The role of the kidney in hormonal mechanisms of homeostasis
Abstract
The main function of the kidneys is the maintenance of water-salt homeostasis. Hormonal mechanisms of kidney function allow it to participate in the regulation of many body functions. This is achieved by the consistent work of transport systems of the kidneys, and the hormonal (endocrine, paracrine, autocrine) mechanisms. In a brief overview we show the involvement of the kidneys in some physiological and pathological processes which require precise coordination of hormonal and transport systems of the kidneys and the whole body. The peculiarity of involvement of the kidney through angiotensin II in the development of the fetus during pregnancy is described. Flexibility and plasticity of regulation of water-salt metabolism in various forms of pathology can be attributed to these functions of the kidneys to the category of homeostasis.
About the Authors
Y. Y. Bagrov
I.M. Sechenov Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Science, St. Petersburg
Russian Federation
Russian Federation
N. B. Manusova
I.M. Sechenov Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Science, St. Petersburg
Russian Federation
Russian Federation
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Review
For citations:
Bagrov Y.Y., Manusova N.B. The role of the kidney in hormonal mechanisms of homeostasis. Nephrology and Dialysis. 2014;16(3):322-327. (In Russ.)
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