Hemodiafiltration: attention on the volume Review
Abstract
In the review the data supporting the efficiency of on-line hemodiafiltration regarding hard outcomes are briefly described as well as detailed data from recently published three big randomized trials (CONTRAST, Turkish on-line HDF and ESHOL). Being different in primary outcomes, all RCT demonstrated in the post hoc analysis that benefits in hard outcomes received patients with convection volumes greater than 20-24 l/session. The obtaining of such volumes requires resolving issues with hemoconcentration along the dialyzer. The role of HDF in RRT will be defined more exactly in evaluation of its efficiency and cost-efficiency in comparison with other methods of dialysis safety, tolerability and efficacy improvement.
About the Authors
A. Yu. Zemchenkov
City Mariinsky hospital - City nephrology center; I.I. Mechnikov North-West State medical university
Russian Federation
Russian Federation
R. P. Gerasimchuk
City Mariinsky hospital - City nephrology center
Russian Federation
Russian Federation
A. B. Sabodash
B. Braun Avitum Russland Clinics - Nevsky nephrology center
Russian Federation
Russian Federation
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Review
For citations:
Zemchenkov A.Yu., Gerasimchuk R.P., Sabodash A.B. Hemodiafiltration: attention on the volume Review. Nephrology and Dialysis. 2014;16(1):128-138. (In Russ.)
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