The case of Waldenstrom’s macroglobulinaemia complicated with membranoproliferative glomerulonephritis
Abstract
We report here the case of Waldenstrom’s Macroglobulinaemia ( MW) complicated with mesangioproliferative glomerulonephritis (MPGN) which appeared in a woman of 76 years old. The main clinical features of the disease were nephrotic syndrom associated with vasculitis. The blood immunochemistry revealed a monoclonal secretion of IgM. The changes typical for MPGN were observed in kidney biopsy. We suppose that MPGN was caused by the deposition on the GBM of immune complexes containing the antibody against monoclonal IgM.
About the Authors
A. M. Rosenfeld
Московский городской нефрологический центр при Городской клинической больнице № 52
Russian Federation
Russian Federation
L. S. Biryukova
Московский городской нефрологический центр при Городской клинической больнице № 52
Russian Federation
Russian Federation
V. A. Doronin
Московский городской нефрологический центр при Городской клинической больнице № 52
Russian Federation
Russian Federation
A. V. Schubina
Московский городской нефрологический центр при Городской клинической больнице № 52
Russian Federation
Russian Federation
V. A. Varschawsky
Московский городской нефрологический центр при Городской клинической больнице № 52
Russian Federation
Russian Federation
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Review
For citations:
Rosenfeld A.M., Biryukova L.S., Doronin V.A., Schubina A.V., Varschawsky V.A. The case of Waldenstrom’s macroglobulinaemia complicated with membranoproliferative glomerulonephritis. Nephrology and Dialysis. 1999;1(2-3):186-190. (In Russ.)
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