Case report: fungal infection in a renal transplant recipient as the cause of obstruction and defect of ureter of donor kidney
Abstract
Fungous infections in post-transplant period cause serious problems worldwide. Combined fungal infection invasive candidosis and invasive aspergillosis of the transplant, often lead to the loss of the renal transplant. The early diagnostics and start of treatment are extremely important and vitally necessary. We report a case of successful treatment of fungous infection that caused urological complication in a renal transplant recipient.
About the Authors
A. G. Yankovoy
Vladimirsky Moscow Region Research Clinical Institut, Moscow
Russian Federation
Russian Federation
A. V. Vatasin
Vladimirsky Moscow Region Research Clinical Institut, Moscow
Russian Federation
Russian Federation
E. I. Prokopenko
Vladimirsky Moscow Region Research Clinical Institut, Moscow
Russian Federation
Russian Federation
A. A. Smoliakov
Vladimirsky Moscow Region Research Clinical Institut, Moscow
Russian Federation
Russian Federation
A. A. Sinutin
Vladimirsky Moscow Region Research Clinical Institut, Moscow
Russian Federation
Russian Federation
A. P. Martinuk
Vladimirsky Moscow Region Research Clinical Institut, Moscow
Russian Federation
Russian Federation
References
1. Клясова Г.А., Паровичникова Е.Н., Галстян Е.А. и др. Алгоритмы лечения и профилактики кандидоза и аспергиллеза у взрослых больных лейкозами, лимфомами и депрессиями кроветворения // Гематология и трансфузиология. 2007. № 4. С. 1–5.
2. Масчан А.А., Клясова Г.А., Веселов А.В. Обзор рекомендаций американского общества по инфекционным болезням по лечению аспергиллеза // Клиническая микробиология и антимикробная химиотерапия. 2008. Т. 10. № 2. С. 1–38.
3. Abbott K.C., Hypolite I.O., Poropatich R.K. et al. Hospitalization for fungal infections after renal transplantation in the United States // Transplant. Infect. Dis. 2001. Vol. 3. P. 203–211.
4. Aliff T.B., Maslak P.G., Jurcic J.G. et al. Aspergillus pneumonia in patient with acute leukemia: successful therapy with combination caspofungin and liposomal amphotericin // 43rd annual meeting of American Society of Hematology (Orlando, Florida). 2001. Abstract 1381.
5. Al Soub H., El Deeb Y., Almaslaman I.M., Al Khuwaiter J.Y. Zygomycosis in Qatar: a retrospective review of six cases // Allerg. Immunol. (Paris). 2004. Vol. 36 (10). P. 387–391.
6. Arikan S., Lozano-Chiu M., Paetznick V., Rex J.H. In vitro synergy of caspofungin and amphotericin B against Aspergillusand Fusariumspp // Antimicrob. Agents Chemother. 2002. Vol. 46. P. 245–247.
7. Battaglia M., Ditonno P., Selvaggio O. et al. Kidney transplants from infected donors: our experience // Transplant Proc. 2004. Vol. 36 (3). P. 491–492.
8. Carlos A.Q. Santos and Daniel C. Brennan. Infections in Kidney Transplant Recipient // Kidney Transplantation / Eds. Dianne B. McKay, Steven M. Steinberg. London, 2010. P. 277–309.
9. Colomba C., Antinori S. Fungal infections in transplantation patients// Recenti. Prog. Med. 2003. Vol. 94 (11). P. 516–528.
10. Denning D.W., Evans E.G., Kibbler C.C. Guidelines for the investigation of invasive fungal infections in haematological malignancy and solid organ transplantation. British Society for Medical Mycology // Eur. J. Clin. Microbiol. Infect. Dis. 1997. Vol. 16 (6).P. 424–436.
11. Echo A., Hovsepian R.V., Shen G.K. Localized cecalzygomycosisfollowing renal transplantation // Transpl. Infect. Dis. 2005. Vol. 7 (2).P. 68–70.
12. Elzi L., Laifer G., Bremeric G., Vosbeck J., Mair M. Invasive aspergillosis with myocardial involvement after kidney transplantation // N.D.T. 2005. Vol. 20. P. 631–634.
13. Ergin F., Arslan H., Azap A. et al. Invasive aspergillosis in solid-organ transplantation: report of eight cases and review of the literature // Transpl. Int. 2006. Vol. 16. P. 280–286.
14. Fisher J.F., Woeltje K., Espinel-Ingroff A., Stanfield J., Dipiro J.T. Efficacy of a singl intravenous dose of amphoteric B for Candida urinary tract infection: further favorabl experience // Clin. Microbiol. Infect. 2003. Vol. 9. P. 1024–1027.
15. Gari-Toussaint M., Ngoc L.H., Gigante M. et al. Kidney transplant and Candida albicans arteritis. The importance of analysing the transplant conservation liquid // Presse Med. 2004. Vol. 33 (13). P. 866–868.
16. Gudlaugsson O., Gillespie S., Lee K. et al. Attributable martality of nosocominalcandemia, revisited // Clin. Infect. Dis. 2003. Vol. 37. P. 1127–1137.
17. Hibberd P.L., Rubin R.H. Clinical aspects of fungal infection in organ transplant recipients // Clin. Infect. Dis. 1994. Vol. 19. Suppl 1. P. 33–40.
18. Herbrecht R., Denning D.W., Patterson T.F. et al. Voriconazole versus amphotericin B for primary therapy of invasive aspergillosis // N. Engl. J. Med. 2002. Vol. 347. P. 408.
19. John G.H., Shankar V., Talaulicar G. et al. Epidemiology of systemic mycoses among renal-transplant recipients in India // Transplantation. 2003. Vol. 75. P. 1544–1551.
20. Kontoyiannis D.P., Hachen R., Lewis R.E. Efficacy and toxicity of caspofungin in combination with liposomal amphotericin B as primary or salvage treatment of invasive aspergillosis in patients hematologic malignancies // Cancer. 2003. Vol. 98. P. 292–299.
21. Leleu G., Aegerter P., Guidet B. Systemic candidiasis in intensive care unit: a multicenter, matched-cohort study // J. Crit. Care. 2002. Vol. 17. P. 168–175.
22. Lin S.J., Schranz J., Teutsch S.M. Aspergillosis case-fatality rate: systematic review of the literature // Clin Infect Dis. 2001. Vol. 32. P. 358–366.
23. Mora-Duarte J., Betts R., Rotstein C. et al. Comparison of Caspofungin and amphotericin B for invasive candidiasis // N. Engl. J. Med. 2002. Vol. 347. P. 2020–2029.
24. Odds F.C. Treatment of invasive fungal disease: will combination antifungal therapy reduce mortality? // 13th European Cpngress of Clinical Microbiology and Infectious Diseases. 2003. May 10–13. Glasgow. UK.
25. Ostrosky-Zeichner L., Marr K.A., Rex J.H., Cohen S.H. Amphotericin B: Time for a New “Gold Standart” // Clin Infect Dis. 2003. Vol. 37. P. 415–425.
26. Pappas P.G., Kauffman C.A., Andres D. et al. Clinical Practice Guidelines for the Management of Candidiasis: 2009 Update by the Infectious Diseases Society of America // Clinical Infectious Diseases. 2009. Vol. 48. P. 503–535.
27. Rarrido J., Lerma JL., Haras M. et al. Pseudoaneurysm of the iliac artery secondary to Aspergillus infection in two recipients of kidney transplants from the same donor // Am. J. Kidney Dis. 2003. Vol. 41 (2). P. 488–492.
28. Singh N., Gayowski T., Wagener M.M. et al. Invasive fungal infections in renal transplant recipients receiving tacrolimus as the primary immunosuppressive agent // Clin. Infect. Dis. 1997. Vol. 24. P. 179–185.
29. Soubani A.O., Chandrasekar P.H. The clinical spectrum of pulmonary aspergillosis// Chest. 2002. Vol. 121. P. 1988–1999.
30. Takahashi K. Mycosis in kidney transplant patients // Nippon IshinkinGakkaiZasshi 2001. Vol. 42 (4). P. 201–204.
31. Walsh T., Teppler H., Donowitz G.R. et al. Caspofungin versus lipisomal amphotericin B for empirical antifungal therapy in patients with persistent fever and neutropenia // N. Engl. J. Med. 2004. Vol. 351. P. 1391–1402.
32. WegnerB., BaerP., GauerS. et al. Caspofungin is less nephtrotoxic than amphotericin B in vitro and predominantly damages distal renal tubular cells // Nephrol. Dial. Transplant. 2005. Vol. 20. P. 2971–2079.
33. Wu G., Vilchez R.A., Eidelman B., Fung J., Kormos R., Kusne S. Cryptococcal meningitis: an analysis among 5,521 consecutive organ transplant recipients // Transpl. Infect. Dis. 2002. Vol. 4 (4). P. 183–188.
Review
For citations:
Yankovoy A.G., Vatasin A.V., Prokopenko E.I., Smoliakov A.A., Sinutin A.A., Martinuk A.P. Case report: fungal infection in a renal transplant recipient as the cause of obstruction and defect of ureter of donor kidney. Nephrology and Dialysis. 2012;14(2):128-132. (In Russ.)
Views:
2
Email this article 