Variability of heart rate and arterial pressure in patients with chronic glomerulonephritis and arterial hypertension

Abstract

Nephrogeneous arterial hypertension is both a nephroangiosclerosis progress factor. It favors the development of various cardiovascular complications (infarction, insult). Short but very sharp increases and drops of arterial blood pressure (AP) are particularly adverse. Pathogenesis of such AP leaps is not yet completely understood. An assessment of vegetative nervous system (VNS) activity before and in the moment of AP short increases has been carried out in this research by the way of spectral analysis of the heart rate variability. 20 patients having a hypertonic variant of chronic glomerulonephritis have been examined. It is revealed that at chronic glomerulonephritis the arterial hypertension is not always stable. In most cases a sharp increase of the VNS sympathetic part’s activity occurs just before AP sharp fluctuations.