Successful treatment of carcinoma in functioning renal transplant

Kidney transplantation is the optimal treatment for patients with terminal chronic renal failure. However renal transplant recipients have an increased risk of various malignancies due to long immunosuppression, and persistent viral infections. Malignant tumors can develop in native non-functioning kidney, and in the transplanted kidney - functioning or non-functioning. Tumors of the renal transplant (RT) is a rare disease, but the incidence of its development may be underestimated. According to different authors, tumors of RT develop in 0.19-0.78% of patients. Most of these tumors are papillary carcinoma and have a low degree of malignancy. Sources of tumor growth are different: carcinoma may have donor nature and may develop de novo from cells of the recipient. Most of the recipients at the time of detection of the RT tumor have no clinical symptoms, and the neoplasm is detected by chance, during a routine ultrasound examination of the transplanted kidney. Here we describe a case of successful surgical treatment of kidney transplant carcinoma in 22 years after transplantation and correction of immunosuppression after the tumor removal. Incidence, time of arising, clinical and hystological features, treatment options of kidney transplant tumors are discussed. The need for regular cancer screening in RT recipients is justified.

трансплантация почки, иммуносупрессия, онкологические осложнения, рак трансплантата, kidney transplantation, immunosuppression, oncological complications, graft carcinoma

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