Preview

Nephrology and Dialysis

Advanced search

Complex therapy of chronic renal failure in patients with multiple myeloma

Abstract

14-years expirience of treatment of patients with multiple myeloma (MM) complicated by renal failure is presented. Mean age of 40 patients was 57,6 ± 7,7. The predominant renal disease was myeloma nephropathy. Before diagnosing, MM 9 patients had chronic diffuse kidney lesion. Patients with double pathology (MM and uremia) were treated by both nephrologists and hematologists. The average life expectancy was 24,1 ± 12,1 months. Observed data showed the possibility of prolongation of patient’s survival when hemodialysis is applied. Some patients were given multiple polychemotherapy courses. Clinico-hematological remission was achieved and patients were socialy adapted.

About the Authors

L. S. Birukova
Гематологический научный центр РАМН, г. Москва
Russian Federation


L. M. Tangieva
Гематологический научный центр РАМН, г. Москва
Russian Federation


V. S. Timohov
Гематологический научный центр РАМН, г. Москва
Russian Federation


E. V. Fetisova
Гематологический научный центр РАМН, г. Москва
Russian Federation


A. V. Pivnik
Гематологический научный центр РАМН, г. Москва
Russian Federation


S. A. Marina
Гематологический научный центр РАМН, г. Москва
Russian Federation


References

1. Андреева Н.Е. Диагностика и лечение миеломной болезни. М., 1998: 3-26.

2. Алексеев Г.А., Андреева Н.Е. Миеломная болезнь. М., 1996: 133-161, 161-169.

3. Бирюкова Л.С. Острая почечная недостаточность в гематологической клинике: Дисс. … д-ра мед. наук. М., 2002.

4. Бирюкова Л.С., Володяева Е.Б., Фетисова Е.В. и др. Острая и хроническая почечная недостаточность у больных с миеломной болезнью. Тер. арх. 1999; 71; 7: 58-63.

5. Воробьев А.И. Руководство по гематологии. - М., 1979; 1: 244-267.

6. Дамбахер М.А. Остеопороз и активные метаболиты витамина D3. М., 1996: 3-26.

7. Камаева О.И. Миеломная болезнь и почки. Тер. арх. 1997; 69; 6: 73-75.

8. Цыкалова В.А., Шотемор Ш.Ш., Рощина Л.С., Зарубина Н.А., Боброва Л.Т., Мокеева Р.А. Дифференциальная диагностика множественной миеломы и первичного гиперпаратиреоза. Гематология и трансфузиология 1988; 1: 48-51.

9. Шулутко Е.М., Буланова Е.Л., Городецкий В.М., Галстян Г.М., Будянский В.М. Проблема сосудистого доступа в гематологической клинике. Проблемы гематологии и переливания крови 1995; 2: 26.

10. Шулутко Е.М., Галстян Г.М., Готман Л.Н., Васильев С.А. Катетер-ассоциированные тромбозы (КАТ) центральных вен. Проблемы гематологии и переливания крови 2000; 4: 62.

11. Casio F.G., Pense T.V., Shapiro F.L. Kjellstrand C.M. Severe renal failure in multiple myeloma. Clin. Nephrol. 1981 Apr; 15 (4): 206-10. Related Articles, Books, Link Out.

12. Сlark A.D., Shetty A., Soutar R. Renal failure and multiple myeloma: Patogenesis and treatment of renal failure and management of underlying myeloma. Blood rev. 1999. Jun; 13 (2): 79-90.

13. Сooper G.L. Hopkins C.C. Rapid diagnosis of intravascular cateter associated infection by direct gram staining of cateter segments. N. Engl. J Med. 1985; 312: 1142-1147.

14. Jhоnson W.J., Kyle R.A., Dahlberg P.J. Dialysis in the treatment of multiple myeloma. Mayo Clin. Proc. 1980. Feb; 55 (2): 65-72.

15. Irish A.B., Winearls C.G., Littlewood T. Presentation and survival of patients with sever renal failure and myeloma. QJM. 1997. Dec; 90 (12): 773-80.

16. Kappers-Klunne M.C., Degener J.E., Stijnen T., Abels J. Complications from long-term indvelling central venous catheters in haematology patients with special reference to infection. Cancer. 1989; 64: 1747-1752.

17. Knudsen L.M., Hansen M.T., Lokkegaard H. Renal insufficiency in myelomatosis. Causes and treatment. Ugeskr Laeger 1993. Nov. 22; 154 (47): 3823-7.

18. Lazarus H.M., Adelstein D.J., Herzig Rh., Smith M.C. Long-term survival of patients with multiple myeloma and acute renal failure at presentation. Am. J. Kidney Dis. 1983. Mar; 2 (5): 521-5.

19. Marino P.L. Catheter sepsis. In: Paul L Marino (eds). The ICU book, Philadelphia, Lea @ Febiger 1991: 603-614.

20. Menichetti F., Del-Favero A., Bukaneve G. et al. Teicoplanin in empirical combined antibiotic therapy of bacteraemias in bone marrow transplantant patients. J. Antimicrob. Chemoter. 1988, 21 Suppl. A: 105-111.

21. Molby L., Hansen H.H., Jensen E.L. Development and treatment of renal insufficiency in multiple myeloma. Ugesker Laeger 1994 Jul. 25; 156 (30): 4343-7.

22. Randall R.E., Williams W.C. Jr., Mullinax F., Tung M.Y., Still W.J. Manifestations of systemic light chain deposition. Am. J. Med. 1976. Feb; 60 (2): 293-9.

23. Sharland A., Snowdon L., Joshua D.E., Gibson J., Tiller D.J. Hemodialysis: an appropriate in myeloma-induced renal failure. Am. J. Kidney Dis. 1997. Dec.; 30 (6): 786-92.

24. Vulikc D., Radlovik O., Stanojcic A., Rajic M. Treatment of renal insufficiency in patients with multiple myeloma. Srp. Arh Celok Lek 1996; 124 Suppl. 1: 53-5.


Review

For citations:


Birukova L.S., Tangieva L.M., Timohov V.S., Fetisova E.V., Pivnik A.V., Marina S.A. Complex therapy of chronic renal failure in patients with multiple myeloma. Nephrology and Dialysis. 2002;4(2):98-105. (In Russ.)

Views: 16


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 1680-4422 (Print)
ISSN 2618-9801 (Online)