Pauci-immune crescentic glomerulonephritis complicating Sjögren’s syndrome
Abstract
Primary Sjogren’s syndrome (PSS) is an autoimmune disease characterized by lymphocytic infiltration of the salivary and lacrimal glands. PSS is common in adults, especially in middle aged women, but rare in children. The most common form of renal involvement in PSS is a tubulointerstitial nephritis. Renal dysfunction is usually mild or subclinical. Glomerulonephritis (GN) is rare in patients with PSS and most patients have membranous or membranoproliferative GN. We report a 12-year-old girl with PSS who developed a pauci immune crescentic GN. To our knowledge, this association has not been previously described in children.
About the Authors
M. Iu. Kagan
ГУЗ «Областная детская клиническая больница», г. Оренбург
Russian Federation
Russian Federation
O. A. Vorobyeva
ГУЗ «Ленинградское областное патологоанатомическое бюро» г. Санкт-Петербург
Russian Federation
Russian Federation
References
1. Bartunkova J., Sediva A., Vencovsky J., Tesar V. Primary Sjogren’s syndrome in children and adolescents: proposal for diagnostic criteria. Clin Exp Rheumatol, 1999. Vol. 17. P. 381-386.
2. Bossini N., Savoldi S., Franceschini F., Mombelloni S., Baronio M., Cavazzana I., Viola B.F., Valzorio B., Mazzucchelli C., Cattaneo R., Scolari F., Maiorca R. Clinical and morphological features of kidney involvement in primary Sjogren’s syndrome. Nephrol Dial Transplant, 2001. Vol. 16. P. 2328-2336.
3. Cimaz R., Casadei A., Rose C. et al. Primary Sjogren syndrome in the pediatric age: a multicentre survey. Eur J Pediatr, 2003. Vol. 162. P. 661-665.
4. Goules A., Masouridi S., Tzioufas A., Ioannidis J., Skopouli F., Moutsopoulos H. Clinically significant and biopsy-documented renal involvement in primary Sjogren syndrome. Medicine, 2000. Vol. 79. P. 241-249.
5. Hernandez J., Rodrigo E., De Francisco A., Val F., Gonzalez-Macias J., Riancho J. ANCA-associated pauci-immune crescentic glomerulonephritis complicating Sjogren’s syndrome. Nephrol Dial Transplant, 1996. Vol. 11. P. 2313-2315.
6. Houghton K., Malleson P., Cabral D., Petty R., Tucker L. Primary Sjogren’s syndrome in children and adolescents: are proposed diagnostic criteria applicable? J Rheumatol, 2005. Vol. 32. P. 2225-2232.
7. Jonsson R., Bowman S., Gordon T. Sjogren’s syndrome. In: Koopman W.J. (ed) Arthritis and allied conditions. 15 th edition. Baltimore: Lippincott Williams & Wilkins, 2005. P. 1682-1705.
8. Kamachi M., Migita K., Tominaga M., Ichinose Y., Nakamura H., Origuchi T., Urayama S., Hida A., Kawakami A., Kawabe Y., Taguchi T., Eguchi K. Sjogren’s syndrome complicated by MPO_ANCA positive crescentic glomerulonephritis. Nephrol Dial Transplant, 1999. Vol. 14. P. 1033-1034.
9. Kobayashi I., Furuta H., Tame A. et al. Complications of childhood Sjogren syndrome. Eur J Pediatr, 1996. Vol. 155. P. 890-894.
10. Ostuni P.A., Ianniello A., Sfriso P., Mazzola G., Andretta M., Gambari P.F. Juvenile onset of primary Sjogren’s syndrome: report of 10 cases. Clin Exp Rheumatol, 1996. Vol. 14. P. 689-693.
11. Pertovaara M., Korpela M., Kouri T., Pasternack A. The occurrence of renal involvement in primary Sjogren’s syndrome: a study of 78 patients. Rheumatology, 1999. Vol. 38. P. 1113-1120.
12. Palcoux J.B., Janin-Mercier A., Campagne D., Fonck Y., Betail G. Sjogren syndrome and lupus erythematosus nephritis. Arch Dis Child, 1984. Vol. 59. P. 175-177.
13. Tatsumi H., Tateno S., Hiki Y., Shigematsu H., Kobayashi Y. Crescentic glomerulonephritis associated with membranous nephropathy in a case with primary Sjogren’s syndrome. Nephrol Dial Transplant, 1998. Vol. 13. P. 2624-2627.
14. Skopouli F.N. Kidney injury in Sjogren’s syndrome. Nephrol Dial Transplant, 2001. Vol. 16 (Suppl. 6). P. 63-64.
Review
For citations:
Kagan M.I., Vorobyeva O.A. Pauci-immune crescentic glomerulonephritis complicating Sjögren’s syndrome. Nephrology and Dialysis. 2009;11(1):53-56. (In Russ.)
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