Secondary hyperparathyroidism and cardiac valve calcification in patients with predialysis CKD stages and on the renal replacement therapy
Abstract
The prevalence and structure of the valvular calcification and its relationship to arterial hypertension, calcium-phosphate disorders, anemia, malnutrition–inflammation syndrome, achieving of volume balance were studied in 96 patients on predialysis care, hemodialysis and peritoneal dialysis with echocardiography. A high prevalence of the combined mitral-aortic calcification was revealed. The age and duration of predialysis arterial hypertension were the predictive factors for cardiac valve calcification in CAPD patients, but not for predialysis patients. Heart calcification was not linked with hyperparathyroidism, hyperphosphatemia and hypercalciemia for this group. We found association of left ventricular hypertrophy with the intensity of valve calcinosis in predialysis patients. Both concentric and eccentric types of myocardial remodeling were observed.
About the Authors
D. V. Korotkiy
St.-Petersburg medical academy for posgraduate education; Mariinsky City hospital, St.-Petersburg
Russian Federation
Russian Federation
R. P. Gerasimchuk
Mariinsky City hospital, St.-Petersburg
Russian Federation
Russian Federation
T. I. Makeeva
St.-Petersburg medical academy for posgraduate education
Russian Federation
Russian Federation
O. P. Zavaritskaya
Pokrov city hospital, St.-Petersburg
Russian Federation
Russian Federation
A. Yu. Zemchenkov
St.-Petersburg I.I. Mechnikov state medical academy; Mariinsky City hospital, St.-Petersburg
Russian Federation
Russian Federation
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For citations:
Korotkiy D.V., Gerasimchuk R.P., Makeeva T.I., Zavaritskaya O.P., Zemchenkov A.Yu. Secondary hyperparathyroidism and cardiac valve calcification in patients with predialysis CKD stages and on the renal replacement therapy. Nephrology and Dialysis. 2011;13(2):089-095. (In Russ.)
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