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Nomenclature for kidney function and disease: report of a Kidney Disease: Improving Global Outcomes (KDIGO) Consensus Conference

https://doi.org/10.28996/2618-9801-2020-3-271-292

Abstract

The worldwide burden of kidney disease is rising, but public awareness remains limited, underscoring the need for more effective communication by stakeholders in the kidney health community. Despite this need for clarity, the nomenclature for describing kidney function and disease lacks uniformity. In June 2019, Kidney Disease: Improving Global Outcomes (KDIGO) convened a Consensus Conference with the goal of standardizing and refining the nomenclature used in the English language to describe kidney function and disease, and of developing a glossary that could be used in scientific publications. Guiding principles of the conference were that the revised nomenclature should be patient-centered, precise, and consistent with nomenclature used in the KDIGO guidelines. Conference attendees reached general consensus on the following recommendations: (i) to use “kidney” rather than “renal” or “nephro-” when referring to kidney disease and kidney function; (ii) to use “kidney failure” with appropriate descriptions of presence or absence of symptoms, signs, and treatment, rather than “end-stage kidney disease”; (iii) to use the KDIGO definition and classification of acute kidney diseases and disorders (AKD) and acute kidney injury (AKI), rather than alternative descriptions, to define and classify severity of AKD and AKI; (iv) to use the KDIGO definition and classification of chronic kidney disease (CKD) rather than alternative descriptions to define and classify severity of CKD; and (v) to use specific kidney measures, such as albuminuria or decreased glomerular filtration rate (GFR), rather than “abnormal” or “reduced” kidney function to describe alterations in kidney structure and function. A proposed 5-part glossary contains specific items for which there was general agreement. Conference attendees acknowledged limitations of the recommendations and glossary, but they considered standardization of scientific nomenclature to be essential for improving communication.

About the Authors

S. Levey Andrew
Tufts Medical Center
Russian Federation


Eckardt Kai-Uwe
Charité - Universitätsmedizin Berlin
Russian Federation


M. Dorman Nijsje
American Journal of Kidney Diseases
Russian Federation


L. Christiansen Stacy
Journal of the American Medical Association
Russian Federation


J. Hoorn Ewout
University Medical Center Rotterdam
Russian Federation


R. Ingelfinger Julie
Harvard Medical School; Massachusetts General Hospital
Russian Federation


A. Inker Lesley
Tufts Medical Center
Russian Federation


Levin Adeera
University of British Columbia
Russian Federation


MehrotraO Rajnish
University of Washington School of Medicine
Russian Federation


M. Palevsky Paul
University of Pittsburgh School of Medicine
Russian Federation


A. Perazella Mark
Yale University School of Medicine; Veterans Affairs Medical Center
Russian Federation


Tong Allison
University of Sydney; The Children’s Hospital at Westmead
Russian Federation


J. Allison Susan
Nature Reviews Nephrology
Russian Federation


Bockenhauer Detlef
Great Ormond Street Hospital for Children NHS Foundation Trust; University College London
Russian Federation


P. Briggs Josephine
Journal of the American Society of Nephrology
Russian Federation


S. Bromberg2O Jonathan
University of Maryland School of Medicine, Baltimore
Russian Federation


Davenport Andrew
Royal Free London NHS Foundation Trust
Russian Federation


I. Feldman Harold
Perelman School of Medicine at the University of Pennsylvania
Russian Federation


Fouque Denis
Centre Hospitalier Lyon Sud
Russian Federation


T. Gansevoort Ron
University of Groningen
Russian Federation


S. Gill John
University of British Columbia
Russian Federation


L. Greene Eddie
Mayo Clinic
Russian Federation


R. Hemmelgarn3O Brenda
University of Calgary
Russian Federation


Kretzler Matthias
University of Michigan
Russian Federation


Lambie Mark
Keele University
Russian Federation


H. Lane Pascale
University of Oklahoma Health Sciences Center
Russian Federation


Laycock Joseph
Pediatric Nephrology
Russian Federation


E. Leventhal Shari
American Society of Nephrology
Russian Federation


Mittelman Michael
American Living Organ Donor Fund
Russian Federation


Morrissey Patricia
Kidney International
Russian Federation


Ostermann4O Marlies
Guy’s & St Thomas’ Hospital
Russian Federation


Rees Lesley
Great Ormond Street Hospital for Children NHS Foundation Trust
Russian Federation


Ronco Pierre
Sorbonne Université; Institut National de la Santé et de la Recherche Médicale; Assistance Publique-Hôpitaux de Paris, Hôpital Tenon
Russian Federation


Schaefer Franz
Heidelberg University
Russian Federation


St. Clair Jennifer
National Kidney Foundation
Russian Federation


Vinck Caroline
Nephrology Dialysis Transplantation
Russian Federation


B. Walsh Stephen
University College London
Russian Federation


E. Weiner Daniel
Tufts Medical Center
Russian Federation


Cheung Michael
Kidney Disease: Improving Global Outcomes (KDIGO)
Russian Federation


Jadoul5O Michel
Université Catholique de Louvain
Russian Federation


C. Winkelmayer Wolfgang
Baylor College of Medicine
Russian Federation


References

1. Plantinga LC, Boulware LE, Coresh J, et al. Patient awareness of chronic kidney disease: trends and predictors. Arch Intern Med 2008; 168:2268-2275.

2. Saran R, Robinson B, Abbott KC, et al. US Renal Data System 2018 Annual Data Report: Epidemiology of Kidney Disease in the United States. Am J Kidney Dis 2019; 73:A7-A8.

3. James SL. Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet 2018; 392:1789-1858.

4. Global Burden of Disease 2017 Causes of Death Collaborators. Global, regional, and national age-sex-specific mortality for 282 causes of death in 195 countries and territories, 1980-2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet 2018; 392:1736-1788.

5. Hsu CY, Chertow GM. Chronic renal confusion: insufficiency, failure, dysfunction, or disease. Am J Kidney Dis 2000; 36:415-418.

6. Kidney Disease: Improving Global Outcomes (KDIGO) Acute Kidney Injury Work Group. KDIGO clinical practice guideline for acute kidney injury. Kidney Int Suppl 2012; 2:1-138.

7. Kidney Disease: Improving Global Outcomes (KDIGO) CKD Work Group. KDIGO 2012 clinical practice guideline for the evaluation and management of chronic kidney disease. Kidney Int Suppl 2013; 3:1-150.

8. Kidney Disease: International Global Outcomes. Consensus Conference on Nomenclature for Kidney Function & Disease. Available at: https://kdigo.org/conferences/nomenclature/. Accessed April 15, 2020.

9. Tong A, Levey AS, Eckardt KU, et al. Patient and caregiver perspectives on terms used to describe kidney health [e-pub ahead of print]. Clin J Am Soc Nephrol. https://doi.org/10.2215/CJN.00900120. Accessed April 16, 2020.

10. Iverson C. Nomenclature. In: Christiansen S, Iverson C, Flanagin A, et al. American Medical Association (AMA) Manual of Style: A Guide for Authors and Editors. 11th ed. Oxford, UK: Oxford University Press; 2020:642-644.

11. Eckardt KU, Coresh J, Devuyst O, et al. Evolving importance of kidney disease: from subspecialty to global health burden. Lancet 2013; 382:158-169.

12. Levey AS, Levin A, Kellum JA. Definition and classification of kidney diseases. Am J Kidney Dis 2013; 61:686-688.

13. Fouque D, Kalantar-Zadeh K, Kopple J, et al. A proposed nomenclature and diagnostic criteria for protein-energy wasting in acute and chronic kidney disease. Kidney Int 2008; 73:391-398.

14. Neri M, Villa G, Garzotto F, et al. Nomenclature for renal replacement therapy in acute kidney injury: basic principles. Crit Care 2016; 20:318.

15. Glassberg KI, Stephens FD, Lebowitz RL, et al. Renal dysgenesis and cystic disease of the kidney: a report of the Committee on Terminology, Nomenclature and Classification, Section on Urology, American Academy of Pediatrics. J Urol 1987; 138:1085-1092.

16. Eckardt KU, Alper SL, Antignac C, et al. Autosomal dominant tubulointerstitial kidney disease: diagnosis, classification, and management - a KDIGO consensus report. Kidney Int 2015; 88:676-683.

17. Kriz W, Bankir L. A standard nomenclature for structures of the kidney. The Renal Commission of the International Union of Physiological Sciences (IUPS). Kidney Int 1988; 33:1-7.

18. Kidney Tissue Atlas Ontology. Available at: https://bioportal.bioontology.org/ontologies/KTAO. Accessed April 15, 2020.

19. American Medical Association. American Medical Association (AMA) Manual of Style. 10th ed. Oxford, UK: Oxford University Press; 2007.

20. Committee on the Quality of Healthcare in the United States. Institute of Medicine. Crossing the Quality Chasm: A New Health System for the 21st Century. Washington, DC: National Academy Press; 2001.

21. Chen GM, Pather SR, DeLisser HM. Trends in the use of common words and patient-centric language in the titles of medical journals, 1976-2015.JAMA Netw Open. 2019; 2:e191083.

22. Oxford Dictionary of English. 3rd ed. Oxford, UK: Oxford University Press; 2010.

23. Kidney Precision Medicine Project. Available at: https://kpmp.org/. Accessed April 15, 2020.

24. Centers for Medicare and Medicaid Services. End-stage renal disease (ESRD). Available at: https://www.cms.gov/Medicare/Coordination-of-Benefits-and-Recovery/Coordination-of-Benefits-and-Recovery-Overview/End-Stage-Renal-Disease-ESRD/ESRD.html. Accessed April 15, 2020.

25. Kidney Disease: International Global Outcomes. KDIGO Controversies Conference on Acute Kidney Injury. April, 2019; Rome, Italy. Available at: https://kdigo.org/conferences/aki-conference/.Accessed April 15, 2020.

26. Davison SN, Levin A, Moss AH, et al. Executive summary of the KDIGO Controversies Conference on Supportive Care in Chronic Kidney Disease: developing a roadmap to improving quality care. Kidney Int 2015; 88:447-459.

27. James MT, Levey AS, Tonelli M, et al. Incidence and prognosis of acute kidney diseases and disorders using an integrated approach to laboratory measurements in a universal health care system. JAMA Netw Open 2019; 2:e191795.

28. Chawla LS, Bellomo R, Bihorac A, et al. Acute kidney disease and renal recovery: consensus report of the Acute Disease Quality Initiative (ADQI) 16 Workgroup. Nat Rev Nephrol2017; 13:241-257.

29. National Kidney Foundation. K/DOQI clinical practice guidelines for chronic kidney disease: evaluation, classification, and stratification. Am J Kidney Dis 2002; 39(Suppl 1):S1-266.

30. Floege J, Barbour SJ, Cattran DC, et al. Management and treatment of glomerular diseases (part 1): conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference. Kidney Int 2019;95:268-280.

31. Christiansen S, Iverson C, Flanagin A, et al. American Medical Association (AMA) Manual of Style: A Guide for Authors and Editors. 11th ed. Oxford, UK: Oxford University Press; 2020.


Review

For citations:


Andrew S.L., Kai-Uwe E., Nijsje M.D., Stacy L.Ch., Ewout J.H., Julie R.I., Lesley A.I., Adeera L., Rajnish M., Paul M.P., Mark A.P., Allison T., Susan J.A., Detlef B., Josephine P.B., Jonathan S.B., Andrew D., Harold I.F., Denis F., Ron T.G., John S.G., Eddie L.G., Brenda R.H., Matthias K., Mark L., Pascale H.L., Joseph L., Shari E.L., Michael M., Patricia M., Marlies O., Lesley R., Pierre R., Franz S., Jennifer S.C., Caroline V., Stephen B.W., Daniel E.W., Michael Ch., Michel J., Wolfgang C.W. Nomenclature for kidney function and disease: report of a Kidney Disease: Improving Global Outcomes (KDIGO) Consensus Conference. Nephrology and Dialysis. 2020;22(3):271-292. (In Russ.) https://doi.org/10.28996/2618-9801-2020-3-271-292

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ISSN 1680-4422 (Print)
ISSN 2618-9801 (Online)