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Renal tubular acidosis

Abstract

Ренальный тубулярный ацидоз (РТА) - группа канальцевых заболеваний почек, которые характеризуются нарушением реабсорбции бикарбоната, секреции водородных ионов или сочетанием обоих дефектов и приводят к метаболическому ацидозу при сохранной клубочковой фильтрации.

About the Authors

T. V. Vashourina
НИИ педиатрии ГУ НЦЗД РАМН, г. Москва
Russian Federation


T. V. Sergeeva
НИИ педиатрии ГУ НЦЗД РАМН, г. Москва
Russian Federation


References

1. Alper S.L. Genetic diseases of acid-base transporters. Annu Rev Physiol 2002; 64: 899-923.

2. Alper S.L., Stuart-Tilley A.K., Biemesderfer E.D. et al. Immunolocalization of AE2 anion exchanger in rat kidney. Am J Physiol 1997; 273: F.601-F.614.

3. Arai K., Zachman K., Chrousos G.P. Polymorphisms of amiloride sensitive sodium channel subunits in five sporadic cases of pseudohypoaldosteronism: do they have pathological potential? J Clin Endocrinol Metab 1999; 84: 2434-2437.

4. Baird R.N., Orlowski J., Szabo E.Z. et al. Molecular cloning, genomic organization, and functional expression of Na+/H+ exchanger isoform 5 (NHE 5) from human brain. J Biol Chem 1999; 274: 4377-4382.

5. Battle D., Flores G. Underlying defects in distal renal tubular acidosis. New understandings. Am J Kidney Dis 1996; 27: 896-915.

6. Batlle D.C., Ghanekar H., Jain S. et al. Hereditary distal renal tubular acidosis: New understandings. Annu Rev Med 2001; 52: 471-484.

7. Brenes L.G., Brenes J.M., Hernandez M.M. Familial proximal renal tubular acidosis. A distinct disease entity. Am J Med 1977; 63: 244-252.

8. Cunningham J., Fraher L.J., Clemens T.L. et al. Chronic acidosis with metabolic bone disease. Am J Med 1982; 73: 199-204.

9. DuBose T.D. Hyperkalemic hyperchloremic metabolic acidosis: pathophysiologic insights. Kidney Int 1997; 51: 591-602.

10. Hanukoglu A. Type I pseudohypoaldosteronism includes two clinically and genetically distinct entities with either renal or multiple target organ defects. J Clin Endocrinol Metab 1991; 73: 936-944.

11. Iragashi T., Inatomi J., Sekine T. et al. Mutations in SLC4A4 cause permanent isolated proximal renal tubular acidosis with ocular abnormalities. Nature Genet 1999; 23: 264-266.

12. Iragashi T., Ishii T., Watanabe K. et al. Persistent isolated proximal renal tubular acidosis - a sistemic disease with a distinct clinical entity. Pediatr Nephrol 1994; 8: 70-71.

13. Gordon R.D., Geddes R.A., Pawsey G.K. et al. Hypertension and severe hyperkalemia associated with suppression of renin and aldosterone and completely reversed by dietary sodium restriction. Aust Ann Med 1970; 4: 287-294.

14. Kamel K.S., Briceno L.F., Sanchez M.D. et al. A new classification for renal defects in net acid excretion. Am J Kidney Dis 1997; 29: 136-146.

15. Karet F.E. Inherited renal tubular acidosis. Adv Nephrol 2000; 30: 147-161.

16. Karet F.E., Finberg K.E., Nelson R.D. et al. Mutations in the gene encoding B1 subunit of H+-ATPase cause renal tubular acidosis with sensoneural deafness. Nature Genet 1999; 21: 84-90.

17. Nagai R., Kooh S.W., Balfe J.W. et al. Renal tubular acidosis and osteopetrosis with carbonic anhydrase II deficiency: pathogenesis of impaired acidification. Pediatr Nephrol 1997; 11: 633-636.

18. Nash M.A., Torrado A.D., Greifer I. et al. Renal tubular acidosis in infants and children. J Pediatr 1972; 80: 738-748.

19. Norman M.E., Feldman N.I., Cohn R.M. et al. Urinary citrate excretion in the diagnosis of distal renal tubular acidosis. J Pediatr 1978; 92: 394-400.

20. Rodrigues-Soriano J. New insights into the pathogenesis of renal tubular acidosis - from functional to molecular studies. Pediatr Nephrol 2000; 14: 1121-1136.

21. Rodrigues-Soriano J. Renal Tubular Acidosis: The Clinical Entity. J Am Soc Nephrol 2002; 13: 2160-2170.

22. Rodrigues-Soriano J., Vallo A. Renal tubular acidosis. Pediatr Nephrol 1990; 4: 268-275.

23. Rodriguez-Soriano J., Vallo A., Castillo G. et al. Natural history of primary distal renal tubular acidosis treated since infancy. J Pediatr 1982; 101: 669-676.

24. Romero M.F., Boron W.F. Electrogenic Na+/HCO3- cotransporters: cloning and phisiology. Annu Rev Physiol 1999; 61: 699-723.

25. Rutherford P.A. Expression of Na+/H+ exchanger isoforms in the kidney - implications for renal function and disease. Nephrol Dial Transplant 1996; 11: 1711-1713.

26. Simpson D.P. Citrate excretion: a window on renal metabolism. Am J Physiol 1983; 244: F223-F234.

27. Soleimani M., Burnham C.E. Physiology and molecular aspects of the Na+/HCO3- cotransporters in health and disease processes. Kidney Int 2000; 57: 371-384.

28. Spitzer A., Edelmann C.M., Goldberg L. et al. Short stature, hyperkalemia, and acidosis: a defect in renal transport of potassium. Kidney Int 1973; 3: 251-257.

29. Tanner M.J. Band 3 anion exchanger and its involvement in erythrocyte and kidney disorders. Curr Opin Hematol 2002; 9: 133-139.

30. Tanner M.J. The structure and function of band 3 (AE1): recent developments. Mol Membr Biol 1997; 14: 155-165.

31. Yu H., Freedman B.I., Rich S.S. et al. Human Na+/H+ exchanger genes: identification of polimorphisms by radiation hybrid mapping and analysis of linkage in end stage renal disease. Hypertension 2000; 35: 135-143.


Review

For citations:


Vashourina T.V., Sergeeva T.V. Renal tubular acidosis. Nephrology and Dialysis. 2003;5(2):122-127. (In Russ.)

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