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The Haemostasis Abnormality in Patients with Uraemic Pericarditis

Abstract

Pericarditis is one of severe complications in patients with advanced uraemia. The aim of this study was to investigate the haemostasis abnormality related with uraemic pericarditis. We observed 117 patients with endstage renal disease. In 67 of them uraemia was complicated with pericarditis. The increase in disseminated intravascular coagulation was found to be accomponied with pericarditis. In these cases the decrease of hypocoagulation, the severe fibrinolysis depression, the raise of trombin level and the decrease of plasma anticoagulation ability were observed. The investigation of effusion showed the low fibrinogen level in combination with low anticoagulation and fibrinolytic activity. We suppose that the haemostasis disorders may be one of the mechanisms responsible for the uraemic pericarditis.

About the Authors

I. L. Melchina
Центр трансплантации почки и гемодиализа, Барнаул
Russian Federation


I. N. Schoyhet
Центр трансплантации почки и гемодиализа, Барнаул
Russian Federation


M. Yu. Feoctistova
Центр трансплантации почки и гемодиализа, Барнаул
Russian Federation


References

1. Баркаган З.С. Основы диагностики нарушений гемостаза. М.: «Ньюдиамед-АО», 1999, 224 с.

2. Гогин Е.Е. Болезни перикарда. М., 1979; 192 с.

3. Лопаткин Н.А., Румянцев В.Б., Букаев Ю.Н. и др. Синдром диссеминированного внутрисосудистого свертывания крови при урологических заболеваниях. Урол. и нефрол. 1997; 3: 3-8.

4. Неймарк М.И. Нарушение гемокоагуляции и фибринолиза у больных ХПН в процессе лечения гемодиализом и пути их коррекции. Тер. Архив. 1984; 7: 48-53.

5. Неймарк М.И. Диагностика и терапия нарушений гемостаза, микротромбоэмболизации сосудов легких при программном гемодиализе. Автореф.дисс. д-р. мед.наук. М., 1989; 34.

6. Cochran M., Lawton S., Rowlands L.M. Fibrinous pericarditis and fibrinolysis in chronic dialysis patients. Clin. Nephrol. 1979; 11: 23-25.

7. Handbook of dialysis. Eds. J.T.Daugirdas, T.S.Ing. - Second ed. - Little, Brown and Co., 1994; 744.

8. Massry S.G., Glassock R.J. Textbook of nephrology. - Third ed. - Williams & Wilkins. 1995; 2025.

9. Opatrny K. Jr. Haemostasis disorders in chronic renal failure. Kidney Int. Suppl. 1997; 62: 87-89.


Review

For citations:


Melchina I.L., Schoyhet I.N., Feoctistova M.Yu. The Haemostasis Abnormality in Patients with Uraemic Pericarditis. Nephrology and Dialysis. 1999;1(2-3):143-146. (In Russ.)

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ISSN 1680-4422 (Print)
ISSN 2618-9801 (Online)