Structure of acute kidney injury in patients requiring renal replacement therapy at an cancer hospital

Abstract

Aim: the study was performed to optimize the planning of the methods of renal replacement therapy (RRT) in a cancer hospital. Materials and methods: the medical records of 187 patients treated in Irkutsk Regional Oncology Center and 687 renal replacement therapy procedures due to renal failure were analyzed. Results: in the retrospective analysis, some differences in the structure of acute renal injury were revealed in patients required renal replacement therapy, compared with those in non-oncological patients. It has been determined that the greatest proportion of renal pathology falls on postrenal acute renal injury caused by cases of long-term undiagnosed cancer of pelvic organs which are often in Russia. The decisive indicators for RRT were: the severity of uremic intoxication, decompensated metabolic acidosis, uncorrected hyperkalemia etc. The RRT procedures were both intermittent and continuous character; the intermittent hemodialysis has some advantage. Continuous procedures (CRRT) are used primarily in patients with unstable hemodynamic parameters. In 7 patients, renal replacement therapy was performed due to extrarenal indications. Conclusion: in order to optimize the planning of RRT in the cancer hospital, it is necessary to take into account that intermittent hemodialysis is more often than continuous methods of RRT (65% vs. 33.71%) with only 1.29% for the remaining RRT methods (SCUF and other).