Partial or complete cyclosporine withdrawal convoyed with MMF (Cellcept) administration in kidney allograft recipients
Abstract
In 20 kidney allograft recipients, cyclosporine dosage was gradually reduced below «therapeutic window» convoyed MMF administration. Before starting cyclosporine withdrawal, graft biopsy was performed and revealed normal picture in 6 patients and different pathological findings in the rests. Follow up duration after more then two fold decrease in cyclosporine dosage was 14,6 ± 3,4 months. A statistically significant increase in glomerular filtration rate (p < 0,05) and a decrease in the blood pressure (p < 0,01) were found.
About the Authors
M. M. Kaabak
Российский научный центр хирургии Российской академии медицинских наук
Russian Federation
Russian Federation
J. I. Kurakina
Российский научный центр хирургии Российской академии медицинских наук
Russian Federation
Russian Federation
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Review
For citations:
Kaabak M.M., Kurakina J.I. Partial or complete cyclosporine withdrawal convoyed with MMF (Cellcept) administration in kidney allograft recipients. Nephrology and Dialysis. 2002;4(3):191-195. (In Russ.)
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