Long-term clinical results of endovascular correction of renal artery stenosis

Relevance: renal artery stenosis is a serious pathology leading to the loss of renal function and progression of hypertension. Objective: to evaluate the long-term clinical results of endovascular correction of renal artery stenosis (ECRAS). Materials and methods: we analyzed the long-term results of endovascular correction of renal artery stenosis (ECRAS) in 167 patients who received 205 interventions. All patients had hypertension established in accordance with WHO recommendations (1999), and chronic kidney disease (CKD) determined by glomerular filtration rate (GFR) using CKD-EPI formula. We evaluated EСRAS results at 1 and 3 years after the intervention. We have analyzed patient survival, renal artery survival (estimated by the renal artery patency before occlusion or before the development of hemodynamically significant restenosis), the functional state of kidneys (according to CKD-stage, serum creatinine level and GFR), as well as the average blood pressure (BP) and the degree of BP control before and after EСRAS. Results: survival rate of patients after ECRAS was: 1 year 99% patients, 3 years and 5 years 93% patients, and survival of renal artery: 92%, 90% and 84% respectively. Creatinine level at 1 and 3 years after EСRAS significantly decreased (p<0,001, Student's test), as did the CKD-stage at 1 and 3 years after EСRAS (p=0,001, Wilcoxon test). GFR at 1 and 3 years after EСRAS significantly increased (p<0,001, p<0,01, Student's test). The average BP and the degree of BP control at 1 and 3 years after EСSRAS also significantly decreased (p<0,001, Wilcoxon test). Conclusions: EСRAS is highly effective in restoring renal artery patency. It allows one to preserve and improve renal function, as well as more effectively control hypertension.

почечная артерия, стеноз, атеросклероз, стентирование, ангиопластика, эндоваскулярная коррекция, renal artery, stenosis, atherosclerosis, stenting, angioplasty, endovascular correction

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