Blood pressure variability and left ventricular hypertrophy in hemodialysis patients
https://doi.org/10.28996/1680-4422-2018-1-56-63
Abstract
Aim: arterial hypertension is one of the main causes of the left ventricular hypertrophy (LVH) in hemodialysis (HD) patients. The aim of this study was to investigate the correlation between LVH and blood pressure variability in hemodialysis patients. Patients and methods: 62 patients (M/F: 32/30, 55±13 years) after 1 year hemodialysis treatment were studied. Echocardiographic evaluation was performed after dialysis and left ventricular mass index (LVMI) was calculated. All patients underwent 24-hour ambulatory BP monitoring (ABPM), predialysis and postdialysis systolic and diastolic BP was determined and Home Blood Pressure Measurements (HBPM) was performed. Average values for 24-hour BP, daytime BP, and nighttime BP were calculated, average values of HBPM during 30 days including hemodialysis session days and pre- and postdialysis office BP were analysis and variability of BP parameters was calculated. Results: left ventricular hypertrophy was detected in 32 (51.6%) patients. Mean LVMI was 123.41±39.26 g/m2. Pulse blood pressure was higher in patients with LVH with all methods BP measuring. Predialysis systolic BP variability was determined as the independent factor is associated with LVMI in multivariate regression analysis (R2=0.31; β=0.34; t=2.69; P=0.009). Conclusions: our study showed that patients on the long term (more 1 year) hemodialysis treatment have higher pulse BP with all methods of measurement. The predialysis systolic BP variability was associated with the left ventricular hypertrophy independently of the blood pressure level.
About the Authors
E. O. Borodulina
Department of Nephrology and Hemodialysis, Medical Private Institution of additional professional education "Nefrosovet"
Russian Federation
Russian Federation
A. M. Shutov
Medical Faculty, Ulyanovsk State University, Russia, Ulyanovsk
Russian Federation
Russian Federation
V. A. Serov
Medical Faculty, Ulyanovsk State University, Russia, Ulyanovsk
Russian Federation
Russian Federation
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Review
For citations:
Borodulina E.O., Shutov A.M., Serov V.A. Blood pressure variability and left ventricular hypertrophy in hemodialysis patients. Nephrology and Dialysis. 2018;20(1):56-63. (In Russ.) https://doi.org/10.28996/1680-4422-2018-1-56-63
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