of at least 35 ml/kg/h.

About the Authors

O. L. Podkorytova
Московский городской нефрологический центр, Городская клиническая больница № 52. Кафедра нефрологии ФПДО МГМСУ; г. Москва
Russian Federation


N. A. Tomilina
Московский городской нефрологический центр, Городская клиническая больница № 52. Кафедра нефрологии ФПДО МГМСУ; г. Москва
Russian Federation


B. T. Bikbov
Московский городской нефрологический центр, Городская клиническая больница № 52. Кафедра нефрологии ФПДО МГМСУ; г. Москва
Russian Federation


V. I. Vtorenko
Московский городской нефрологический центр, Городская клиническая больница № 52. Кафедра нефрологии ФПДО МГМСУ; г. Москва
Russian Federation


V. G. Shirinsky
Московский городской нефрологический центр, Городская клиническая больница № 52. Кафедра нефрологии ФПДО МГМСУ; г. Москва
Russian Federation


V. V. Loktev
Московский городской нефрологический центр, Городская клиническая больница № 52. Кафедра нефрологии ФПДО МГМСУ; г. Москва
Russian Federation


N. D. Fedorova
Московский городской нефрологический центр, Городская клиническая больница № 52. Кафедра нефрологии ФПДО МГМСУ; г. Москва
Russian Federation


I. S. Chura
Московский городской нефрологический центр, Городская клиническая больница № 52. Кафедра нефрологии ФПДО МГМСУ; г. Москва
Russian Federation


S. E. Rodnikov
Московский городской нефрологический центр, Городская клиническая больница № 52. Кафедра нефрологии ФПДО МГМСУ; г. Москва
Russian Federation


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Review

For citations:


Podkorytova O.L., Tomilina N.A., Bikbov B.T., Vtorenko V.I., Shirinsky V.G., Loktev V.V., Fedorova N.D., Chura I.S., Rodnikov S.E. . Nephrology and Dialysis. 2008;10(3-4):226-233. (In Russ.)

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