Infections after kidney transplantation Review
Abstract
Infectious complications after kidney transplantation occur in 36% of patients in the first year after transplantation and in in 52% of them in the first 6 months We review modern data concerning the infection appearance in the first month after kidney transplantation (mainly urinary tract infections) and those which are revealed later (viral and opportunistic infections). The predictors of the development of infections after kidney transplantation: hypoalbuminemia, low concentration of IgG1, decrease in the CD4 level, leucopenia, chronic infections, diabetes mellitus, the absence of antibodies to herpes-zoster-virus, CMV-positive status, HBV- and/or HCV are considered. The importance of the level of procalcitonin for differentiation of infectious complications and allograft rejection is emphasized. Standard measures for preventing infections after kidney transplantation: kotrimoksazol-forte for 6–12 months for all patients, valganciclovir for 3 first months for the CMV-positive donors independently on the CMV-status of the recipients and necessity of evaluation of the status of vaccination are discussed and evaluated.
About the Author
K. A. Kabulbayev
A.N. Syzganov National Scientific Surgical Centre, Almaty, Kazakhstan
Russian Federation
Russian Federation
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Review
For citations:
Kabulbayev K.A. Infections after kidney transplantation Review. Nephrology and Dialysis. 2009;11(4):293-298. (In Russ.)
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